I-Azacitidine

-Delile

• Ngaphambi kokuthatha i-azacitidine,
• I-Azacitidine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Azacitidine isetshenziselwa ukwelapha i-acute myeloid leukemia (AML; umdlavuza wamangqamuzana amhlophe egazi) kubantu abadala abathuthuka ngemuva kokwelashwa ngamakhemikhali, kepha abangakwazi ukuqedela ukwelashwa okunamandla kokwelapha. I-Azacitidine isekilasini lemithi ebizwa ngama-demethylation agents. Isebenza ngokusiza umnkantsha wethambo ukukhiqiza amangqamuzana egazi ajwayelekile nangokubulala amaseli angajwayelekile.

I-Azacitidine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye nsuku zonke ezinsukwini zokuqala eziyi-14 zomjikelezo wezinsuku ezingama-28. Udokotela wakho uzonquma ukuthi kufanele uwuphindaphinde kangaki lo mjikelezo ngokuya ngempendulo yakho kulo muthi neminye imiphumela emibi ongayithola. Thatha i-azacitidine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-azacitidine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Uma isikhumba sakho sihlangana ne-powder evela ngaphakathi kwamathebulethi, geza indawo evulekile ngokushesha ngensipho namanzi. Uma amehlo noma umlomo wakho uhlangana nempuphu evela ngaphakathi kwamathebulethi, gcwalisa indawo ngokushesha ngamanzi.

Udokotela wakho uzokunika imithi yokuvikela isicanucanu nokuhlanza imizuzu engama-30 ngaphambi kokuthola umthamo ngamunye we-azacitidine kwimijikelezo emibili yokuqala. Udokotela wakho angaqhubeka ukukunikeza lo muthi ngemijikelezo yakamuva, uma kudingeka.

Uma uhlanza ngemuva kokuthatha i-azacitidine, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho anganciphisa umthamo wakho noma ayeke ukwelashwa kwakho okwesikhashana noma unomphela uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-azacitidine.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-azacitidine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-azacitidine, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-azacitidine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthatha i-azacitidine. Uma ungowesifazane, kuzodingeka uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise izilawuli zokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho futhi okungenani izinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Uma ungowesilisa futhi umlingani wakho angakhulelwa, kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nezinyanga ezi-3 ngemuva komthamo wakho wokugcina. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha i-azacitidine, shayela udokotela wakho. I-Azacitidine ingalimaza umbungu.
• ungancelisi ibele ngenkathi uthatha i-azacitidine kanye neviki elingu-1 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesilisa nabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha i-azacitidine.
• kufanele wazi ukuthi i-azacitidine ivame ukudala isifo sohudo, esingaba nzima. Udokotela wakho mhlawumbe uzokutshela ukuthi uthathe umuthi olwa nohudo ukuvikela ukomisa (ukulahleka kwamanzi amaningi emzimbeni wakho) ngesikhathi sokwelashwa kwakho nge-azacitidine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa umthamo noma uma ungaphuzi umthamo wakho ngesikhathi esijwayelekile, wuthathe ngokushesha ngangokunokwenzeka ngalolo suku. Thatha umthamo wakho olandelayo ngesikhathi esijwayelekile ngosuku olulandelayo. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Azacitidine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ukukhathala
• ubuhlungu besisu
• ubuhlungu obuhlangene
• ubuhlungu bemisipha
• isiyezi
• ubuhlungu ezandleni noma emilenzeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• umphimbo obuhlungu, umkhuhlane, amakhaza, ubuhlungu bomzimba, noma ezinye izimpawu zokutheleleka
• ukuphefumula okuncane noma isikhumba esiphaphathekile
• ukulimaza okungajwayelekile noma ukopha, ukugabha okunegazi, ukugabha okubukeka njengezizathu zekhofi, noma okumnyama, okulindile noma okokuchitha igazi

I-Azacitidine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Gcina la ma-canic amabili (i-agent eyomisa) ebhodleleni lemithi ukugcina amaphilisi omile. Ungawadli ama-canic desiccant.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-azacitidine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• U-Onureg^®