I-Casirivimab ne-Imdevimab Injection

-Delile

• Ngaphambi kokuthola i-casirivimab ne-imdevimab,
• ICasirivimab ne-imdevimab kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisesigabeni se-HOW, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo.

Inhlanganisela ye-casirivimab ne-imdevimab okwamanje ifundelwa ukwelashwa kwesifo se-coronavirus 2019 (COVID-19) esibangelwa igciwane le-SARS-CoV-2.

Imininingwane yesivivinyo somtholampilo enomkhawulo kuphela etholakalayo ngalesi sikhathi ukuxhasa ukusetshenziswa kwe-casirivimab ne-imdevimab ekwelapheni i-COVID-19. Imininingwane eminingi iyadingeka ukwazi ukuthi i-casirivimab ne-imdevimab isebenza kanjani ekwelapheni i-COVID-19 kanye nemicimbi engemihle evela kuyo.

Ukuhlanganiswa kwe-casirivimab ne-imdevimab akukaze kutholakale ukubuyekezwa okujwayelekile ukuze kuvunyelwe i-FDA ukuthi isetshenziswe. Kodwa-ke, i-FDA ivume Ukugunyazwa Kokusetshenziswa Okuphuthumayo (i-EUA) ukuvumela abantu abadala nabangekho ezibhedlela abaneminyaka engu-12 ubudala nangaphezulu abanezimpawu ze-COVID-19 eziphakathi nendawo zokuthola umjovo we-casirivimab kanye ne-imdevimab.

Khuluma nodokotela wakho ngezingozi nezinzuzo zokuthola lo muthi.

Inhlanganisela ye-casirivimab ne-imdevimab isetshenziselwa ukwelapha ukutheleleka kwe-COVID-19 kubantu abadala abathile abangalalisiwe esibhedlela nezingane ezineminyaka engu-12 ubudala nangaphezulu ezinesisindo okungenani esingamakhilogremu angama-88 (40 kg) futhi ezinezimpawu ze-COVID-19 eziphakathi nendawo ezilinganayo. Inhlanganisela isetshenziswa kubantu abanezimo ezithile zezempilo ezibenza babe sengozini enkulu yokuthola izimpawu ezinzima ze-COVID-19 noma isidingo sokulaliswa esibhedlela ngokungenwa yi-COVID-19. I-Casirivimab ne-imdevimab basesigabeni semithi ebizwa ngama-antibody monoclonal. Basebenza ngokuvimba ukusebenza kwento ethile yemvelo emzimbeni ukunqanda ukusabalala kwegciwane.

Inhlanganisela ye-casirivimab ne-imdevimab iza njengesisombululo (uketshezi) sokuxutshwa noketshezi bese ujovwa kancane emthanjeni ngaphezu kwemizuzu engama-60 ngudokotela noma unesi. Inikezwa njengomthamo wesikhathi esisodwa ngokushesha okukhulu ngemuva kokuhlolwa okuhle kwe-COVID-19 futhi kungakapheli izinsuku eziyi-10 ngemuva kokuqala kwezimpawu zokutheleleka ze-COVID-19 ezinjengomkhuhlane, ukukhwehlela, noma ukuphefumula okuncane.

Inhlanganisela ye-casirivimab ne-imdevimab ingadala ukusabela okungathi sína ngesikhathi nangemva kokufakwa komuthi. Udokotela noma umhlengikazi uzokuqapha ngokucophelela ngenkathi uthola umuthi nangehora elilodwa ngemuva kokuwuthola. Tshela udokotela wakho noma umhlengikazi ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokumnika: umkhuhlane, ukugodola, isicanucanu, ikhanda, ukuguquka kokushaya kwenhliziyo yakho, ubuhlungu besifuba, ubuthakathaka noma ukukhathala, ukudideka, ukuphefumula kanzima noma ukuphefumula okuncane, ukuphefumula , ukucasuka komphimbo, ukuqubuka, isifuba, ukulunywa, ubuhlungu bemisipha noma ukuqaqamba, ukujuluka, isiyezi ikakhulukazi lapho umile, noma ukuvuvukala kobuso, umphimbo, ulimi, izindebe, noma iso. Udokotela wakho angadinga ukwehlisa ukumnika kwakho noma ayeke ukwelashwa kwakho uma unale miphumela emibi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-casirivimab ne-imdevimab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-casirivimab, imdevimab, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-casirivimab kanye ne-imdevimab. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imishanguzo yokuzivikela njenge-cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, ne-tacrolimus (i-Astagraf, i-Envarsus, i-Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma ngabe uke waba nezimo zezempilo noma wake waba nazo.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola i-casirivimab ne-imdevimab, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

ICasirivimab ne-imdevimab kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• Ubuhlungu, ukopha, ukulinyazwa kwesikhumba, ukuba buhlungu, ukuvuvukala, noma ukutheleleka endaweni yokujova

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisesigabeni se-HOW, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo.

• imfiva
• ukuphefumula kanzima
• izinguquko ekushayeni kwenhliziyo
• ukukhathala noma ubuthakathaka
• ukudideka

ICasirivimab ne-imdevimab kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nomjovo we-casirivimab kanye ne-imdevimab.

Kufanele uqhubeke nokuzihlukanisa njengoba uqondiswe ngudokotela wakho futhi ulandele imikhuba yezempilo yomphakathi njengokugqoka imaski, ukuqhela emphakathini, nokugeza izandla kaningi.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

I-American Society of Health-System Pharmacists, Inc. imele ukuthi lolu lwazi olumayelana ne-casirivimab ne-imdevimab lwenziwa ngezinga elifanele lokunakekelwa, nangokuhambisana nezindinganiso zobungcweti emkhakheni. Abafundi bayaxwayiswa ukuthi inhlanganisela ye-casirivimab ne-imdevimab akuyona indlela yokwelashwa evunyelwe yesifo se-coronavirus 2019 (i-COVID-19) ebangelwe yi-SARS-CoV-2, kodwa kunalokho, iyaphenywa futhi okwamanje iyatholakala ngaphansi, kwemvume yokusebenzisa i-FDA esiphuthumayo ( EUA) ekwelapheni i-COVID-19 emnene kuya kokulingene kwezinye iziguli eziphuma ngaphandle. I-American Society of Health-System Pharmacists, Inc. ayenzi izethulo noma amawaranti, ayivezi noma asikiswanga, kufaka phakathi, kodwa kungagcini, kunoma yisiphi isiqinisekiso esisetshenzisiwe sokuthengiselana kanye / noma ukuqina ngenhloso ethile, maqondana nolwazi, futhi ikakhulukazi izilahla zonke lezi ziqinisekiso. Abafundi bemininingwane mayelana ne-casirivimab ne-imdevimab bayelulekwa ukuthi i-ASHP ayibophezelekile kwimali eqhubekayo yolwazi, nganoma yimaphi amaphutha noma ukushiywa, kanye / noma eminye imiphumela evela ekusetshenzisweni kwalolu lwazi. Abafundi bayelulekwa ukuthi izinqumo maqondana nokwelashwa kwezidakamizwa ziyizinqumo eziyinkimbinkimbi zezokwelapha ezidinga isinqumo esizimele, esinolwazi sompetha ofanele wezokunakekelwa kwezempilo, futhi imininingwane equkethwe yilolu lwazi inikezwa ngenhloso yokwaziswa kuphela. I-American Society of Health-System Pharmacists, Inc. ayikukhuthazi noma ukuncoma ukusetshenziswa kwanoma imuphi umuthi. Lolu lwazi olumayelana ne-casirivimab ne-imdevimab akufanele lubhekwe njengezeluleko zesiguli ngasinye. Ngenxa yokushintsha kwemininingwane yolwazi ngezidakamizwa, uyelulekwa ukuba ubonane nodokotela noma usokhemisi wakho mayelana nokusetshenziswa kwemitholampilo kwanoma imuphi umuthi.

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