ICabotegravir neRilpivirine Injections

-Delile

• Ngaphambi kokuthola imijovo ye-cabotegravir ne-rilpivirine,
• Imijovo yeCabotegravir ne-rilpivirine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisohlwini lwe-INDLELA noma IZIKHATHI ZOKUQapha, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Imijovo yeCabotegravir kanye ne-rilpivirine isetshenziselwa ukuhlangana ekwelapheni ukutheleleka ngegciwane lesandulela ngculaza i-human immunodeficiency type 1 (HIV-1) kubantu abadala abathile. ICabotegravir isekilasini lemithi ebizwa nge-HIV integrase inhibitors. I-Rilpivirine isekilasini lemithi ebizwa nge-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Le mithi isebenza ngokunciphisa inani le-HIV egazini. Yize i-cabotegravir ne-rilpivirine zingayelaphi i-HIV, zinganciphisa amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthola le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

Imijovo yeCabotegravir kanye ne-rilpivirine enwetshiwe (esebenza isikhathi eside) iza njengokulengiswa (uketshezi) ukuze kujovwe emsipheni ngumhlinzeki wezokunakekelwa kwempilo. Uzothola imijovo ye-cabotegravir ne-rilpivirine kanye ngenyanga enikezwa njengomjovo womuthi ngamunye ezinqeni zakho.

Ngaphambi kokuthola imijovo yakho yokuqala ye-cabotegravir ne-rilpivirine, kuzofanele uthathe ithebhulethi ye-cabotegravir (Vocabria) ne-rilpivirine (Edurant) ngomlomo (ngomlomo) kanye ngosuku inyanga eyodwa (okungenani izinsuku ezingama-28) ukubona ukuthi uyakwazi yini ukubekezelela lokhu imithi.

Umjovo wokukhipha i-Rilpivirine owandisiwe ungadala ukusabela okubi kakhulu ngemuva nje kokuthola umjovo. Udokotela noma umhlengikazi uzokuqapha ngalesi sikhathi ukuze aqiniseke ukuthi awunampendulo ebucayi emithini. Tshela udokotela wakho noma umhlengikazi ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokujova kwakho: ukuphefumula kanzima, amajaqamba esiswini, ukujuluka, ukuba ndikindiki komlomo, ukukhathazeka, ukuqhuma, ikhanda elikhanyayo, noma isiyezi.

Imijovo ye-Cabotegravir ne-rilpivirine enwetshiwe isiza ukulawula i-HIV, kepha ayiyelaphi. Gcina onke ama-aphoyintimenti ukuthola imijovo ye-cabotegravir ne-rilpivirine enwetshiwe noma ngabe uzizwa uphilile. Uma uphuthelwa isikhathi sokuqokwa sokuthola imijovo ekhishwa yi-cabotegravir kanye ne-rilpivirine, isimo sakho singaba nzima ukwelashwa.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola imijovo ye-cabotegravir ne-rilpivirine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cabotegravir, rilpivirine, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-cabotegravir kanye ne-rilpivirine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Epitol, Equetro, Tegretol), dexamethasone (Decadron), oxcarbazepine (Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rifadin, Rifater), i-rifapentine (Priftin), noma iSt John's wort. Udokotela wakho mhlawumbe uzokutshela ukuthi ungatholi imijovo ye-cabotegravir ne-rilpivirine uma uphuza eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Nexterone, Pacerone); i-anagrelide (Agrylin); i-azithromycin (iZithromax); i-chloroquine; i-chlorpromazine; i-cilostazol; i-ciprofloxacin (Cipro); i-citalopram (Celexa); i-clarithromycin (i-Biaxin); i-dofetilide (Tikosyn); i-donepezil (i-Aricept); i-erythromycin (i-E-Mycin, i-Eryc, i-Ery-Tab, i-PCE); i-flecainide (iTambocor); i-fluconazole (iDiflucan); i-haloperidol (iHaldol); eminye imithi yokwelapha i-HIV / AIDS; ibutilide (Corvert); levofloxacin; i-methadone (i-Dolophine); moxifloxacin (Velox); i-ondansetron (iZuplenz, iZofran); eminye imishanguzo yamaNNRTI yokwelapha i-HIV / AIDS; ipentamidine (NebuPent, Pentam); ipimozide (i-Orap); procainamide; i-quinidine (ku-Nuedexta); i-sotalol (iBetapace, iSorine, iSotylize); futhi thioridazine. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-cabotegravir ne-rilpivirine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma uke waba nokudangala noma esinye isifo sengqondo, noma isifo sesibindi, kufaka phakathi ukutheleleka kwesifo sohlobo lwe-hepatitis B noma u-C.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola imijovo ye-cabotegravir ne-rilpivirine, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthola imijovo ye-cabotegravir ne-rilpivirine.
• kufanele wazi ukuthi imijovo ye-cabotegravir ne-rilpivirine ingadala ushintsho emicabangweni yakho, ekuziphatheni, noma empilweni yengqondo. Shayela udokotela wakho ngokushesha uma uba nezimpawu ezilandelayo ngenkathi uthola imijovo ye-rilpivirine: ukucindezeleka okusha noma okuya kuba kubi; noma ucabanga ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo. Qiniseka ukuthi umndeni wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukushayela udokotela wakho uma ungakwazi ukufuna ukwelashwa wedwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa ukuqokwa komjovo we-cabotegravir ne-rilpivirine ngezinsuku ezingaphezu kwezingu-7, shayela udokotela wakho ngokushesha ukuze nixoxe ngezinketho zokwelashwa.

Imijovo yeCabotegravir ne-rilpivirine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu, isisa, ukuvuvukala, ububomvu, ukulunywa, ukulinyazwa, noma ukufudumala endaweni yomjovo
• imfiva
• ukukhathala
• ikhanda
• ubuhlungu bemisipha, ithambo, noma iqolo
• isicanucanu
• ubunzima bokulala noma ukulala
• isiyezi
• ukuzuza kwesisindo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezisohlwini lwe-INDLELA noma IZIKHATHI ZOKUQapha, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka noma ngaphandle: umkhuhlane; ukukhathala; ubuhlungu bemisipha noma obuhlangene; ukuvuvukala kobuso, izindebe, umlomo, ulimi, noma umphimbo; amabhamuza esikhumba; ubunzima bokuphefumula noma ukugwinya; izilonda zomlomo; ubomvu noma ukuvuvukala kwamehlo; ubuhlungu ohlangothini lwesokunene sesisu; indle ephaphathekile; isicanucanu; ukuhlanza; noma umchamo onombala omnyama
• amehlo aphuzi noma isikhumba; ubuhlungu besisu sangaphezulu kwesokudla; ukulinyazwa; ukopha; ukulahlekelwa ukudla; ukudideka; umchamo ophuzi noma onsundu; noma indle ephaphathekile

Imijovo yeCabotegravir ne-rilpivirine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola le mithi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho emijoweni ye-cabotegravir kanye ne-rilpivirine.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nemijovo ye-cabotegravir ne-rilpivirine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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