Umbralisib

-Delile

• Ngaphambi kokuthatha umbralisib,
• I-Umbralisib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Umbralisib isetshenziselwa ukwelapha i-marginal zone lymphoma (MZL; umdlavuza okhula kancane oqala ngohlobo lwamaseli amhlophe egazi avame ukulwa nokutheleleka) kubantu abadala umdlavuza wabo obuyile noma ongaphendulanga ohlotsheni oluthile lwemithi. Ibuye isetshenziselwe ukwelapha i-follicular lymphoma (FL; uhlobo lomdlavuza oluqala kumaseli amhlophe egazi) kubantu abadala umdlavuza wabo obuyile noma ongaphendulanga kweminye imithi emithathu. Umbralisib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba ukusebenza kweprotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunqanda ukusabalala kwamangqamuzana omdlavuza.

Umbralisib uza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye nsuku zonke ngokudla. Thatha umbralisib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha umbralisib njengoba uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Uma uhlanza ngemuva kokuphuza umuthi, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha umbralisib,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-umbralisib, i-aspirin, noma imuphi omunye umuthi, i-tartrazine (udayi ophuzi kokunye ukudla okucutshungulwayo nemithi), noma yiziphi izithako ezibhebheni ze-umbralisib. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma unesifo. Futhi, tshela udokotela wakho uma uke waba nezinkinga zesisu noma zamathumbu noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba ngubaba wengane. Uma ungowesifazane, kuzodingeka uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise izilawuli zokubeletha ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho futhi okungenani inyanga eyodwa ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho kufanele nisebenzise ukulawulwa kokuzalwa ngesikhathi sokwelashwa kwakho nge-umbralisib nangenyanga e-1 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha umbralisib, shayela udokotela wakho ngokushesha. I-Umbralisib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha umbralisib kanye nenyanga e-1 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi umbralisib kungadala izinkinga zokuzala emadodeni. Lokhu kungathinta amandla akho okuzala ingane. Khuluma nomhlinzeki wakho wezokunakekelwa kwezempilo uma unezinkinga mayelana nokuzala.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa ngumthamo ngaphansi kwamahora ayi-12, thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Kodwa-ke, uma uphuthelwa umthamo ngaphezu kwamahora we-12, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Umbralisib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuhlanza
• isicanucanu
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• ukukhathala
• ukuvuvukala kobuso, izandla, noma izinyawo
• ubuhlungu bemisipha, iqolo, intamo, noma ithambo
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• umkhuhlane, umphimbo obuhlungu, ukukhwehlela, ukuphefumula kanzima, ukuphefumula, ukubanda, noma ezinye izimpawu zokutheleleka
• isifo sohudo esibi; igazi kwizitulo zakho noma emnyama, izitulo zokulinda; umchamo obomvana noma onsundu; ukuhlanza igazi noma ikhofi emhlabathini; noma ukukhwehlela igazi
• amehlo aphuzi noma isikhumba; ubuhlungu besisu; ukulinyazwa noma ukopha; ukulahlekelwa ukudla; umchamo ophuzi noma onsundu; indle ephaphathekile; noma ubuhlungu engxenyeni engaphezulu kwesokudla yesisu
• ukuqubuka
• ukuqubuka ngomkhuhlane noma ukulunywa
• amabhamuza noma isikhumba esixobukayo
• izilonda noma izilonda esikhumbeni, ezindebeni, noma emlonyeni

I-Umbralisib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-umbralisib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ukoniq^®