Inaliti ye-Evinacumab-dgnb

-Delile

• Ngaphambi kokuthola i-evinacumab-dgnb,
• I-Evinacumab-dgnb ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

I-Evinacumab-dgnb isetshenziswa ngokuhlangana nezinye izindlela zokwelapha ukunciphisa inani eliphansi le-lipoprotein (LDL) cholesterol ('cholesterol embi') nezinye izinto ezinamafutha egazini kubantu abadala kanye nezingane ezineminyaka engu-12 noma ngaphezulu ezine-homozygous family hypercholesterolemia (HoFH; isimo esizuzwe njengefa lapho i-cholesterol ingeke isuswe emzimbeni ngokujwayelekile). I-Evinacumab-dgnb isekilasini lemithi ebizwa nge-angiopoietin-like protein 3 (ANGPTL3) inhibitor monoclonal antibodies. Isebenza ngokunciphisa ukukhiqizwa kwe-cholesterol ye-LDL nokwandisa ukwehla kwe-cholesterol ye-LDL nezinye izinto ezinamafutha emzimbeni.

Ukuqoqeka kwe-cholesterol namafutha eceleni kwezindonga zemithambo (inqubo eyaziwa ngokuthi i-atherosclerosis) kunciphisa ukugeleza kwegazi, ngakho-ke, ukunikezwa komoya-mpilo enhliziyweni yakho, ebuchosheni nakwezinye izingxenye zomzimba wakho. Ukwehlisa izinga legazi lakho le-cholesterol namafutha kungasiza ekuvikeleni isifo senhliziyo, i-angina (ubuhlungu besifuba), imivimbo nokuhlaselwa yinhliziyo.

I-Evinacumab-dgnb iza njengesisombululo (uketshezi) ukuhlanganiswa noketshezi bese ujovwa kancane emthanjeni ngaphezu kwemizuzu engama-60 ngudokotela noma unesi. Imvamisa inikezwa kanye njalo emavikini amane.

Umjovo we-Evinacumab-dgnb ungadala ukusabela okukhulu ngesikhathi sokufakwa komuthi. Udokotela noma umhlengikazi uzokuqapha ngokucophelela ngenkathi uthola umuthi. Tshela udokotela wakho noma umhlengikazi ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi sokumnika noma ngemuva: ukuphefumula okuncane; ukushaya; ukuqubuka; isifuba; ukulunywa; isiyezi; ubuthakathaka bemisipha; imfiva; isicanucanu; ukucinana kwamakhala; noma ukuvuvukala kobuso, umphimbo, ulimi, izindebe, noma iso.

Udokotela wakho kungadingeka ukuthi anciphise ukumnika kwakho noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-evinacumab-dgnb.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-evinacumab-dgnb,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-evinacumab-dgnb, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-evinacumab-dgnb. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• utshele udokotela wakho uma ukhulelwe, noma uhlele ukukhulelwa. Ungadinga ukuthatha isivivinyo sokukhulelwa ngaphambi kokuqala ukwelashwa nge-evinacumab-dgnb. Akufanele ukhulelwe ngesikhathi sokwelashwa kwakho ngomjovo we-evinacumab-dgnb. Kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho ngomjovo we-evinacumab-dgnb nezinyanga ezi-5 ngemuva komthamo wakho wokugcina. Uma ukhulelwa ngenkathi uthola i-evinacumab-dgnb, shayela udokotela wakho ngokushesha.
• tshela udokotela wakho uma uncelisa.

Yidla ukudla okunamafutha aphansi, okunamafutha amancane. Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Ungavakashela iwebhusayithi ye-National Cholesterol Education Program (NCEP) ukuthola eminye imininingwane yokudla ku: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti ukuthola umthamo we-evinacumab-dgnb injection.

I-Evinacumab-dgnb ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhala eligijimayo
• ukuminyana kwamakhala
• Umphimbo obuhlungu
• izimpawu ezinjengomkhuhlane
• Umphimbo obuhlungu
• isiyezi
• isicanucanu
• ubuhlungu emilenzeni nasezingalweni
• amandla anciphile

I-Evinacumab-dgnb ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-evinacumab-dgnb.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Evkeeza^®