UBusulfan

-Delile

• Ngaphambi kokuthatha i-busulfan,
• I-Busulfan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Busulfan ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho wethambo. Tshela udokotela kanye nosokhemisi ngayo yonke imithi oyiphuzayo. Uma uthatha i-busulfan neminye imithi engadala ukubalwa kwegazi okuphansi, imiphumela emibi yemithi ingaba nzima kakhulu. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulinyazwa.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda ukuhlolwa kwelabhorethri ngaphambi, ngesikhathi nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-busulfan ukubona ukuthi amaseli akho egazi ayathinteka yini yilomuthi. Udokotela wakho angadinga ukushintsha umthamo wakho noma akutshele ukuthi uyeke ukuthatha i-busulfan isikhathi esithile ukuvumela ukubalwa kwegazi lakho kubuyele kokujwayelekile uma kwehle kakhulu. Landela izinkomba zikadokotela wakho ngokucophelela bese ubuza udokotela wakho uma ungazi ukuthi kufanele uthathe i-busulfan engakanani.

IBusulfan ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-busulfan.

I-Busulfan isetshenziselwa ukwelapha uhlobo oluthile lwe-leukemia engapheli (i-CML; uhlobo lomdlavuza wamaseli amhlophe egazi). UBusulfan usesigabeni semithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

IBusulfan iza njengethebhulethi yokuphuza ngomlomo kanye ngosuku. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo. Thatha i-busulfan ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-busulfan njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angalungisa umthamo wakho we-busulfan ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi oyitholayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha i-busulfan ngaphandle kokukhuluma nodokotela wakho.

Amaphilisi weBusulfan nawo asetshenziswa ngokuhlangana nezinye izidakamizwa ukubhubhisa umnkantsha kanye namaseli womdlavuza ukulungiselela ukufakelwa umnkantsha wethambo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-busulfan,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-busulfan, noma imuphi omunye umuthi, noma iziphi izithako kumaphilisi e-busulfan. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-acetaminophen (iTylenol); imishanguzo ethile yamakhemikhali efana ne-bendamustine (iTreanda), i-carmustine (i-BiCNU, i-Gliadel Wafer), i-cyclophosphamide (i-Cytoxan), ifosfamide (Ifex), lomustine (CeeNU), melphalan (Alkeran), procarbazine (Mutalane), temozolomide (Temodar), i-clozapine (Clozaril, FazaClo); i-cyclosporine (iSandimmune, iGengraf, Neoral); itraconazole (Sporanox); imithi yokugula ngengqondo kanye nesicanucanu; i-phenytoin (iDilantin); noma i-meperidine (i-Demerol). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-busulfan, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi wake wathola ukwelashwa ngemisebe noma ukwelashwa ngeminye imithi yokwelapha ngamakhemikhali noma uma uke waquleka noma walimala ekhanda. Phinda utshele udokotela wakho uma uke wathatha i-busulfan phambilini, kepha umdlavuza wakho awuphendulanga emithini.
• kufanele wazi ukuthi i-busulfan ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane, ingamisa ukukhiqizwa kwesidoda emadodeni. Kodwa-ke, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukusebenzisa lo muthi. Akufanele uhlele ukuba nezingane ngenkathi uthola i-chemotherapy noma isikhashana ngemuva kokwelashwa. (Khuluma nodokotela wakho ukuthola eminye imininingwane.) Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-busulfan, shayela udokotela wakho ngokushesha. IBusulfan ingalimaza umbungu.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Busulfan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isifo sohudo
• ukulahlekelwa isifiso sokudla noma isisindo
• ukuqunjelwa
• izilonda emlonyeni nasemphinjeni
• umlomo owomile
• ikhanda
• ubunzima bokulala noma ukulala
• uzizwe ukhathazeke ngokweqile noma ukhathazekile
• isiyezi
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ubuhlungu besifuba
• ubuhlungu obuhlangene, besisipha noma beqolo
• ukuqubuka kwesikhumba
• ukuluma nesikhumba esomile
• isikhumba esimnyama
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• emnyama, izitulo zokubambezeleka
• umchamo obomvu
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuphefumula kanzima
• izinguquko embonweni
• ukuhlanza
• ubuhlungu besisu
• isithuthwane

IBusulfan ingadala ukwehluleka kwe-ovari futhi ingavimba amantombazane ukuthi afinyelele ebusheni. Khuluma nodokotela wakho ngengozi yokungabi nenzalo ebangelwa yi-busulfan. Khuluma nodokotela wakho ngezingozi zokuthola lo muthi.

I-Busulfan ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• emnyama, izitulo zokubambezeleka
• umchamo obomvu
• ukulimaza noma ukopha okungavamile
• ukukhathala okungajwayelekile noma ubuthakathaka
• umphimbo obuhlungu, ukukhwehlela, umkhuhlane, noma ezinye izimpawu zokutheleleka
• isicanucanu
• ukuhlanza
• isifo sohudo
• izilonda emlonyeni nasemphinjeni

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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• IBusulphan