IChloroquine

-Delile

• Ngaphambi kokusebenzisa i-chloroquine phosphate,
• Imiphumela emibi evela ku-chloroquine phosphate ingenzeka. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Chloroquine ifundelwe ukwelashwa nokuvimbela isifo se-coronavirus 2019 (COVID-19).

I-FDA ivume Ukugunyazwa Kokusetshenziswa Okuphuthumayo (i-EUA) ngoMashi 28, 2020 ukuvumela ukusatshalaliswa kwe-chloroquine kubantu abadala nokwelashwa abanesisindo okungenani esingamakhilogremu ayi-50 futhi abangobani ungeniswe esibhedlela nge-COVID-19, kepha abangakwazi ukubamba iqhaza ocwaningweni lomtholampilo. Kodwa-ke, i-FDA yakukhansela lokhu ngoJuni 15, 2020 ngoba izifundo zomtholampilo zikhombisile ukuthi i-chloroquine akunakwenzeka ukuthi iphumelele ekwelapheni i-COVID-19 kulezi ziguli neminye imiphumela emibi, njengokushaywa kwenhliziyo okungajwayelekile kwabikwa.

I-FDA kanye neNational Institutes of Health (NIH) bathi i-chloroquine kufanele ithathwe KUPHELA ukuze yelashwe i-COVID-19 ngaphansi kokuqondisa kukadokotela ocwaningweni lomtholampilo. Ungathengi lo muthi online ngaphandle kwemithi kadokotela. Uma uhlangabezana nokushaya kwenhliziyo okungajwayelekile, isiyezi, noma ukuquleka ngenkathi uthatha i-chloroquine, shayela u-911 ukuthola ukwelashwa okuphuthumayo. Uma uneminye imiphumela emibi, qiniseka ukuthi utshela udokotela wakho.

Ungathathi i-chloroquine ehloselwe ukusetshenziswa kwezilwane - njengokulapha inhlanzi emanzini noma ukusetshenziswa kwezinye izilwane - ukwelapha noma ukuvimbela i-COVID-19. I-FDA ibika ukuthi ukulimala kanzima nokufa kuye kwabikwa kubantu abasebenzisa kabi la malungiselelo. https://bit.ly/2KpIMcR

I-chloroquine phosphate isetshenziselwa ukuvimbela nokwelapha umalaleveva. Ibuye isetshenziselwe ukwelapha i-amebiasis. I-chloroquine phosphate isesigabeni semithi ebizwa ngama-antimalarials kanye nama-amebicides. Isebenza ngokubulala izinto ezibanga umalaleveva kanye ne-amebiasis.

I-chloroquine phosphate iza njengethebhulethi yokuphuza ngomlomo. Ngokuvikela umalaleveva kubantu abadala, umthamo owodwa uvame ukuthathwa kanye ngesonto ngosuku olufanayo lwesonto. Udokotela wakho uzokutshela ukuthi mangaki amaphilisi ozowathatha ngomthamo ngamunye. Umthamo owodwa uthathwa ekuqaleni kwamasonto amabili ngaphambi kokuya endaweni lapho umkhuhlane we-malaria uvame khona, ngenkathi usendaweni, bese kuba amasonto ayi-8 ngemuva kokubuya endaweni. Uma ungakwazi ukuqala ukuthatha i-chloroquine amasonto amabili ngaphambi kokuhamba, udokotela wakho angakutshela ukuthi uthathe umthamo ophindwe kabili ngokushesha (ngomthamo wokuqala).

Ekwelapheni ukuhlaselwa ngamandla kukamalaleveva kubantu abadala, kuvame ukuthatha umthamo owodwa zisuka nje, kulandelwe uhhafu womthamo amahora ayisithupha kuya kwayisishiyagalombili kamuva bese uhhafu womthamo kanye ngosuku ngezinsuku ezi-2 ezilandelayo.

Ngokuvikela nokwelashwa kukamalaleveva ezinganeni nasezinganeni, inani le-chloroquine phosphate lisuselwa esisindweni sengane. Udokotela wakho uzobala le mali bese ekutshela ukuthi ingakanani i-chloroquine phosphate ingane yakho okufanele ayithole.

Ukwelashwa kwe-amebiasis, umthamo owodwa uvame ukuthathwa izinsuku ezimbili bese uhhafu womthamo nsuku zonke amasonto amabili kuya kwamathathu. Imvamisa ithathwa ihlanganiswe namanye ama-amebicides.

I-chloroquine phosphate ingadala isisu esibuhlungu. Thatha i-chloroquine phosphate ngokudla.

Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-chloroquine phosphate njengoba nje uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

I-chloroquine phosphate isetshenziswa ngezikhathi ezithile ukwehlisa izimpawu zesifo samathambo nokwelapha i-lupus erythematosus, i-sarcoidosis ne-porphyria cutanea tarda. Khuluma nodokotela wakho ngezingozi ezingenzeka zokusebenzisa lesi sidakamizwa ngesimo sakho.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-chloroquine phosphate,

• Tshela udokotela kanye nosokhemisi wakho uma ungenwe i-chloroquine phosphate, i-chloroquine hydrochloride, i-hydroxychloroquine (i-Plaquenil), noma enye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho i-acetaminophen (iTylenol, abanye); i-azithromycin (iZithromax); i-cimetidine (Tagamet); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-insulin nemithi yomlomo yesifo sikashukela; imishanguzo yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), noma i-valproic acid (Depakene); imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Pacerone); i-methotrexate (Trexall, Xatmep); moxifloxacin (Avelox); i-praziquantel (i-Biltricide); kanye ne-tamoxifen (Nolvadex). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-chloroquine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• uma uthatha ama-antacids, thatha amahora amane ngaphambi noma ngemuva kwamahora amane ngemuva kwe-chloroquine. Uma uthatha i-ampicillin, yithathe okungenani amahora amabili ngaphambi noma amahora amabili ngemuva kwe-chloroquine.
• Tshela udokotela wakho uma uke waba nesifo sesibindi, isifo senhliziyo, isikhawu se-QT eside (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe), ukushaya kwenhliziyo okungajwayelekile, izinga eliphansi le-magnesium noma i-potassium igazi lakho, ukuntuleka kwe-G-6-PD (isifo segazi esizuzwe njengefa), izinkinga zokuzwa, i-porphyria noma ezinye izifo zegazi, i-psoriasis, ukuqubuka, izinkinga zokubona, isifo sikashukela, ubuthakathaka emadolweni nasemaqakaleni, noma uma uphuza kakhulu utshwala.
• Tshela udokotela wakho uma wake waba nezinguquko zombono ngenkathi uthatha i-chloroquine phosphate, chloroquine hydrochloride, noma i-hydroxychloroquine (Plaquenil).
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi usebenzisa i-chloroquine phosphate, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa noma uhlela ukuncelisa. I-Chloroquine phosphate ingalimaza usana olusancelayo.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akuyalele ngenye indlela, qhubeka nokudla okujwayelekile ngenkathi uthatha i-chloroquine phosphate.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Imiphumela emibi evela ku-chloroquine phosphate ingenzeka. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isicanucanu
• ukulahlekelwa isifiso sokudla
• isifo sohudo
• isisu esibuhlungu
• ubuhlungu besisu
• ukuqubuka
• ukulunywa
• ukulahleka kwezinwele

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

• ukubona ukukhanya okukhanyayo nemichilo
• ukungaboni kahle
• ukufunda noma ukubona ubunzima (amagama ayanyamalala, ukubona uhhafu wento, umbono onenkungu noma wenkungu)
• kunzima ukuzwa
• kukhala ezindlebeni
• ubuthakathaka bemisipha
• ukozela
• ukuhlanza
• ukushaya kwenhliziyo okungajwayelekile
• ukudlikizela
• ukuphefumula kanzima
• ukushintsha kwemizwelo noma kwengqondo
• kwehle ukwazi noma ukulahlekelwa ukwazi
• ucabanga ngokuzilimaza noma ukuzibulala

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kude nokukhanya nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu
• ukuhlanza
• ikhanda
• ukozela
• ukuphazamiseka okubukwayo
• ukudlikizela
• ukushaya kwenhliziyo okungajwayelekile

Izingane zizwela kakhulu ukweqisa izidakamizwa, ngakho-ke gcina umuthi lapho izingane zingafinyeleli kuwo.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu kanye nama-electrocardiograms (EKG, isivivinyo sokuqapha izinga lokushaya kwenhliziyo yakho nesigqi) ukuhlola impendulo yakho ku-chloroquine phosphate. Udokotela wakho uzophinde avivinye ingqondo yakho ukuze abone ukuthi ngabe unobuthakathaka bemisipha obungabangelwa yisidakamizwa.

Uma uthatha i-chloroquine phosphate isikhathi eside, udokotela wakho uzoncoma izivivinyo zamehlo njalo. Kubaluleke kakhulu ukuthi ugcine lezi zikhundla. I-chloroquine phosphate ingadala izinkinga ezinkulu zokubona. Uma uhlangabezana nanoma yiziphi izinguquko embonweni, yeka ukuthatha i-chloroquine phosphate bese ushayela udokotela wakho ngokushesha.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Aralen^®¶

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.