I-Etidronate

-Delile

• I-Etidronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu exhuma umlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwanga ngokwemiyalo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:
• Ngaphambi kokuthatha i-etidronate,
• I-Etidronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Etidronate isetshenziselwa ukwelapha isifo samathambo sikaPaget (isimo lapho amathambo ethambe khona futhi ebuthakathaka futhi engahle akhubazeke, abebuhlungu, noma aphuke kalula) nokuvikela nokwelapha i-heterotopic ossification (ukukhula kwamathambo ethambo endaweni yomzimba ukwedlula amathambo) kubantu asebeke bahlinzwa ngokuphelele (esikhundleni sokuhlinzwa esikhundleni sokuhlangana kwe-hip nejoyinti lokufakelwa) noma kubantu abalimele umgogodla. I-Etidronate isekilasini lemithi ebizwa ngama-bisphosphonates. Isebenza ngokunciphisa ukubola kwethambo elidala nokwakhiwa kwethambo elisha.

I-Etidronate iza njengethebhulethi ukuyithatha ngomlomo. Kuvame ukuthathwa kanye ngosuku esiswini esingenalutho. Ukwelashwa kwesifo sikaPaget kungaphindwa uma izimpawu zibuya noma ziba zimbi kakhulu ngemuva kwesikhathi esithile. Thatha i-etidronate ngasikhathi sinye (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-etidronate njengoba iqondisiwe. Ungayithathi ngaphezulu noma ngaphansi kwayo noma uyithathe kaningi noma isikhathi eside kunokuyalelwa ngudokotela wakho.

I-Etidronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu exhuma umlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwanga ngokwemiyalo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:

• Gwinya amathebulethi ngengilazi egcwele (amamitha ayi-180 kuye kwayi-240) wamanzi angenalutho ngenkathi uhleli noma umile.
• Hlala noma ume mpo ngemuva kokuthatha i-etidronate.
• Ungadli, ungaphuzi, noma uthathe noma imuphi omunye umuthi (kufaka phakathi amavithamini noma ama-antacids) amahora amabili ngaphambili kanye namahora amabili ngemuva kokuthatha i-etidronate.

Uma uthatha i-etidronate ukwelapha isifo sePaget samathambo noma ukuvimbela noma ukwelapha i-heterotopic ossification, kungathatha isikhathi ukuthi isimo sakho sithuthuke. Ungayeki ukuthatha i-etidronate ngaphandle kokukhuluma nodokotela wakho.

I-Etidronate nayo iyasetshenziswa kwesinye isikhathi ukwelapha nokuvikela i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi angahle aphuke kalula) okubangelwa i-corticosteroids (uhlobo lomuthi ongadala i-osteoporosis). Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-etidronate,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-etidronate, noma imiphi eminye imithi, noma iziphi izithako ezikumathebulethi e-etidronate. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: i-angiogenesis inhibitors efana ne-bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), noma sunitinib (Sutent); ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); i-chemotherapy yomdlavuza; kanye ne-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha izithasiselo zamavithamini nezamaminerali njenge-iron, noma uma uthatha ama-antacids aqukethe i-calcium, i-magnesium, noma i-aluminium (Maalox, Mylanta, Tums, others), thatha amahora amabili ngaphambi noma amahora amabili ngemuva kokuthatha i-etidronate.
• Tshela udokotela wakho uma uke waba nezinkinga nge-esophagus yakho njengokuqina kokuqina (ukunciphisa isopha okubangela ubunzima bokugwinya) noma i-achalasia (ukuphazamiseka okuthinta ikhono lomphimbo wokuhambisa ukudla uye esiswini), noma i-osteomalacia (ukuthambisa amathambo ngenxa yokushoda kwamaminerali). Udokotela wakho angakutshela ukuthi ungathathi i-etidronate.
• tshela udokotela wakho uma ungakwazi ukuhlala noma ukuma mpo futhi uma uke waba nayo noma wake waba ne-anemia (isimo lapho amangqamuzana abomvu egazi engalethi umoya-mpilo owenele kuzo zonke izingxenye zomzimba); izinga eliphansi le-calcium egazini lakho; ubunzima bokugwinya, isilungulela, izilonda, noma ezinye izinkinga zesisu; umdlavuza; i-enterocolitis (ukuvuvukala emathunjini); noma yiluphi uhlobo lokutheleleka, ikakhulukazi emlonyeni wakho; izinkinga ngomlomo wakho, ngamazinyo, noma ngezinsini; noma isiphi isimo esivimba igazi lakho ekunqandeni ngokujwayelekile; noma isifo sezinso. Udokotela wakho angadinga ukushintsha umthamo wemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Phinda utshele udokotela wakho uma uhlela ukukhulelwa nganoma yisiphi isikhathi ngokuzayo ngoba i-etidronate ingahlala emzimbeni wakho iminyaka ngemuva kokuyeka ukuyithatha. Shayela udokotela wakho uma ukhulelwa ngesikhathi noma ngemuva kokwelashwa kwakho nge-etidronate.
• kufanele wazi ukuthi i-etidronate ingadala i-osteonecrosis yomhlathi (i-ONJ, isimo esibi sethambo lomhlathi), ikakhulukazi uma uhlinzwa noma ukwelashwa ngenkathi uthatha umuthi. Udokotela wamazinyo kufanele ahlole amazinyo akho futhi enze noma yiziphi izindlela zokwelashwa ezidingekayo, kufaka phakathi ukuhlanza noma ukulungisa amazinyo okufakelwa angalungile, ngaphambi kokuba uqale ukuthatha i-etidronate. Qiniseka ukuthi uxubha amazinyo futhi uhlanza umlomo wakho kahle ngenkathi uthatha i-etidronate. Khuluma nodokotela wakho ngaphambi kokuthola noma yikuphi ukwelashwa kwamazinyo ngenkathi uthatha lo muthi.
• kufanele wazi ukuthi i-etidronate ingadala ubuhlungu obukhulu bethambo, imisipha, noma amalunga. Ungaqala ukuzwa lobu buhlungu kungakapheli izinsuku, izinyanga, noma iminyaka ngemuva kokuthatha i-etidronate. Yize lolu hlobo lobuhlungu lungaqala ngemuva kokuthi uthathe i-etidronate isikhathi esithile, kubalulekile ukuthi wena nodokotela wakho nazi ukuthi kungabangelwa yi-etidronate. Shayela udokotela wakho ngokushesha uma uzwa ubuhlungu obukhulu noma kunini ngesikhathi sokwelashwa kwakho nge-etidronate. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-etidronate futhi ubuhlungu bakho bungaphela ngemuva kokuyeka ukuthatha umuthi.

Kubalulekile ukuthi uthole i-calcium eyanele novithamini D futhi udle ukudla okunomsoco ngenkathi uthatha i-etidronate. Udokotela wakho uzokutshela ukuthi yikuphi ukudla okuyimithombo emihle yalezi zinongo nokuthi zingaki izinsizakalo ozidingayo usuku ngalunye. Uma ukuthola kunzima ukudla okwanele kulokhu kudla, tshela udokotela wakho. Uma kunjalo, udokotela wakho angakunikeza noma ancome ukuthi kufakwe isengezo.

Uma ungakadli, thatha umthamo owulahlekile ngokushesha uma uwukhumbula. Uma usudlile vele, thatha umthamo ongabanjwanga emahoreni amabili ngemuva kokugcina ukudla. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Etidronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

• isilungulela esisha noma esiba sibi kakhulu
• ubuhlungu lapho ugwinya
• ubuhlungu besifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ubunzima bokugwinya
• amabhamuza esikhunjeni

I-Etidronate ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuhlanza
• amajaqamba esiswini
• isifo sohudo
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni
• ukuphazamiseka kwemisipha namajaqamba

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-etidronate.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Didronel^®

• I-EHDP