I-Spironolactone

-Delile

• Ngaphambi kokuthatha i-spironolactone,
• I-Spironolactone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Spironolactone ibangele izicubu ezilwaneni zaselebhu. Khuluma nodokotela wakho ngezingozi nezinzuzo zokusebenzisa lo muthi ngesimo sakho.

I-Spironolactone isetshenziselwa ukwelapha iziguli ezithile ezine-hyperaldosteronism (umzimba ukhiqiza i-aldosterone eningi kakhulu, i-hormone eyenzeka ngokwemvelo); amazinga aphansi e-potassium; ukwehluleka kwenhliziyo; nasezigulini ezine-edema (ukugcinwa koketshezi) okudalwa yizimo ezahlukahlukene, kufaka phakathi isibindi, noma isifo sezinso. Ibuye isetshenziswe yodwa noma neminye imithi yokwelapha umfutho wegazi ophakeme. ISpironolactone isekilasini lemithi ebizwa ngama-aldosterone receptor antagonists. Kubangela izinso ukususa amanzi angadingeki kanye ne-sodium emzimbeni kuya emchameni kepha kunciphise ukulahleka kwe-potassium emzimbeni.

Umfutho wegazi ophezulu yisimo esivamile futhi uma ungelashwa, ungadala umonakalo ebuchosheni, enhliziyweni, emithanjeni yegazi, ezinso nakwezinye izingxenye zomzimba. Ukulimala kwalezi zitho kungadala isifo senhliziyo, isifo senhliziyo, ukwehluleka kwenhliziyo, isifo sohlangothi, ukwehluleka kwezinso, ukungaboni, nezinye izinkinga. Ngaphezu kokuthatha umuthi, ukwenza ushintsho endleleni ophila ngayo kuzosiza nasekulawuleni umfutho wegazi. Lezi zinguquko zifaka phakathi ukudla ukudla okunamafutha nosawoti omncane, ukugcina isisindo esinempilo, ukuzivocavoca okungenani imizuzu engama-30 izinsuku eziningi, ukungabhemi, nokusebenzisa utshwala ngokulinganisela.

ISpironolactone iza njengethebhulethi nokumiswa (uketshezi; iCarospir) ukuthatha ngomlomo. Imvamisa kuthathwa kanye noma kabili ngosuku. Thatha ukumiswa kwe-spironolactone ngokungaguquki ngokudla noma ngaphandle kokudla isikhathi ngasinye. Thatha i-spironolactone cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-spironolactone njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Shake ukumiswa ngomlomo kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo.

Udokotela wakho angakuqala ngomthamo ophansi we-spironolactone futhi akhuphule kancane umthamo wakho.

Amaphilisi e-Spironolactone nokumiswa kukhipha umuthi ngendlela ehlukile emzimbeni wakho futhi akunakushintshwa kufakwe omunye komunye. Thatha kuphela umkhiqizo we-spironolactone obekwe udokotela wakho futhi ungashintsheli komunye umkhiqizo we-spironolactone ngaphandle kokuthi udokotela wakho athi kufanele.

ISpironolactone ilawula umfutho wegazi ophakeme, i-edema, ukwehluleka kwenhliziyo, ne-hyperaldosteronism kepha ayizelaphi lezi zimo. Kungathatha cishe amasonto ama-2 noma ngaphezulu ngaphambi kokuba umphumela ogcwele we-spironolactone uvele. Qhubeka uthathe i-spironolactone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-spironolactone ngaphandle kokukhuluma nodokotela wakho.

I-Spironolactone nayo iyasetshenziswa ihlangene neminye imithi ukwelapha ukuthomba kokuthomba (isimo esenza ukuthi izingane zingene ebusheni ngokushesha kakhulu, okuholela ekwakhiweni kwezici zobulili emantombazaneni ngokuvamile angaphansi kweminyaka eyi-8 futhi kubafana ngokuvamile abangaphansi kweminyaka engu-9 ubudala ) noma i-myasthenia gravis (i-MG, isifo lapho izinzwa zingasebenzi kahle futhi iziguli zingathola ubuthakathaka; ukuba ndikindiki; ukulahleka kokuhlangana kwemisipha; nezinkinga ngombono, ukukhuluma, nokulawula isinye). I-Spironolactone nayo ingasetshenziselwa ukwelapha iziguli ezithile zesifazane ngezinwele zobuso ezingavamile. Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-spironolactone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-spironolactone; noma imiphi eminye imithi; noma yiziphi izithako ezibhebheni ze-spironolactone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• utshele udokotela wakho uma uthatha i-eplerenone (Inspra). Udokotela wakho angakutshela ukuthi ungathathi i-spironolactone uma uthatha lo muthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: ama-antibiotic e-aminoglycoside afana ne-amikacin, i-gentamicin, i-kanamycin, i-neomycin (i-Neo-Rx, i-Neo-Fradin), i-streptomycin, ne-tobramycin (i-Tobi); i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin, eLotrel), captopril (Capoten), enalapril (Vasotec), fosinopril, lisinopril (ePrinzide, eZestoretic), moexipril (Univasc, in Uniretic) Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kanye ne-trandolapril (Mavik, eTarka); abamelene ne-angiotensin II (ama-angiotensin receptor blockers; ama-ARB) anjenge-azilsartan (i-Edarbi, i-Edarbyclor), i-candesartan (i-Atacand, e-Atacand HCT), i-eprosartan (iTeveten, eTeveten HCT), irbesartan (Avapro, e-Avalide), losartan (Cozaar) IHyzaar), olmesartan (Benicar, e-Azor, Benicar HCT, Tribenzor), telmisartan (Micardis, eMicardis HCT), kanye ne-valsartan (Diovan, eDiovan HCT, Exforge); i-aspirin neminye imishanguzo yokulwa nokuvuvukala (i-NSAIDS) efana ne-ibuprofen (Advil, Motrin), indomethacin (Indocin, Tivorbex), ne-naproxen (Aleve, Naprosyn); ama-barbiturates afana ne-phenobarbital; cholestyramine (Prevalite); i-cisplatin; i-digoxin (i-Lanoxin); ama-diuretics ('amaphilisi amanzi') afaka i-potassium-sparing diuretics efana ne-amiloride (Midamor) ne-triamterene (Dyrenium, eDyazide, eMaxzide); i-heparin noma i-hematin enoxaparin enesisindo esiphansi (i-Lovenox); i-lithium (i-Lithobid); imithi yokwelapha umfutho wegazi ophakeme; imithi ye-narcotic yezinhlungu; i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); izithako ze-potassium; futhi trimethoprim (Primsol, e Bactrim).
• tshela udokotela wakho uma unesifo i-Addison noma ezinye izimo ezingadala amazinga aphezulu egazi e-potassium, noma isifo sezinso. Udokotela wakho angakutshela ukuthi ungathathi i-spironolactone.
• tshela udokotela wakho uma unesifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, noma uhlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-spironolactone, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-spironolactone.
• kufanele wazi ukuthi ukuphuza utshwala ngalo muthi kungadala isizungu, ikhanda elincane, nokuquleka lapho uvuka masinyane usuka endaweni elele. Khuluma nodokotela wakho ngokuphuza utshwala ngenkathi uthatha i-spironolactone.

Landela izinkomba zikadokotela wakho ngokudla kwakho, kufaka phakathi izeluleko zokudla okunosawoti owehlisiwe (uhlelo lwe-sodium) nohlelo lokuzivocavoca nsuku zonke. Gwema okufakwa esikhundleni sikasawoti esiqukethe i-potassium ngenkathi uthatha lo muthi. Khuluma nodokotela wakho ngenani lokudla okunothe nge-potassium (isb., Ubhanana, umlimi unquma, omisiwe nejusi le-orange) ongaba nakho ekudleni kwakho.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Spironolactone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuhlanza
• isifo sohudo
• ubuhlungu besisu noma amajaqamba
• amabele akhulisiwe noma abuhlungu kwabesilisa noma kwabesifazane
• izikhathi ezingajwayelekile zokuya esikhathini
• ukuphuma kwesitho sangasese sowesifazane ngemuva kokuya esikhathini ('ngemuva kokushintsha kwempilo', ukuphela kwezikhathi zokuya esikhathini njalo ngenyanga) abesifazane
• ubunzima bokugcina noma ukufeza ukwakhiwa
• ukujula kwezwi
• ukukhula kwezinwele okukhulayo ezingxenyeni zomzimba
• ukozela
• ukukhathala
• ukungahlaliseki

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuthakathaka bemisipha, ubuhlungu, noma amajaqamba
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni
• ukungakwazi ukuhambisa izingalo noma imilenze
• izinguquko ekushayeni kwenhliziyo
• ukudideka
• isicanucanu
• ukukhathala ngokweqile
• umlomo owomile, ukoma, isiyezi, ukungaqiniseki, ikhanda elibuhlungu, noma ezinye izimpawu zokoma
• ukopha okungajwayelekile noma ukulinyazwa
• ukungabi namandla
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuhlanza igazi
• igazi ezindlini
• ukuncipha kokuchama
• ukuquleka

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina lo muthi esitsheni owangena ngawo, uvalwe waqina, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukozela
• ukudideka
• ukuqubuka
• isicanucanu
• ukuhlanza
• isiyezi
• isifo sohudo
• ukuluma ezingalweni nasemilenzeni
• ukulahleka kwethoni yemisipha
• ubuthakathaka noma ubunzima emilenzeni
• ukushaya kwenhliziyo okungajwayelekile noma okuhamba kancane

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-spironolactone.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-spironolactone.

Ungavumeli omunye umuntu athathe umuthi wakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Aldactone^®
• ICarospir^®