Inaliti ye-Fluorouracil

-Delile

• Ngaphambi kokuthola i-fluorouracil,
• I-Fluorouracil ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-fluorouracil kufanele unikezwe esibhedlela noma esikhungweni sezokwelapha ngaphansi kweso likadokotela onolwazi lokunikeza imishanguzo yamakhemikhali yomdlavuza. Ukwelashwa ngomjovo we-fluorouracil kungadala imiphumela emibi kakhulu.

I-Fluorouracil ivame ukusetshenziswa ngokuhlanganiswa neminye imithi yokwelapha umdlavuza we-colon noma umdlavuza we-rectal (umdlavuza oqala emathunjini amakhulu) osekubi kakhulu noma usakazeka kwezinye izingxenye zomzimba. I-Fluorouracil isetshenziswa ngokuhlangana neminye imithi yokwelapha izinhlobo ezithile zomdlavuza webele ngemuva kokuhlinzwa ukususa isimila noma i-radiation therapy. I-Fluorouracil isetshenziselwa ukwelapha umdlavuza wamanyikwe nomdlavuza wesisu. I-Fluorouracil isekilasini lemithi ebizwa ngama-antimetabolites. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

Umjovo we-fluorouracil uza njengesisombululo (uketshezi) okufanele unikezwe ngemithambo (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma ushintshe umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa ngomjovo we-fluorouracil.

I-Fluorouracil kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza wesibeletho (ukuvulwa kwesibeletho) nomphimbo, umdlavuza wekhanda nowentamo (kubandakanya umdlavuza womlomo, udebe, isihlathi, ulimi, ulwanga, umphimbo, amalaka nezinsimbi), umdlavuza wesibeletho ( umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda), nomdlavuza wesifo sezinso (RCC, uhlobo lomdlavuza oqala ezinso). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-fluorouracil,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-fluorouracil noma ezinye izithako zomjovo we-fluorouracil. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imishanguzo ethile ye-chemotherapy efana ne-bendamustine (Treanda), busulfan (Myerlan, Busulfex), carmustine (BiCNU, Gliadel Wafer), cyclophosphamide (Cytoxan), chlorambucil (Leukeran), ifosfamide (Ifex), lomustine (CeeNU), melphalan (Alkeran), procarbazine (Mutalane), noma temozolomide (Temodar); imishanguzo ecindezela amasosha omzimba njenge-azathioprine (Imuran), i-cyclosporine (i-Neoral, iSandimmune), i-methotrexate (i-Rheumatrex), i-sirolimus (i-Rapamune), ne-tacrolimus (i-Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma unesifo. Udokotela wakho kungenzeka angafuni ukuthi uthole umjovo we-fluorouracil.
• utshele udokotela wakho ukuthi wake wakuthola ukwelashwa ngemisebe (x-ray) noma ukwelashwa ngeminye imithi yokwelapha ngamakhemikhali noma uma uke waba nesifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola umjovo we-fluorouracil. Uma ukhulelwa ngenkathi uthola umjovo we-fluorouracil, shayela udokotela wakho. I-Fluorouracil ingalimaza umbungu.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga. I-Fluorouracil ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Fluorouracil ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukukhathala okungajwayelekile noma ubuthakathaka
• isiyezi
• ikhanda
• ukulahleka kwezinwele
• isikhumba esomile futhi esiqhekekile
• umbono uyashintsha
• iso elikhalayo noma elizwelayo ekukhanyeni
• ububomvu, ubuhlungu, ukuvuvukala, noma ukushisa endaweni lapho umjovo wanikezwa khona
• ukudideka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• izilonda emlonyeni nasemphinjeni
• isifo sohudo
• ukuhlanza
• ukuvuvukala, ubuhlungu, ubomvu, noma ukuxebuka kwesikhumba ezintendeni zezandla nasematheni ezinyawo
• umkhuhlane, amakhaza, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuphuma kwamakhala
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• ukopha okungajwayelekile noma ukulinyazwa
• umchamo obomvana, obomvu, noma onsundu
• okubomvu noma okulindile ukunyakaza kwamathumbu amnyama
• ubuhlungu besifuba

I-Fluorouracil ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• isifo sohudo
• ukuhlanza
• umkhuhlane, amakhaza, umphimbo obuhlungu, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• ezinegazi noma ezimnyama, izitulo zokulinda
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi

Gcina onke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri Udokotela wakho uzothumela / anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-fluorouracil.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Adrucil^® Ukujova^¶

• I-5-Fluorouracil
• 5-FU

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.