Ukujova kweCisplatin

-Delile

• Ngaphambi kokuthatha i-cisplatin,
• I-Cisplatin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo we-Cisplatin kufanele unikezwe esibhedlela noma esikhungweni sezokwelapha ngaphansi kweso likadokotela onolwazi lokunikeza imithi yamakhemikhali yokwelashwa komdlavuza.

I-Cisplatin ingadala izinkinga ezinkulu zezinso. Izinkinga zezinso zingenzeka kaningi kubantu asebekhulile. Udokotela wakho uzo-oda ukuhlolwa kwelabhorethri ngaphambi nangesikhathi sokwelashwa kwakho ukubona ukuthi izinso zakho ziyathinteka yini yile mithi. Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso. Tshela udokotela kanye nosokhemisi wakho uma uthatha ama-antibiotic e-aminoglycoside afana ne-amikacin (Amikin), i-gentamicin (Garamycin), noma i-tobramycin (i-Tobi, i-Nebcin). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuncipha kokuchama; ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukukhathala okungajwayelekile noma ubuthakathaka.

I-Cisplatin ingadala izinkinga ezinkulu zokuzwa, ikakhulukazi ezinganeni. Ukulahlekelwa kokuzwa kungahlala unomphela kwezinye izimo. Udokotela wakho uzo-oda izivivinyo ukuqapha ukuzwa kwakho ngaphambi nangesikhathi sokwelashwa kwakho. Tshela udokotela wakho kanye nosokhemisi uma ngabe uke welashwa ngemisebe ekhanda lakho. Tshela udokotela kanye nosokhemisi wakho uma uthatha ama-antibiotic e-aminoglycoside afana ne-amikacin (Amikin), i-gentamicin (Garamycin), noma i-tobramycin (i-Tobi, i-Nebcin). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukulahlekelwa ukuzwa, ukukhala ezindlebeni, noma isiyezi.

I-Cisplatin ingadala ukusabela okweqile komzimba, ikakhulukazi uma uthole umthamo ongaphezu koyedwa womjovo we-cisplatin.Uma uhlangabezana nokungezwani komzimba nomjovo we-cisplatin, kungaqala kungakapheli imizuzu embalwa ngemuva kokufakwa kwakho, futhi ungathola lezi zimpawu ezilandelayo: isifuba; ukuqubuka kwesikhumba; ukulunywa; ukubomvu kwesikhumba; ubunzima bokuphefumula noma ukugwinya; ukuvuvukala kobuso, umphimbo, ulimi, izindebe; isiyezi; ukuquleka; noma ukushaya kwenhliziyo okusheshayo. Tshela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi, ngesikhathi, nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-cisplatin. Udokotela wakho angadinga ukuyeka noma ukubambezela ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi.

I-Cisplatin isetshenziswa ukuhlanganiswa neminye imishanguzo yokwelapha umdlavuza wamasende ongakathuthuki noma osekubi kakhulu ngemuva kokwelashwa ngeminye imishanguzo noma i-radiation therapy. I-Cisplatin isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwelapha umdlavuza wama-ovari (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda) okungakathuthuki noma okuye kwaba kubi kakhulu ngemuva kokwelashwa ngeminye imishanguzo noma ngemisebe yelanga. I-Cisplatin nayo isetshenziswa yodwa noma ihlanganiswe neminye imishanguzo yokwelapha umdlavuza wesinye ongeke welashwe ngokuhlinzwa noma ngemisebe yelashwa kuphela. I-Cisplatin isekilasini lemithi eyaziwa ngokuthi i-platinum compounds. Isebenza ngokumisa noma ukunciphisa ukukhula kwamangqamuzana omdlavuza.

Umjovo weCisplatin uza njengesisombululo (uketshezi) esizofakwa ngaphezu kwamahora ayisithupha kuya kwayisishiyagalombili ngemithambo (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa inikezwa kanye njalo emavikini ama-3 kuye kwayi-4.

I-Cisplatin kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza wekhanda nowentamo (kufaka phakathi umdlavuza womlomo, udebe, isihlathi, ulimi, ulwanga, umphimbo, amalaka, nezinsimbi), umdlavuza wamaphaphu, umdlavuza womlomo wesibeletho kanye nomphimbo, izicubu zobuchopho, i-mesothlioma ebabayo (umdlavuza emgqeni wesifuba noma wesisu), ne-neuroblastoma (umdlavuza oqala kumaseli ezinzwa futhi uvele ikakhulukazi ezinganeni). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-cisplatin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cisplatin, carboplatin (Paraplatin), noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-cisplatin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SEXWAYISO nakokulandelayo: i-amphotericin B (i-Abelcet; i-AmBisome; i-Amphotec, i-Fungizone Intravenous), ama-anticonvulsants afana ne-phenytoin (Dilantin), i-bumetanide (i-Bumex), i-ethacrynic acid (i-Edecrin), i-furosemide (i-Lasix), i-pyridoxine (i-Vitamin B-6). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-cisplatin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• tshela udokotela wakho uma unesifo sezinso noma unenkinga yokuzwa. Udokotela wakho kungenzeka angafuni ukuthi uthole umjovo we-cisplatin.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola i-cisplatin. Uma ukhulelwa ngenkathi uthola i-cisplatin, shayela udokotela wakho. I-Cisplatin ingalimaza umbungu.

I-Cisplatin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukulahleka kwezinwele
• ukulahlekelwa amandla okunambitha ukudla
• izinqa
• umlomo owomile, umchamo omnyama, ukuncipha kokujuluka, isikhumba esomile, nezinye izimpawu zokoma

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuvuvukala, ubuhlungu, ubomvu, noma ukushisa endaweni yomjovo
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• amajaqamba
• ukuhamba kanzima
• umuzwa wokwethuka okufana nogesi lapho ugoba intamo yakho phambili
• isithuthwane
• izinguquko ezingazelele embonweni, kufaka phakathi umbala
• ukulahleka kombono
• ubuhlungu beso
• ubuhlungu besifuba noma ingcindezi
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza okunegazi
• okokuhlanza okubukeka njengezizathu zekhofi

I-Cisplatin ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

I-Cisplatin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuncipha kokuchama
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• isicanucanu
• ukuhlanza
• ukopha okungajwayelekile noma ukulinyazwa
• izinkinga zokuzwa
• izinguquko ezingazelelwe embonweni
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Platinol^®¶
• IPlatinol-AQ^®¶

• i-cis-DDP
• i-cis-Diamminedichloroplatinum
• i-cis-Platinum II
• I-DDP

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.