Ukujova kwe-cyclosporine

-Delile

• Ngaphambi kokuthola umjovo we-cyclosporine,
• Umjovo we-cyclosporine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

Umjovo we-cyclosporine kufanele unikezwe ngaphansi kweso likadokotela onolwazi lokwelapha ukufakelwa kweziguli nokubeka imishanguzo eyehlisa ukusebenza kwamasosha omzimba.

Ukuthola umjovo we-cyclosporine kungakhuphula ubungozi bokuthi uzoba nokutheleleka noma umdlavuza, ikakhulukazi i-lymphoma (umdlavuza wengxenye yamasosha omzimba) noma umdlavuza wesikhumba. Le ngozi ingaphakama uma uthola umjovo we-cyclosporine neminye imithi eyehlisa ukusebenza kohlelo lomzimba njenge-azathioprine (Imuran), i-chemotherapy yomdlavuza, i-methotrexate (i-Rheumatrex), i-sirolimus (i-Rapamune), ne-tacrolimus (i-Prograf). Tshela udokotela wakho uma ngabe uthatha noma iyiphi yale mithi, nokuthi ngabe uke waba nanoma iluphi uhlobo lomdlavuza noma wake waba nalo. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umphimbo obuhlungu, umkhuhlane, ukubanda, nezinye izimpawu zokutheleleka; izimpawu ezinjengomkhuhlane; ukukhwehlela; ubunzima bokuchama; ubuhlungu lapho uchama; indawo ebomvu, ephakanyisiwe, noma evuvukile esikhunjeni; izilonda ezintsha noma ukushintsha kombala esikhunjeni; izigaxa noma uquqaba noma kuphi emzimbeni wakho; ukujuluka ebusuku; izindlala ezivuvukile entanyeni, emakhwapheni, noma emgodini; ukuphefumula kanzima; ubuhlungu besifuba; ubuthakathaka noma ukukhathala okungapheli; noma ubuhlungu, ukuvuvukala, noma ukugcwala esiswini.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-cyclosporine.

Umjovo we-cyclosporine usetshenziswa neminye imithi ukuvimbela ukwenqatshwa kokufakelwa (ukuhlaselwa kwesitho esifakelwe amasosha omzimba womuntu othola isitho) kubantu abathole ukufakelwa izinso, isibindi, nenhliziyo. Umjovo we-cyclosporine kufanele usetshenziselwe kuphela ukwelapha abantu abangakwazi ukuthatha i-cyclosporine ngomlomo. ICyclosporine isekilasini lemithi ebizwa ngama-immunosuppressants. Isebenza ngokunciphisa umsebenzi wamasosha omzimba.

Umjovo we-cyclosporine uza njengesisombululo (uketshezi) sokujovwa ngaphezu kwamahora amabili kuya kwayisithupha emthanjeni, imvamisa udokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa amahora ayi-4 kuye kwayi-12 ngaphambi kokuhlinzwa kokufakelwa kanye kanye ngosuku ngemuva kokuhlinzwa kuze kuthathwe imithi ngomlomo.

Udokotela noma umhlengikazi uzokubuka eduze ngenkathi uthola umjovo we-cyclosporine ukuze welashwe ngokushesha uma une-reaction engathí sina yokugula.

Umjovo we-cyclosporine kwesinye isikhathi uyasetshenziswa ukwelapha isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukwehla kwesisindo, nomkhuhlane) nokuvikela ukwenqatshwa kweziguli ezithole ukufakwa kwamanyikwe noma i-cornea. Khuluma nodokotela wakho ngezingozi zokuthola le mithi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-cyclosporine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-cyclosporine (Gengraf, Neoral, Sandimmune), noma imiphi eminye imithi, noma iCremophor EL.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo, noma ohlela ukuzithatha.Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: i-acyclovir (iZovirax); i-allopurinol (iZyloprim); i-amiodarone (iCordarone); i-amphotericin B (i-Amphotec, i-Fungizone); i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril (i-Prinivil, i-Zestril), i-moexipril (i-Univasc), i-perindopril) ), i-ramipril (i-Altace), ne-trandolapril (i-Mavik); ama-angiotensin II receptor antagonists afana ne-candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), ne-valsartan (Diovan); imishanguzo ethile yokulwa nobuthi efana ne-fluconazole (i-Diflucan), i-itraconazole (i-Sporanox), ne-ketoconazole (i-Nizoral); i-azithromycin (iZithromax); i-bromocriptine (Parlodel); ama-calcium channel blocker afana ne-diltiazem (Cardizem), nicardipine (Cardene), nifedipine (Adalat, Procardia), ne-verapamil (Calan); carbamazepine (Carbitrol, Epitol, Tegretol); imithi yokwehlisa i-cholesterol (ama-statins) njenge-atorvastatin (Lipitor), i-fluvastatin (i-Lescol), i-lovastatin (i-Mevacor), i-pravastatin (i-Pravachol), ne-simvastatin (i-Zocor); i-cimetidine (Tagamet); i-ciprofloxacin (i-Cipro); i-clarithromycin (i-Biaxin); colchicine; inhlanganisela ye-dalfopristin ne-quinupristin (Synercid); i-danazol; i-digoxin (i-Lanoxicaps, i-Lanoxin); ama-diuretics athile ('amaphilisi amanzi') afaka i-amiloride (eHydro-ride), i-spironolactone (i-Aldactone), ne-triamterene (iDyazide, iDyrenium, eMaxzide); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-fenofibrate (i-Antara, iLipophen, iTricor); i-gentamicin; I-HIV protease inhibitors efana ne-indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, eKaletra), ne-saquinavir (Fortovase); imatinib (Gleevec); i-metoclopramide (Reglan); i-methylprednisolone (iMedrol); nafcillin; imishanguzo yokulwa nokuvuvukala efana ne-diclofenac (Cataflam, Voltaren), naproxen (Aleve, Naprosyn), ne-sulindac (Clinoril); i-octreotide (iSandostatin); izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amachashazi, okufakelwa kanye nemijovo); i-orlistat (i-alli, i-Xenical); izithako ze-potassium; i-prednisolone (i-Pediapred); i-phenobarbital; i-phenytoin (iDilantin); i-ranitidine (iZantac); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane); i-sulfinpyrazone (i-Anturane); i-terbinafine (iLamisil); i-ticlopidine (iTiclid); i-tobramycin (Tobi); i-trimethoprim ene-sulfamethoxazole (Bactrim, Septra); kanye ne-vancomycin (Vancocin). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha, ikakhulukazi i-wort yaseSt.
• Tshela udokotela wakho uma welashwa nge-phototherapy (ukwelashwa kwe-psoriasis okubandakanya ukuveza isikhumba ekukhanyeni kwe-ultraviolet) futhi uma ngabe uke waba namazinga aphansi we-cholesterol noma i-magnesium egazini lakho noma umfutho wegazi ophakeme.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthola umjovo we-cyclosporine, shayela udokotela wakho. Umjovo we-cyclosporine ungakhuphula ubungozi bokuthi ingane yakho izalwe kusenesikhathi.
• tshela udokotela wakho uma uncelisa noma uhlela ukuncelisa.
• ungabi nayo imigomo ngaphandle kokukhuluma nodokotela wakho.
• kufanele wazi ukuthi i-cyclosporine ingadala ukuthi izicubu ezengeziwe zikhule ezinsinini zakho. Qiniseka ukuthi uxubha amazinyo akho ngokucophelela futhi ubone udokotela wamazinyo njalo ngesikhathi sokwelashwa kwakho ukunciphisa ingozi yokuthi uzoba nalo mphumela ohlangothini.

Gwema ukuphuza ijusi lamagilebhisi noma udle izithelo zomvini ngenkathi uthola umjovo we-cyclosporine.

Udokotela wakho angakutshela ukuthi ulinganisele inani le-potassium ekudleni kwakho. Landela le miyalo ngokucophelela. Khuluma nodokotela wakho ngenani lokudla okune-potassium eningi njengobhanana, umlimi unquma, omisiwe nejusi le-orange ongahle ube nalo ekudleni kwakho. Izinhlobo eziningi zikasawoti zine-potassium, ngakho-ke khuluma nodokotela wakho ngokuzisebenzisa ngesikhathi sokwelashwa kwakho.

Umjovo we-cyclosporine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isifo sohudo
• isicanucanu
• ukuhlanza
• ukukhula kwezinwele ukukhula ebusweni, ezingalweni nasemhlane
• ukuvuvukala kwezicubu zezinsini, noma ukukhula kwezicubu ezengeziwe ezinsinini
• induna
• ukuzamazama okungalawuleki kwengxenye yomzimba wakho
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukudonsa ezandleni, izingalo, izinyawo, noma imilenze
• amajaqamba
• ukukhuliswa kwamabele emadodeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuqhuma ebusweni noma esifubeni
• ukuphelelwa umoya
• isifuba
• ukushaya kwenhliziyo okusheshayo
• ukuqubuka
• isifuba
• ukulunywa
• ubunzima bokugwinya
• ukulahlekelwa ukwazi
• isithuthwane
• ushintsho esimweni sengqondo noma ekuziphatheni
• ubunzima bokuhamba
• izinkinga zokubona noma ukucishwa ngokuzumayo
• ukuvuvukala kwezandla, izingalo, izinyawo, amaqakala, noma imilenze engezansi

Umjovo we-cyclosporine ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-cyclosporine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• USandimmune^® Ukujova