I-Didanosine

-Delile

• Ngaphambi kokuthatha i-didanosine,
• I-Didanosine ingadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Didanosine ingadala i-pancreatitis ebucayi noma esongela impilo (ukuvuvukala kwamanyikwe). Tshela udokotela wakho uma uphuza noma uphuze kakhulu iziphuzo ezidakayo futhi uma uke waba noma uke waba ne-pancreatitis, noma amanyikwe noma isifo sezinso. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu besisu noma ukuvuvukala, isicanucanu, ukuhlanza, noma umkhuhlane.

I-Didanosine ingadala umonakalo osongela impilo esibindini kanye nesimo esisongela impilo esibizwa nge-lactic acidosis (i-lactic acid egazini). Ingcuphe yokuthi uzoba ne-lactic acidosis ingahle ibe phezulu uma ungowesifazane, uma ukhuluphele ngokweqile, noma ngabe welashwe ngemithi ye-HIV isikhathi eside. Tshela udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso. Tshela udokotela wakho uma uthatha i-stavudine (Zerit). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-didanosine uma uthatha lo muthi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo: ukuphefumula; ukuphefumula okusheshayo; izinguquko ekushayeni kwenhliziyo; isicanucanu; ukuhlanza; ukulahlekelwa ukudla; ukuncipha komzimba; isifo sohudo; ubuhlungu engxenyeni engenhla yangakwesokudla yesisu sakho; ukopha okungavamile noma ukulimaza; ukuphuzi kwesikhumba noma kwamehlo; umchamo onombala omnyama; ukunyakaza kwamathumbu okukhanyayo; ukukhathala ngokweqile; izandla nezinyawo ezinemibala ebandayo noma eluhlaza okwesibhakabhaka; noma ubuhlungu bemisipha.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-didanosine.

Khuluma nodokotela wakho ngezingozi zokuthatha i-didanosine.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-didanosine futhi isikhathi ngasinye ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

IDidanosine isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV). I-Didanosine isekilasini lemithi ebizwa nge-nucleoside reverse transcriptase inhibitors (NRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Yize i-didanosine ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko empilweni kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

IDidanosine iza njengama-capsule akhishwe isikhathi eside (asebenza isikhathi eside) futhi njengesixazululo somlomo (uketshezi) ukuthatha ngomlomo. Isixazululo somlomo ngokuvamile sithathwa kanye noma kabili ngosuku ngemizuzu engama-30 ngaphambi noma amahora amabili ngemuva kokudla. Ama-capsule akhululwa enwetshiwe ngokuvamile athathwa kanye ngosuku esiswini esingenalutho. Thatha i-didanosine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-didanosine njengoba nje iyalelwe. Ungayithathi kancane, noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma usebenzisa amaphilisi akhululiwe, uwagwinye wonke; musa ukuhlukanisa, ukuhlafuna, ukuchoboza, ukuphula, noma ukukuqothula. Tshela udokotela wakho uma ungakwazi ukugwinya amaphilisi akhishwe wonke.

Uma uthatha isisombululo somlomo, kufanele usinyakazise kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo. Sebenzisa isipuni noma inkomishi yokulinganisa umthamo ukukala inani elifanele liketshezi kumthamo ngamunye, hhayi isipuni sasendlini esijwayelekile.

IDidanosine ilawula ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka uthathe i-didanosine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-didanosine ngaphandle kokukhuluma nodokotela wakho. Uma uphuthelwa amanani noma uyeka ukuthatha i-didanosine, isimo sakho singaba nzima ukwelapha.

I-Didanosine kwesinye isikhathi isetshenziswa neminye imithi yokusiza ukuvimbela ukutheleleka kubasebenzi bezokunakekelwa kwezempilo noma abanye abantu abachayeke ngengozi ku-HIV. Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-didanosine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-didanosine, noma imuphi omunye umuthi, noma iziphi izithako ezikuma-didanosine capsules noma isixazululo somlomo. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-allopurinol (Aloprim, Lopurin, Zyloprim), noma i-ribavirin (iCopegus, iRebetol, iVirazole). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-didanosine uma uthatha eyodwa noma yomibili yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yimiphi imithi ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nakokulandelayo: ama-antiacid aqukethe i-aluminium noma i-magnesium (Maalox, Mylanta, abanye): ama-antifungal anjenge-itraconazole (Sporanox) ne-ketoconazole; atazanvir (Reyataz); ama-antibiotic afana ne-ciprofloxacin (Cipro), gatifloxacin (Tequin), moxifloxacin (Avelox), ofloxacin (Floxin), pentamidine (Nebupent, Pentam), sulfamethoxazole ne-trimethoprim (Bactrim, Septra), ne-tetracycline (Sumycin); i-cabazitaxel (i-Jevtana); i-dapsone (i-Aczone); i-delavirdine (i-Rescriptor); i-docetaxel (Taxotere); i-ganciclovir (i-cytovene); i-hydroxyurea (iDroxia, i-Hydrea); indinavir (Crixivan); i-methadone (i-Dolophine, i-Methadose); i-nelfinavir (i-Viracept); i-paclitaxel (i-Abraxane, i-Taxol); ipentamidine (Nebupent, Pentam); i-ranitidine (iZantac); i-ritonavir (i-Norvir); i-sulfamethoxazole ne-trimethoprim (iBactrim, Septra). i-tenofovir (Viread); i-tipranavir (i-Aptivus); i-valganciclovir (iValcyte); noma i-vincristine (Marqibo). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho, ashintshe lapho uthatha imishanguzo yakho, noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-didanosine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma ngabe uke waba ne-peripheral neuropathy (ukuba ndikindiki, ukushosholoza, ukushisa, noma ukuzwa ubuhlungu ezandleni zakho noma ezinyaweni, noma wehlise ikhono lokuzwa ukushisa noma ukuthinta ezandleni zakho noma ezinyaweni) noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-didanosine, shayela udokotela wakho.Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthatha i-didanosine.
• kufanele wazi ukuthi i-didanosine ingadala imiphumela emibi okufanele ilashwe ngokushesha ngaphambi kokuba ibe yimbi. Izingane ezithatha i-didanosine kungenzeka zingakwazi ukukutshela ngemiphumela emibi eziyizwayo. Uma unikeza ingane i-didanosine, buza udokotela wengane ukuthi ungabona kanjani ukuthi ingane inale miphumela emibi kakhulu.
• kufanele wazi ukuthi ungahle ulahlekelwe ngamafutha omzimba ebusweni bakho, emilenzeni, ezingalweni nasezinqeni. Khuluma nodokotela wakho uma ubona lolu shintsho.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi ngemuva kokuqala ukwelashwa nge-didanosine, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Didanosine ingadala imiphumela emibi. Tshela udokotela wakho uma lesi sibonakaliso sinzima noma singapheli:

• ikhanda

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuba ndikindiki, ukuhayiza, ukushisa, noma ubuhlungu ezandleni noma ezinyaweni
• umbono uyashintsha
• ubunzima bokubona imibala ngokucacile

I-Didanosine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina amaphilisi e-didanosine esitsheni afike ngaso, avalwe ngci, futhi lapho izingane zingafinyeleleki khona. Zigcine ekamelweni lokushisa kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Gcina isisombululo somlomo se-didanosine esiqandisini, uvale uvalwe, bese ulahla noma imuphi umuthi ongasetshenziswanga ngemuva kwezinsuku ezingama-30.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isifo sohudo
• ukuba ndikindiki, ukuhayiza, ukushisa, noma ubuhlungu ezandleni noma ezinyaweni
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• ukuvuvukala kwesisu
• ubuhlungu bemisipha noma bamalunga
• ukukhathala ngokweqile
• ubuthakathaka
• isiyezi
• ubumhlophe
• ukushaya kwenhliziyo okusheshayo, okuhamba kancane noma okungajwayelekile
• ukuphefumula okujulile noma okusheshayo
• ukuphelelwa umoya
• umchamo omnyama ophuzi noma onsundu
• ukopha okungajwayelekile noma ukulinyazwa
• ukuhlanza into enegazi noma ebukeka njengezizathu zekhofi
• indle emnyama
• ukuphuzi kwesikhumba noma kwamehlo
• ngizwe kubanda
• imfiva
• izimpawu ezinjengomkhuhlane

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina ukutholakala kwe-didanosine kusesandleni. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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• I-Videx^®

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