Umjovo wePentostatin

-Delile

• Ngaphambi kokuthola i-pentostatin,
• I-Pentostatin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo wePentostatin kufanele unikezwe ngaphansi kweso lodokotela onolwazi lokunikeza imishanguzo yamakhemikhali yomdlavuza.

I-Pentostatin ingadala imiphumela emibi kakhulu, kufaka phakathi ukulimala kwesistimu yezinzwa. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuquleka; ukudideka; ukozela; ukulahlekelwa ukwazi isikhathi esithile; ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuhayiza ezandleni noma ezinyaweni; noma ubuthakathaka ezingalweni noma emlenzeni noma ekulahlekelweni ikhono lokuhambisa izingalo noma imilenze.

Esifundweni somtholampilo, abantu abane-lymphocytic leukemia engapheli abasebenzisa umjovo we-pentostatin kanye ne-fludarabine (Fludara) babesengozini enkulu yokuthola umonakalo omkhulu wamaphaphu. Kwezinye izimo, lokhu kulimala kwamaphaphu kwabangela ukufa. Ngakho-ke, udokotela wakho ngeke anikeze umjovo we-pentostatin okufanele unikezwe kanye ne-fludarabine (Fludara).

I-Pentostatin isetshenziselwa ukwelapha i-leukemia yamangqamuzana anoboya (umdlavuza wohlobo oluthile lweseli emhlophe yegazi).I-Pentostatin uhlobo lwama-antibiotic olusetshenziswa kuphela ekwelashweni ngamakhemikhali omdlavuza. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

I-Pentostatin iza njengempuphu ezoxutshwa noketshezi futhi ifakwe ngomjovo (emthanjeni) ngaphezulu kwemizuzu engu-5 noma ifakwe ngaphakathi ngemizuzu engaphezu kwengama-20 kuye kwengama-30 ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Kuvame ukujova kanye njalo ngesonto. Ubude bokwelashwa buxhomeke ekutheni umzimba wakho uphendula kanjani ekwelashweni nge-pentostatin.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma ushintshe umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho ngomjovo we-pentostatin.

I-Pentostatin kwesinye isikhathi isetshenziselwa ukwelapha i-lymphocytic leukemia (CLL; uhlobo lomdlavuza wamangqamuzana amhlophe egazi) kanye ne-T-cell lymphoma (uhlobo lomdlavuza oluqala ohlotsheni lwamaseli amhlophe egazi ngokuvamile alwa nokutheleleka futhi okuthinta isikhumba). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-pentostatin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-pentostatin, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-pentostatin. Buza usokhemisi wakho noma uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SESEXWAYISO noma i-allopurinol (iZyloprim). Udokotela wakho angadinga ukukuqapha ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma ngabe usanda kuthola noma usanda kuthola isifo noma uma uke waba nesifo sezinso noma sesibindi.
• ell udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma ukuncelisa. Akufanele ukhulelwe ngenkathi uthola i-pentostatin. Uma ukhulelwa ngenkathi uthola i-pentostatin, shayela udokotela wakho. IPentostatin ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Pentostatin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukuqunjelwa
• izilonda emlonyeni nasemphinjeni
• ukuqumba noma inani elikhulu legesi emathunjini noma emathunjini
• ukulahleka kwezinwele
• ubuhlungu bemisipha, emuva, noma obuhlangene
• ikhanda
• ukujuluka
• ubunzima bokulala noma ukulala
• isikhumba esomile
• ukulunywa
• ukuphelelwa amandla noma amandla

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuphefumula kanzima
• ukuphelelwa umoya
• isifuba
• ukukhwehlela
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza kwegazi; okokuhlanza okubukeka njengezizathu zekhofi
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• ubuhlungu besifuba
• isiyezi
• ukuquleka
• ukuphuzi kwesikhumba noma kwamehlo
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• umchamo onombala omnyama
• ukuncipha kokuchama
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuqubuka
• umbono uyashintsha
• izinguquko ekuzweni

I-Pentostatin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kwi-pentostatin.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nepentostatin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Nipent^®

• 2’-Deoxycoformycin
• Co-vidarabine