I-Interferon Beta-1a Injection Yangaphakathi

-Delile

• Umjovo we-Interferon beta-1a we-intramuscular isetshenziselwa ukwelapha abantu abadala abanezinhlobo ezahlukahlukene ze-multiple sclerosis (MS; isifo lapho izinzwa zingasebenzi kahle futhi abantu bangathola ubuthakathaka, ukuba ndikindiki, ukulahleka kokuhlangana kwemisipha, nezinkinga ngombono, ukukhuluma, nokulawula isinye) kufaka phakathi:
• Ngaphambi kokusebenzisa i-interferon beta-1a,
• I-Interferon beta-1a ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

Umjovo we-Interferon beta-1a we-intramuscular isetshenziselwa ukwelapha abantu abadala abanezinhlobo ezahlukahlukene ze-multiple sclerosis (MS; isifo lapho izinzwa zingasebenzi kahle futhi abantu bangathola ubuthakathaka, ukuba ndikindiki, ukulahleka kokuhlangana kwemisipha, nezinkinga ngombono, ukukhuluma, nokulawula isinye) kufaka phakathi:

• i-syndrome ehlukanisiwe nomtholampilo (i-CIS; iziqephu zezimpawu zemizwa ezihlala okungenani amahora angama-24),
• amafomu wokubuyisela emuva (inkambo yesifo lapho izimpawu zivela khona ngezikhathi ezithile), noma
• amafomu wesibili aqhubekayo (inkambo yesifo lapho ukubuyela emuva kwenzeka kaningi).

I-Interferon beta-1a isekilasini lemithi ebizwa ngama-immunomodulators. Isebenza ngokunciphisa ukuvuvukala nokuvimbela ukulimala kwezinzwa okungadala izimpawu ze-multiple sclerosis.

Umjovo we-Interferon beta-1a we-intramuscular uza njenge-powder ezitsheni ezizoxutshwa nesisombululo somjovo. Umjovo we-Interferon beta-1a we-intramuscular uza futhi njengesixazululo (uketshezi) emijovweni yokujova ekhethiwe nasendaweni ebekiwe yokufaka okuzenzakalelayo. Lo muthi ufakwa emisipheni, imvamisa kanye ngesonto, ngosuku olufanayo ngesonto. Jova i-interferon beta-1a emithanjeni ngesikhathi esifanayo sosuku ngezinsuku zakho zomjovo. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-interferon beta-1a njengoba iqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

I-Interferon beta-1a ilawula izimpawu ze-MS kepha ayiyelaphi. Qhubeka nokusebenzisa i-interferon beta-1a noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa i-interferon beta-1a ngaphandle kokukhuluma nodokotela wakho.

Uzothola umthamo wakho wokuqala we-interferon beta-1a intramuscular ehhovisi likadokotela wakho. Ngemuva kwalokho, ungafaka umjovo we-interferon beta-1a ngaphakathi kwemisipha noma ube nomngane noma isihlobo esenza imijovo. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani. Ngaphambi kokusebenzisa i-interferon beta-1a intramuscular okokuqala, wena noma umuntu ozonikeza imijovo kufanele futhi ufunde imininingwane yomenzi wesiguli esiza nayo. Landela izinkomba ngokucophelela.

Qiniseka ukuthi uyazi ukuthi uluhlobo luni lwesitsha i-interferon beta 1b yakho engenayo nokuthi iziphi ezinye izinto, njengezinaliti noma imijovo, oyodinga ukujova umuthi wakho. Uma i-interferon beta 1b intramuscular iza ngezimbiza, kuzodingeka usebenzise isirinji nenaliti ukujova umthamo wakho.

Sebenzisa ngaso sonke isikhathi isitsha esisha, esingavulwa, isipetu esenziwe ngaphambili nenaliti, noma ipeni lomjovo othomathikhi ozenzele lona ngomjovo ngamunye. Ungalokothi uphinde usebenzise izitsha, amasirinji, izinaliti, noma izibaya zomjovo ezizenzakalelayo. Lahla imijovo esetshenzisiwe, izinaliti nezibaya zomjovo esitsheni esingamelana nokubhoboza, okugcinwa kude nezingane. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Njalo bheka umuthi esitsheni sakho, isirinji ekhethiwe, noma ipeni lomjovo othomathikhi ngaphambi kokulisebenzisa. Uma usebenzisa i-vial, ikhambi eliku-vial kufanele licace kuphuzi kancane ngemuva kokuxubeka. Uma usebenzisa isirinji ekhethiwe noma ipeni lomjovo othomathikhi, isixazululo kufanele sicace futhi singabi nombala. Uma isixazululo sinamafu, sikhanya umbala, noma siqukethe izinhlayiya noma uma usuku lokuphelelwa yisikhathi olumakwe esitsheni, isirinji ekhethiwe, noma ipeni lomjovo othomathikhi seludlulile, ungayisebenzisi leyo vial, isiponji esivele ifakiwe, noma ipeni lomjovo othomathikhi.

Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi yikuphi emzimbeni wakho lapho kufanele ujove khona i-interferon beta-1a intramuscular. Uma usebenzisa isipetu noma isirinji efakiwe, ungafaka i-interferon beta-1a intramuscular ezingalweni noma emathangeni akho aphezulu. Uma usebenzisa ipeni yokufaka i-autoinjection oyithandayo, ungajova i-interferon beta-1a intramuscular engaphandle lamathanga akho aphezulu. Sebenzisa indawo ehlukile ngomjovo ngamunye. Ungasebenzisi indawo efanayo izikhathi ezimbili zilandelana. Musa ukujova endaweni lapho isikhumba sinobuhlungu, sibomvu, silimele, sinezibazi, sinegciwane, sicasukile, noma singavamile nganoma iyiphi indlela.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (umhlahlandlela wemithi) lapho uqala ukwelashwa nge-interferon beta-1a futhi isikhathi ngasinye ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola i-interferon beta-1a Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-interferon beta-1a,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-interferon beta-1a, noma yimiphi eminye imithi ye-interferon (i-Betaseron, i-Extavia, i-Plegridy, i-Rebif), noma imiphi eminye imishanguzo, i-albin yabantu, iraba yemvelo, i-latex, noma ezinye izithako ku-interferon beta- 1a umjovo we-intramuscular. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uphuza noma wake waphuza utshwala obuningi futhi uma uke waba nesifo esizimele ngaphandle kwe-MS (isifo lapho umzimba uhlasela amangqamuzana awo; buza udokotela wakho uma ungaqiniseki lolu hlobo lwesifo); izinkinga zegazi ezifana ne-anemia (amangqamuzana abomvu egazi angalethi umoya-mpilo owenele kuzo zonke izingxenye zomzimba), amaseli egazi amhlophe aphansi, noma ukulimaza noma ukopha okulula; ukugula ngengqondo njengokucindezeleka, ikakhulukazi uma uke wacabanga ukuzibulala noma uzame ukwenza kanjalo; ezinye izifo zemizwa noma ukugula kwengqondo; ukuquleka; noma isifo senhliziyo, isibindi noma i-thyroid.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-interferon beta-1a, shayela udokotela wakho ngokushesha.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-interferon beta-1a.
• buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi usebenzisa i-interferon beta-1a. Utshwala bungandisa ingozi yokuthi uzoba nemiphumela emibi kakhulu kusuka ku-interferon beta-1a.
• kufanele wazi ukuthi ungaba nezimpawu ezifana nomkhuhlane njengekhanda, umkhuhlane, ukugodola, ukujuluka, izinhlungu zemisipha, isicanucanu, ukuhlanza nokukhathala okuhlala usuku lonke ngemuva komjovo wakho. Udokotela wakho angakutshela ukuthi ujove umuthi wakho ngesikhathi sokulala bese uthatha imishanguzo yokugula kanye nemfiva ukusiza ngalezi zimpawu. Lezi zimpawu zivame ukwehla noma zihambe ngokuhamba kwesikhathi. Khuluma nodokotela wakho uma lezi zimpawu kunzima ukuphatha noma ziba nzima.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Jova umthamo ophuthelwe ngokushesha nje lapho uwukhumbula. Musa ukujova i-interferon beta-1a izinsuku ezimbili zilandelana. Musa ukujova umthamo ophindwe kabili ukwenzela umthamo ongabanjwanga. Buyela esimisweni sakho sokulinganisa okujwayelekile ngesonto elilandelayo. Shayela udokotela wakho uma uphuthelwa umthamo futhi unemibuzo mayelana nokuthi wenzeni.

I-Interferon beta-1a ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• imisipha eqinile
• isiyezi
• ukuba ndikindiki, ukushiswa, ukuhayiza, noma ubuhlungu ezandleni noma ezinyaweni
• ubuhlungu obuhlangene
• izinkinga zamehlo
• ikhala eligijimayo
• ubuhlungu bamazinyo
• ukulahleka kwezinwele
• ukulimaza, ubuhlungu, ubomvu, ukuvuvukala, ukopha, noma ukucasuka endaweni yomjovo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukucindezeleka okusha noma okuya kuba kubi
• ukucabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo
• ukuzwa ngokomzwelo kakhulu
• ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho)
• isithuthwane
• ukuzuza kwesisindo esingaqondakali noma ukulahleka
• ukuzwa kubanda noma kushisa ngaso sonke isikhathi
• inkinga yokuphefumula lapho ulele embhedeni
• isidingo esengeziwe sokuchama ebusuku
• ukuchama kabuhlungu noma okunzima
• ukuncipha kwekhono lokuzivocavoca umzimba
• ubuhlungu besifuba noma ukuqina
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• isikhumba esiphaphathekile
• ukukhathala ngokweqile
• ukungabi namandla
• ukulahlekelwa isifiso sokudla
• ukopha okungajwayelekile noma ukulinyazwa
• ubuhlungu noma ukuvuvukala engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• umchamo onsundu onsundu
• ukunyakaza kwamathumbu okukhanyayo
• umphimbo obuhlungu, ukukhwehlela, noma ezinye izimpawu zokutheleleka
• isifuba
• ukuqubuka
• ukulunywa
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izingalo, izinyawo, amaqakala noma imilenze engezansi
• ukuphefumula kanzima noma ukugwinya
• ukushaqeka
• ukuqhuma
• indle ebomvu noma enegazi noma isifo sohudo
• ubuhlungu besisu
• inkulumo ehamba kancane noma enzima
• Amachashazi ansomi noma amachashazi wokukhomba (ukuqubuka) esikhunjeni
• kunciphise ukuchama noma igazi emchameni

I-Interferon beta-1a ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amasirinji we-interferon beta-1a agcwaliswe ngaphakathi emithanjeni, izitsha, nezibaya zomjovo ezizenzakalelayo esiqandisini. Ungafaki i-beta-1a ye-interferon, futhi ungachazi umuthi emazingeni okushisa aphezulu. Uma isiqandisi singatholakali, ungagcina izingqayi ze-interferon beta-1a efakwa ngaphakathi kwemisipha ekamelweni lokushisa, kude nokushisa nokukhanya, kuze kube yizinsuku ezingama-30. Ngemuva kokuxuba i-interferon beta-1a powder namanzi oyinyumba, yigcine esiqandisini bese uyisebenzisa kungakapheli amahora ayisithupha. Uma isiqandisi singatholakali, ungagcina imijovo ethandwayo nezibaya zomjovo ekamelweni lokushisa, kude nokushisa nokukhanya, kuze kube yizinsuku eziyi-7.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-interferon beta-1a.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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