Stavudine

-Delile

• Ngaphambi kokuthatha i-stavudine,
• IStavudine ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma ezinye zalezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

IStavudine ingadala i-lactic acidosis ebucayi noma esongela impilo (ukwakhiwa kwe-asidi egazini) okungenzeka ukuthi izodinga ukwelashwa esibhedlela. Ingcuphe yokuthi uzoba ne-lactic acidosis iphezulu uma ungowesifazane, uma ukhuluphele ngokweqile, futhi uma welashwe ngemishanguzo yegciwane lengculazi (i-HIV) isikhathi eside. Ingozi nayo ingaphakama uma ukhulelwe futhi uthatha i-stavudine kanye ne-didanosine (Videx). Tshela udokotela wakho uma ngabe unesifo sesibindi noma owake waba naso, kufaka phakathi ukutheleleka kwegciwane le-hepatitis C. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isicanucanu; ukuhlanza; ukulahlekelwa ukudla; ukukhathala ngokweqile; ubuthakathaka; isiyezi; ikhanda elikhanyayo; ukushaya kwenhliziyo okusheshayo noma okungajwayelekile; ukuphefumula kanzima; umchamo omnyama ophuzi noma onsundu; ukopha okungavamile noma ukulimaza; izimpawu ezinjengomkhuhlane; ukunyakaza kwamathumbu okukhanyayo; ukuphuzi kwesikhumba noma kwamehlo; ubuhlungu engxenyeni engenhla yangakwesokudla yesisu sakho; ukuzwa ukubanda, ikakhulukazi ezandleni noma emilenzeni; noma ubuhlungu bemisipha obuhlukile kunoma yibuphi ubuhlungu bemisipha ovame ukubuzwa.

I-Stavudine ingadala i-pancreatitis ebucayi noma esongela impilo (ukuvuvukala kwamanyikwe). Tshela udokotela wakho uma uphuza noma wake waphuza kakhulu iziphuzo ezidakayo nokuthi ngabe uke waba ne-pancreatitis noma wake waba nayo yini. Ungaphuzi utshwala ngenkathi uthatha i-stavudine. Tshela nodokotela wakho uma uthatha i-didanosine (Videx). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu besisu noma ukuvuvukala, isicanucanu, ukuhlanza noma umkhuhlane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-stavudine.

Khuluma nodokotela wakho ngezingozi zokuthatha i-stavudine.

IStavudine isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV). UStavudine usesigabeni semithi ebizwa nge-nucleoside reverse transcriptase inhibitors (NRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Yize i-stavudine ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

IStavudine iza njengephilisi futhi njengesisombululo somlomo (uketshezi) okufanele sithathwe ngomlomo. Imvamisa iphuzwa kabili ngosuku (njalo emahoreni ayi-12), nokudla noma ngaphandle kokudla namanzi amaningi. Ukukusiza ukuthi ukhumbule ukuthatha i-stavudine, yithathe ngezikhathi ezifanayo usuku ngalunye. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-stavudine njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma unikeza isisombululo somlomo enganeni, yinyakazise kahle ibhodlela ngaphambi kokusetshenziswa ngakunye ukuxuba umuthi ngokulinganayo. Sebenzisa inkomishi yokulinganisa enikeziwe ukukala umthamo wengane.

IStavudine ilawula ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka nokuthatha i-stavudine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-stavudine ngaphandle kokukhuluma nodokotela wakho. Lapho ukunikezwa kwakho kwe-stavudine kuqala ukwehla, thola okuningi kudokotela wakho noma ekhemisi. Uma uphuthelwa imithamo noma ngokungazelelwe uyeke ukuthatha i-stavudine, isimo sakho singaba nzima ukwelashwa.

IStavudine kwesinye isikhathi isetshenziswa ngokuhlangana neminye imishanguzo yokuvikela ukutheleleka nge-HIV kubasebenzi bezokunakekelwa kwezempilo noma abanye abantu abachayeke ngengozi ku-HIV. Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-stavudine,

• Tshela udokotela kanye nosokhemisi wakho uma ungenwe i-stavudine, noma imiphi imithi, noma iziphi izithako ezikuma-capsules e-stavudine noma kwisisombululo somlomo. Buza usokhemisi wakho ukuthola uhlu lwezithako noma hlola umhlahlandlela wemithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo nemikhiqizo yamakhambi oyithathayo. Qiniseka ukubalula labo ababalwe esigabeni ESIBALULEKILE SEXWAYISO kanye ne-doxorubicin, i-hydroxyurea (i-Droxia, i-Siklos), i-ribavirin (i-Rebetol, i-Ribasphere), noma i-zidovudine (i-Retrovir, e-Combivir, e -Trizivir). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uthola ukwelashwa nge-dialysis noma uma uke waba nesifo sezinso, isifo sikashukela, noma i-peripheral neuropathy (uhlobo lokulimala kwemizwa okubangela ukuhayiza, ukuba ndikindiki, nobuhlungu ezandleni nasezinyaweni).
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-stavudine, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uphuza i-stavudine.
• kufanele wazi ukuthi i-stavudine ingadala imiphumela emibi okufanele ilashwe ngokushesha ngaphambi kokuba ibe yimbi. Izingane ezithatha i-stavudine kungenzeka zingakwazi ukukutshela ngemiphumela emibi eziyizwayo. Uma unikeza ingane i-stavudine, buza udokotela wengane ukuthi ungabona kanjani ukuthi ingane inale miphumela emibi kakhulu.
• kufanele wazi ukuthi ungalahlekelwa ngamafutha omzimba ebusweni bakho, emilenzeni nasezingalweni. Khuluma nodokotela wakho uma ubona lolu shintsho.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi ngemuva kokuqala ukwelashwa nge-stavudine, qiniseka ukuthi utshela udokotela wakho.
• uma unesifo sikashukela, kufanele wazi ukuthi kukhona ama-50 mg we-sucrose kutipuni ngalinye (5 ml) lesisombululo somlomo se-stavudine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IStavudine ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:

• ikhanda
• isifo sohudo
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma ezinye zalezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuba ndikindiki, ukuhayiza, ukushisa noma ubuhlungu ezandleni noma ezinyaweni
• ubunzima bokuhambisa izandla nezinyawo zakho

IStavudine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amaphilisi ekamelweni lokushisa kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Gcina isisombululo somlomo esiqandisini bese ulahla ingxenye engasetshenziswanga ngemuva kwezinsuku ezingama-30.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuba ndikindiki, ukudikiza, ubuthakathaka, noma ubuhlungu ezandleni noma ezinyaweni
• ukuhlanza
• ubuhlungu obungavamile noma obungalindelekile besisu
• ubuthakathaka noma ukukhathala
• ukuphelelwa umoya

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina istavudine ezandleni zakho. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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