Inaliti ye-Ifosfamide

-Delile

• Ngaphambi kokuthola ifosfamide,
• ifosfamide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-ifosfamide ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho wethambo. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okuyingozi noma okusongela impilo noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, amakhaza, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; ezinegazi noma ezimnyama, izitulo zokulinda; ukuhlanza kwegazi; noma ukugabha igazi noma okokusundu okufana nezindawo zekhofi.

I-Ifosfamide ingadala umonakalo omkhulu noma osongela impilo ohlelweni lwezinzwa. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukudideka; ukozela; ukungaboni kahle; ukubona izinto noma ukuzwa amazwi angekho (ukusangana); noma ubuhlungu, ukuvutha, ukuba ndikindiki, ukuhayiza ezandleni noma ezinyaweni; ukuquleka; noma ikhoma (ukulahlekelwa ukwazi isikhathi esithile).

I-ifosfamide ingadala izinkinga zezinso ezinzima noma ezisongela ukuphila. Izinkinga zezinso zingenzeka ngesikhathi sokwelapha noma izinyanga noma iminyaka ngemuva kokuyeka ukwelashwa. Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuncipha kokuchama; ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukukhathala okungajwayelekile noma ubuthakathaka.

I-Ifosfamide ingadala imiphumela emibi kakhulu yomchamo. Tshela udokotela wakho uma unenkinga yokuchama. Udokotela wakho angakutshela ukuthi ungayitholi ifosfamide noma ulinde ukuqala ukwelashwa uze ukwazi ukuchama njalo. Phinda utshele udokotela wakho uma unesifo somgudu womchamo noma uma uke wanayo noma wake waba nokwelashwa ngemisebe (x-ray) esinyeni. Tshela udokotela kanye nosokhemisi wakho uma uthatha noma wake wathola i-busulfan (Busulfex). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: igazi emchameni noma ukuchama kaningi, okuphuthumayo noma okubuhlungu. Udokotela wakho uzokunika omunye umuthi wokusiza ukuvimbela imiphumela emibi kakhulu yomchamo ngenkathi welashwa nge-ifosfamide. Kufanele futhi uphuze uketshezi oluningi bese uchama njalo ngesikhathi sokwelashwa kwakho ukusiza ukunciphisa imiphumela emibi yomchamo.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda ukuhlolwa kwelabhorethri njalo ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-ifsofamide kanye nokwelashwa ngemiphumela engemihle ngaphambi kokuba ibe nzima.

I-ifosfamide isetshenziswa ngokuhlangana neminye imithi yokwelapha umdlavuza wamasende ongakathuthuki noma osuke waba muncu ngemuva kokwelashwa ngeminye imishanguzo noma ngemisebe yelanga. I-ifosfamide isekilasini lemithi ebizwa ngama-alkylating agents. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

I-ifosfamide iza njengempuphu ezohlanganiswa noketshezi oluzofakwa okungenani imizuzu engama-30 ngemithambo (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Ingafakwa kanye ngosuku izinsuku ezi-5 zilandelana. Lokhu kwelashwa kungaphindwa njalo emavikini amathathu. Ubude bokwelashwa buxhomeke ekutheni umzimba wakho uphendula kahle kanjani ekwelashweni nge-ifosfamide.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-ifosfamide.

I-ifosfamide kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza wesinye, umdlavuza wamaphaphu, umdlavuza wama-ovari (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda), umdlavuza womlomo wesibeletho, nezinhlobo ezithile zezicubu ezithambile noma amathambo ama-sarcomas (umdlavuza owakhekayo emisipheni nasemathanjeni). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola ifosfamide,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-ifosfamide, i-cyclophosphamide (i-cytoxan), noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-ifosfamide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini nezithako zokudla okunomsoco owutholayo noma ohlela ukukuthatha. Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SEXWAYISO nokunye okulandelayo: i-aprepitant (Emend); ezinye izinto zokuvikela ezifana ne-fluconazole (i-Diflucan), i-itraconazole (i-Sporanox), ne-ketoconazole (i-Nizoral); imishanguzo ethile yokuquleka efana ne-carbamazepine (Tegretrol), phenobarbital (Luminal), ne-phenytoin (Dilantin); imithi yokungezwani komzimba noma i-hay fever; imithi yesicanucanu; imishanguzo ye-opioid (narcotic) yezinhlungu; i-rifampin (i-Rifadin, i-Rimactane); isidambisi; amaphilisi okulala; noma i-sorafenib (Nexavar). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo ingaxhumana ne-ifosfamide, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyitholayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyitholayo, ikakhulukazi iSt.
• utshele udokotela wakho ukuthi wake wakuthola ukwelashwa ngeminye imithi yokwelapha ngamakhemikhali noma uma wake wathola ukwelashwa ngemisebe ngaphambilini. Phinda utshele udokotela wakho uma uke waba nesifo senhliziyo, sezinso noma sesibindi.
• kufanele wazi ukuthi ifosfamide inganciphisa ukwelashwa kwamanxeba.
• kufanele wazi ukuthi ifosfamide ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane futhi ingamisa ukukhiqizwa kwesidoda emadodeni. I-ifosfamide ingadala ukungabi nenzalo unomphela (ubunzima bokukhulelwa); noma kunjalo, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukuthola lo muthi. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola i-ifosfamide. Sebenzisa indlela ethembekile yokulawula ukubeletha ukuvimbela ukukhulelwa ngenkathi uthola i-ifosfamide nezinyanga eziyisithupha ngemuva kokwelashwa. Uma ungowesilisa, wena nozakwenu kufanele niqhubeke nokulawula inzalo izinyanga eziyisithupha ngemuva kokuyeka ukuthola umjovo we-ifosfamide. Uma ukhulelwa ngenkathi uthola i-ifsofamide, shayela udokotela wakho ngokushesha. Ifosfamide ingalimaza umbungu.

Ungadli inani elikhulu lamagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthola lo muthi.

ifosfamide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• isifo sohudo
• izilonda emlonyeni nasemphinjeni
• ukulahleka kwezinwele
• ukuzwa okujwayelekile kobuhlungu nokukhathala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuvuvukala, ububomvu, nobuhlungu endaweni lapho kwajova khona umuthi
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuphelelwa umoya
• isifuba
• ukushaya kwenhliziyo okungajwayelekile
• ubuhlungu besifuba
• ukushaqeka
• ukuphuzi kwesikhumba noma kwamehlo

I-ifosfamide ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-ifosfamide.

I-Ifosfamide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukungaboni kahle
• ukubona izinto noma ukuzwa amazwi angekho (hallucinating)
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza okunegazi
• okokuhlanza okubukeka njengezizathu zekhofi
• ukuncipha kokuchama
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• izilonda emlonyeni nasemphinjeni
• isithuthwane
• ukudideka
• ikhoma (ukulahlekelwa ukwazi isikhathi esithile)

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela.Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ifex^®

• Isophosphamide