Umjovo wePegaspargase

-Delile

• Ngaphambi kokuthola i-pegaspargase,
• I-Pegaspargase ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Pegaspargase isetshenziswa nezinye izidakamizwa ze-chemotherapy ukwelapha uhlobo oluthile lwe-acute lymphocytic leukemia (BONKE; uhlobo lomdlavuza wamaseli amhlophe egazi). I-Pegaspargase nayo isetshenziswa nezinye izidakamizwa ze-chemotherapy ukwelapha uhlobo oluthile LONKE kubantu abake baba nezinhlobo ezithile zokungezwani komzimba nemithi efana ne-pegaspargase efana ne-asparaginase (i-Elspar). I-Pegaspargase iyi-enzyme ephazamisa izinto zemvelo ezidingekayo ekukhuleni kweseli lomdlavuza. Isebenza ngokubulala noma ngokumisa ukukhula kwamangqamuzana omdlavuza.

I-Pegaspargase iza njengoketshezi oluzofakwa emsipheni noma lufakwe ngaphakathi (emthanjeni) ngaphezu kwamahora angu-1 kuya kwangu-2 ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma emtholampilo wabangalaliswa esibhedlela. Imvamisa inikezwa hhayi kaningi ngaphezu kwesisodwa njalo emavikini ama-2. Udokotela wakho uzokhetha uhlelo oluzokusebenzela kangcono ngokuya ngempendulo yakho emithini.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-pegaspargase,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-pegaspargase, asparaginase (Elspar), noma imuphi omunye umuthi, noma yiziphi izithako zomjovo we-pegaspargase. Buza usokhemisi wakho noma uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• Tshela udokotela wakho uma uke waba ne-pancreatitis (ukuvuvukala kwamanyikwe), amahlule egazi, noma ukuphuma kakhulu kwegazi, ikakhulukazi uma lokhu kwenzeka ngesikhathi sokwelashwa kwangaphambili nge-asparaginase (Elspar). Udokotela wakho cishe ngeke afune ukuthi uthole i-pegaspargase.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthola i-pegaspargase, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho nge-pegaspargase.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Pegaspargase ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• imfiva
• ukukhathala
• isiyezi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka kwesikhumba
• ukulunywa
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya
• ikhanda
• ukuvuvukala kobuso, izingalo, noma imilenze
• ukuquleka
• ubuhlungu besifuba
• ubuhlungu obuqhubekayo obuqala endaweni yesisu, kepha bungasabalala baye emuva
• ukuchama kaningi
• ukoma okwandisiwe

I-Pegaspargase ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuqubuka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-pegaspargase.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Oncaspar^®

• I-PEG-L-asparaginase