Ukujova kweGemcitabine

-Delile

• Ngaphambi kokuthola i-gemcitabine,
• IGemcitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Gemcitabine isetshenziswa ngokuhlangana ne-carboplatin ukwelapha umdlavuza we-ovarian (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda) okubuyise okungenani izinyanga eziyisithupha ngemuva kokuqeda ukwelashwa kwangaphambilini. Iphinde yasetshenziswa ihlangene ne-paclitaxel (i-Abraxane, iTaxol) ukwelapha umdlavuza webele ongathuthukile noma osuke wanda ngemuva kokwelashwa ngeminye imithi. I-Gemcitabine isetshenziswa ngokuhlangana ne-cisplatin ukwelapha uhlobo lomdlavuza wamaphaphu (non-small cell lung lung cancer; NSCLC) osusabalele kwezinye izingxenye zomzimba futhi ongeke welashwe ngokuhlinzwa. I-Gemcitabine nayo isetshenziselwa ukwelapha umdlavuza we-pancreatic osabalalele kwezinye izingxenye zomzimba futhi awuzange uthuthuke noma ube mubi ngemuva kokwelashwa ngomunye umuthi. IGemcitabine isekilasini lemithi ebizwa ngama-antimetabolite. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

IGemcitabine iza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphezulu kwemizuzu engama-30 ngemithambo (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Lapho i-gemcitabine isetshenziselwa ukwelapha umdlavuza we-ovari noma webele, imvamisa inikezwa ngezinsuku ezithile njalo emavikini amathathu. Lapho i-gemcitabine isetshenziselwa ukwelapha umdlavuza wamaphaphu, imvamisa inikezwa ngezinsuku ezithile njalo emavikini amathathu noma amane. Lapho i-gemcitabine isetshenziselwa ukwelapha umdlavuza we-pancreatic, ingajovwa kanye ngesonto. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza noma isimo onaso.Udokotela wakho angadinga ukuyeka noma ukubambezela ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Gemcitabine nayo kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza wesinye nomdlavuza womgudu we-biliary (umdlavuza ezithweni nasemadeleni enza futhi agcine inyongo, uketshezi olwenziwe isibindi). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-gemcitabine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-gemcitabine, noma imiphi eminye imithi, noma iziphi izithako ku-gemcitabine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• utshele udokotela wakho uma uphuza noma wake waphuza utshwala obuningi noma uma uke waba nesifo sesibindi, noma i-hepatitis, noma isifo sezinso.
• Tshela udokotela wakho uma uke wathola noma ngaphambilini uthola ukwelashwa ngemisebe.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Uma ungowesifazane, kuzodingeka uthathe ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa futhi usebenzise ukulawulwa kokubeletha okusebenzayo ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho futhi okungenani izinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha okusebenzayo ngenkathi nithola i-gemcitabine nezinyanga ezi-3 ngemuva komthamo wokugcina. Khuluma nodokotela wakho ngokusebenzisa ukuvimbela inzalo ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nge-gemcitabine. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola i-gemcitabine, shayela udokotela wakho. I-Gemcitabine ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ngenkathi uthola umjovo we-gemcitabine kanye neviki elingu-1 ngemuva komthamo wakho wokugcina.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala emadodeni. Khuluma nodokotela wakho ngezingozi zokuthola i-gemcitabine.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

IGemcitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• izilonda emlonyeni nasemphinjeni
• ukulahleka kwezinwele
• ikhanda
• imisipha ebuhlungu noma ebuhlungu
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ukuvuvukala, ubuhlungu, ubomvu, noma ukushisa endaweni yomjovo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukuqubuka, ukulunywa, isifuba, umphimbo noma ukuvuvukala kolimi, ukuphefumula okuncane, ubunzima bokuphefumula, ukuhlanza, ikhanda elikhanyayo, noma ukuquleka
• ukopha okungajwayelekile noma ukulimaza, izitulo ezilindile ezibomvu noma ezimnyama, noma ukukhwehlela noma ukuhlanza igazi noma okokusebenza okubukeka njengezizathu zekhofi
• izinguquko kumthamo womchamo
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
• ukukhathala okungajwayelekile noma ubuthakathaka, ukuphefumula okuncane, noma ukuphefumula
• ukuphuzi kwesikhumba noma kwamehlo, umchamo omnyama, ukulahlekelwa isifiso sokudla, ukukhathala, noma ubuhlungu noma ukungahambi kahle endaweni engaphezulu yesisu
• ukuvuvukala kwezinyawo, amaqakala, noma imilenze engezansi; ubuhlungu besisu; indle enamanzi; noma ukukhathala
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• ikhanda, ukuqubuka, ukukhathala, ukudideka, noma izinguquko zombono

I-Gemcitabine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuqhuma okukhulu
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ukopha okungajwayelekile noma ukulinyazwa
• okubomvu noma okumnyama, izitulo zokulinda
• umchamo obomvana, obomvu, noma onsundu
• ukukhwehlela noma ukuphalaza igazi noma into ebukeka njengezizathu zekhofi
• umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka
• ukukhathala ngokweqile

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-gemcitabine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UGemzar^®