UCelecoxib

-Delile

• Ngaphambi kokuthatha i-celecoxib,
• I-Celecoxib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungathathi enye i-celecoxib uze ukhulume nodokotela wakho.
• Izimpawu zokudlula ngokweqile zingafaka:

Abantu abathatha izidakamizwa ezingezona ukuvuvukala (ama-NSAID) (ngaphandle kwe-aspirin) njenge-celecoxib bangaba nengozi enkulu yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi kunabantu abangayithathi le mithi. Le micimbi ingenzeka ngaphandle kwesixwayiso futhi ingadala ukufa. Le ngozi ingahle ibe phezulu kubantu abathatha ama-NSAID isikhathi eside. Ungathathi i-NSAID efana ne-celecoxib uma usanda kuhlaselwa yinhliziyo, ngaphandle uma uqondiswe ngudokotela wakho ukuthi akwenze kanjalo. Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo senhliziyo, ehlaselwa yisifo senhliziyo, noma sohlangothi, uma ubhema, nokuthi ngabe uke waba ne-cholesterol ephezulu, umfutho wegazi ophakeme noma isifo sikashukela. Thola usizo lwezokwelapha oluphuthumayo ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: Ubuhlungu besifuba, ukuphefumula okuncane, ukuba buthakathaka engxenyeni eyodwa noma ohlangothini lomzimba, noma ukukhuluma okungaqinile.

Uma uzobe uhlolwa umthambo we-coronary bypass graft (CABG; uhlobo lokuhlinzwa kwenhliziyo), akufanele uthathe i-celecoxib ngaphambi noma ngemuva kokuhlinzwa.

Ama-NSAID afana ne-celecoxib angadala izilonda, ukuphuma kwegazi, noma izimbobo esiswini noma emathunjini. Lezi zinkinga zingakhula nganoma yisiphi isikhathi ngesikhathi sokwelashwa, zingenzeka ngaphandle kwezimpawu zokuxwayisa, futhi zingadala nokufa. Ingozi ingaba phezulu kubantu abathatha ama-NSAID isikhathi eside, sebekhulile ngeminyaka, benempilo ebuthaka, noma bephuza utshwala obuningi ngenkathi bethatha i-celecoxib. Tshela udokotela wakho uma uphuza kakhulu utshwala noma uma uphuza noma iyiphi yale mithi elandelayo: ama-anticoagulants ('blood thinner') afana ne-warfarin (i-Coumadin, i-Jantoven); i-aspirin; amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) noma naproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, e-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-sertraline (i-Zoloft); noma i-serotonin norepinephrine reuptake inhibitors (SNRIs) efana ne-desvenlafaxine (Pristiq), duloxetine (Cymbalta), ne-venlafaxine (Effexor XR). Phinda utshele udokotela wakho uma uke waba nezilonda noma wopha esiswini noma emathunjini noma kwezinye izifo zokopha. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, yeka ukuthatha i-celecoxib bese ushayela udokotela wakho: ubuhlungu besisu, isilungulela, ukuhlanza into enegazi noma ebukeka njengezizathu zekhofi, igazi elisesitokisini, noma izitulo ezimnyama nezokulinda.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoqapha izimpawu zakho ngokucophelela futhi mhlawumbe uzo-oda izivivinyo ezithile ukuhlola impendulo yomzimba wakho ku-celecoxib. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ukuze udokotela wakho akwazi ukukubeka inani elifanele lemithi yokwelapha isimo sakho ngengozi ephansi kakhulu yemiphumela emibi kakhulu.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-celecoxib futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

I-Celecoxib isetshenziselwa ukuqeda ubuhlungu, isizotha, ukuvuvukala nokuqina okubangelwa i-osteoarthritis (i-arthritis ebangelwa ukuwohloka kolwelwesi lwamajoyini), isifo samathambo (isifo samathambo esibangelwa ukuvuvukala kolwelwesi lwamalunga), kanye ne-ankylosing spondylitis (isifo samathambo kuthinta kakhulu umgogodla). I-Celecoxib isetshenziselwa ukwelapha i-juvenile rheumatoid arthritis (uhlobo lwe-arthritis oluthinta izingane) ezinganeni ezineminyaka emibili nangaphezulu. ICelecoxib ibuye isetshenziselwe ukwelapha izikhathi zokuya esikhathini ezibuhlungu nokukhulula ezinye izinhlobo zobuhlungu besikhashana obufaka phakathi ubuhlungu obubangelwa ukulimala, ukuhlinzwa nezinye izinqubo zezokwelapha noma zamazinyo, noma izimo zezokwelapha ezihlala isikhathi esilinganiselwe. UCelecoxib usesigabeni sama-NSAID abizwa nge-COX-2 inhibitors. Isebenza ngokumisa ukukhiqizwa komzimba wento ebangela ubuhlungu nokuvuvukala.

ICelecoxib iza njengephilisi elizothathwa ngomlomo. Ama-capsule we-Celecoxib ngokuvamile athathwa kanye noma kabili ngosuku. Uma uthatha ama-200 mg wamaphilisi we-celecoxib ngasikhathi, ungathatha umuthi ngokudla noma ngaphandle kokudla.Uma uthatha ngaphezu kwama-200 mg wamaphilisi we-celecoxib ngasikhathi, kufanele uphuze umuthi ngokudla. Buza udokotela noma usokhemisi wakho uma ungenaso isiqiniseko sokuthi udinga ukuthatha imithi yakho ngokudla. Ukukusiza ukuthi ukhumbule ukuthatha ama-celecoxib capsules, thatha wona ngasikhathi sinye nsuku zonke.

Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-celecoxib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma ungeke ukwazi ukuwagwinya amaphilisi noma uma unikeza ingane le mithi, ungavula ama-capsule ufafaze okuqukethwe ngaphezulu kwetispuni le-appleauce ebandayo noma ekamelweni lokushisa. Ungayilungisa ingxube kusengaphambili bese uyigcina kuze kufike emahoreni ayisithupha esiqandisini. Lapho usukulungele ukuthatha imishanguzo yakho, gwinya yonke le ngxube. Bese uphuza amanzi ukugeza ingxube bese uqiniseka ukuthi uwugwinyile wonke.

I-Celecoxib kwesinye isikhathi isetshenziswa ngokuhlinzwa nezinye izindlela zokwelapha ukunciphisa inani lama-polyp (ukukhula okungajwayelekile) kukholoni (amathumbu amakhulu) kanye ne-rectum ezigulini ezinomndeni adenomatous polyposis (isimo lapho amakhulu noma izinkulungwane zama-polyps akha ikholoni futhi umdlavuza ungavela). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-celecoxib,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-celecoxib, i-aspirin noma amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) ne-naproxen (i-Aleve, iNaprosyn), imishanguzo ye-sulfa, noma imuphi omunye umuthi, noma yiziphi izithako ezingasebenzi kuma-capsule e-celecoxib Buza usokhemisi wakho ukuthola uhlu lwezithako ezingasebenzi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: ama-enzyme aguqula i-angiotensin (ACE) anjenge-benazepril (Lotensin, eLotrel), i-captopril, i-enalapril (Epaned, Vasotec, e-Vaseretic), lisinopril (Qbrelis, in Zestoretic), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), kanye netrandolapril (eTarka); ama-angiotensin receptor blockers anjenge-candesartan (Atacand, e-Atacand HCT), eprosartan, irbesartan (Avapro, e-Avalide), losartan (Cozaar, eHyzaar), olmesartan (Benicar, e-Azor, eBenicar HCT, eTribenzor), telmisartan Micard , eMicardis HCT, eTwynsta), nase-valsartan (Dioavan, e-Entresto, e-Exforge HCT); i-atomoxetine (iStrattera); ama-beta blocker anjenge-atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Kapspargo Sprinkle, Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kanye nepropranolol (Hemangeol, Inderal, Innopran); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-digoxin (i-Lanoxin); isisu (‘amaphilisi amanzi’); i-fluconazole (iDiflucan); i-lithium (i-Lithobid); i-methotrexate (i-Otrexup, i-Rasuvo, i-Reditrex, i-Trexall); futhi pemtrexed (Alimta, Pemfexy). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-celecoxib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi yezimo okukhulunywe ngazo esigabeni ESIBALULEKILE SESEXWAYISO noma isifuba somoya, ikakhulukazi uma unamakhala agxishiwe kaningi noma agijimayo noma ama-polyp acinene (ukuvuvukala kolwelwesi lwekhala); ukuvuvukala kwezandla, izingalo, izinyawo, amaqakala, noma imilenze engezansi; ukwehluleka kwenhliziyo; noma isifo sesibindi noma sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa; noma ukuncelisa ibele. I-Celecoxib ingalimaza umbungu futhi idale izinkinga ngokulethwa uma ithathwa cishe amasonto angama-20 noma kamuva ngesikhathi sokukhulelwa. Ungathathi i-celecoxib ezungeze noma ngemuva kwamasonto angama-20 ukhulelwe, ngaphandle kokuthi utshelwe ngudokotela wakho ukuthi wenze njalo. Uma ukhulelwa ngenkathi uthatha i-celecoxib, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-celecoxib.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uthatha i-celecoxib, thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Celecoxib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• igesi noma ukuqunjelwa
• Umphimbo obuhlungu
• izimpawu ezibandayo
• ukuqunjelwa
• isiyezi
• i-dysgeusia

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungathathi enye i-celecoxib uze ukhulume nodokotela wakho.

• ukuzuza kwesisindo okungaqondakali
• ukuphefumula okuncane noma ukuphefumula kanzima
• ukuvuvukala kwesisu, izinyawo, amaqakala noma imilenze engezansi
• isifo sohudo
• isicanucanu
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ukulunywa
• ukungabi namandla
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• amabhamuza
• imfiva
• ukuqubuka
• isifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, noma izandla
• ukushaqeka
• ubunzima bokugwinya noma ukuphefumula
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• kunamafu, umbala ogqamile, noma umchamo onegazi
• ukuhlungu obusemhlane
• ukuchama okunzima noma okubuhlungu
• ukuchama njalo, ikakhulukazi ebusuku

I-Celecoxib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukungabi namandla
• ukozela
• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• izinto zokuhlanza ezinegazi noma ezibukeka njengezizathu zekhofi
• ezinegazi noma ezimnyama, izitulo zokulinda
• ukulahlekelwa ukwazi
• isifuba
• ukuqubuka
• ukuvuvukala kwamehlo, ubuso, ulimi, izindebe, umphimbo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuphefumula kanzima noma ukugwinya

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Umfutho wegazi lakho kufanele uhlolwe njalo ngesikhathi sokwelashwa kwakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UCelebrex^®
• Elyxyb^®¶

• Consensi^® (equkethe i-Amlodipine, Celecoxib)

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.