Ukwelapha umfutho wegazi ophezulu ngamaCalcium Channel Blockers

-Delile

• Ngubani okufanele athathe izivimbeli zesiteshi se-calcium?
• Isebenza kanjani i-calcium channel blocker
• Izinhlobo zemithi evimba i-calcium channel
• Iyini imiphumela emibi nezingozi?
• Izivimbeli zesiteshi se-calcium yemvelo

Yini ama-block blocker e-calcium?

Ama-calcium channel blockers (CCBs) ayisigaba semithi esetshenziselwa ukwelapha umfutho wegazi ophezulu. Babizwa nangokuthi abaphikisana ne-calcium. Zisebenza kahle njenge-ACE inhibitors ekwehliseni umfutho wegazi.

Ngubani okufanele athathe izivimbeli zesiteshi se-calcium?

Udokotela wakho angakunika ama-CCB uma une:

• umfutho wegazi ophakeme
• ukushaya kwenhliziyo okungajwayelekile okubizwa ngokuthi ama-arrhythmias
• ubuhlungu besifuba obuhlobene ne-angina

Umfutho wegazi ophezulu nawo ungalashwa ngezinye izinhlobo zemithi. Udokotela wakho angakunika kokubili i-CCB nomunye umuthi ophakeme kakhulu ngesikhathi esisodwa.

Imihlahlandlela emisha kakhulu evela e-American College of Cardiology incoma ukuthi i-ACE inhibitors, diuretics, angiotensin-receptor blockers (ARBs), kanye namaCCB kube yimithi yokuqala okufanele icatshangelwe uma welapha umfutho wegazi ophezulu. Amaqembu athile abantu angazuza ikakhulukazi kumaCCB ngokuhambisana neminye imithi, kufaka phakathi:

• Abantu base-Afrika baseMelika
• abantu abanesifo sezinso
• asebekhulile
• abantu abanesifo sikashukela

Isebenza kanjani i-calcium channel blocker

Ama-CCB anciphisa umfutho wegazi ngokunciphisa inani le-calcium noma izinga lapho i-calcium igeleza ingene enhlizweni yemisipha yenhliziyo nezindonga zamangqamuzana emithambo yegazi. I-calcium ivuselela inhliziyo ukuthi isebenze ngamandla amakhulu. Lapho ukugeleza kwe-calcium kunqunyelwe, ukusikwa kwenhliziyo yakho akunamandla ngokushaya ngakunye, futhi imithambo yegazi yakho iyakwazi ukukhululeka. Lokhu kuholela ekwehliseni umfutho wegazi.

Ama-CCB ayatholakala ngezinhlobo eziningi zezakhiwo zomlomo, kusuka kumaphilisi wokuqothula amancanyana afinyelela kumaphilisi akhishwa isikhathi eside. Umthamo uzoncika kumlando wakho wezempilo nowezokwelapha. Udokotela wakho uzobuye acabangele iminyaka yakho ngaphambi kokunikeza umuthi wokwehlisa umfutho wegazi. Ama-CCBs kaningi mancane amathuba okuthi abangele imiphumela emibi kubantu abaneminyaka engaphezu kwengama-65.

Izinhlobo zemithi evimba i-calcium channel

Izigaba ezintathu eziyinhloko zezidakamizwa zeCCB zisuselwa ekwakhiweni kwazo kwamakhemikhali nomsebenzi:

• Ama-dihydropyridines. Lokhu kusebenza ikakhulu emithanjeni yegazi.
• I-Benzothiazepines. Lokhu kusebenza kumisipha yenhliziyo nemithambo yegazi.
• Ama-phenylalkylamines. Lokhu kusebenza ikakhulu emisipheni yenhliziyo.

Ngenxa yesenzo sabo, ama-dihydropyridines asetshenziswa kakhulu ekwelapheni umfutho wegazi ophezulu kunezinye izigaba. Lokhu kungenxa yekhono labo lokunciphisa ingcindezi yemithambo yegazi nokumelana nemithambo yegazi. Abamelene ne-dihydropyridine calcium bavame ukuphela kusijobelelo “-pine” futhi bafake:

• i-amlodipine (i-Norvasc)
• i-felodipine (Plendil)
• umabhebhana
• i-nicardipine (Cardene)
• i-nifedipine (Adalat CC)
• i-nimodipine (Nymalize)
• sifiso

Amanye ama-CCB ajwayele ukwelashwa asetshenziselwa ukwelapha ukushaya kwenhliziyo kwe-angina nokungajwayelekile yi-verapamil (Verelan) ne-diltiazem (iCardizem CD).

Iyini imiphumela emibi nezingozi?

Ama-CCB angaxhumana nezinye izidakamizwa noma izengezo ozithathayo. Qiniseka ukuthi udokotela wakho unohlu olusha lwayo yonke imithi yakho, amavithamini, kanye nezithako zemithi.

Ama-CCB nemikhiqizo yamagilebhisi, kufaka phakathi izithelo kanye nejusi, akufanele kuthathwe ndawonye. Imikhiqizo yamagilebhisi iphazamisa ukukhishwa okujwayelekile komuthi. Kungaba yingozi uma inani elikhulu lomuthi lihlangana emzimbeni wakho. Linda okungenani amahora amane ngemuva kokuthi uthathe imishanguzo yakho ngaphambi kokuphuza ijusi lamagilebhisi noma udle ubhamubhamu.

Imiphumela emibi yamaCCB ifaka phakathi:

• isiyezi
• ikhanda
• ukuqunjelwa
• isilungulela
• isicanucanu
• ukuqubuka kwesikhumba noma ukuqhuma, okungububomvu ebusweni
• ukuvuvukala emaphethelweni aphansi
• ukukhathala

Amanye ama-CCB anciphisa amazinga kashukela egazini kwabanye abantu. Tshela udokotela wakho nganoma yimiphi imiphumela emibi obhekene nayo. Bangase balungise isilinganiso sakho noma bancome ukuthi ushintshele komunye umuthi uma imiphumela emibi ithatha isikhathi eside, ingathandeki, noma isongela impilo yakho.

Izivimbeli zesiteshi se-calcium yemvelo

I-Magnesium yisibonelo sesakhi esisebenza njengeCCB yemvelo. Ucwaningo lukhombisile ukuthi amazinga aphezulu we-magnesium avimba ukuhamba kwe-calcium. Ezifundweni zezilwane, ukwesekwa kwe-magnesium kubonakala kusebenza kakhulu kwabancane abanomfutho wegazi ophakeme, ngaphambi kokuba babe nomfutho wegazi ophezulu. Kubuye kwabonakala kwehlisa ukukhula komfutho wegazi ophezulu. Ukudla okunothe nge-Magnesium kufaka:

• irayisi elinsundu
• ama-alimondi
• amakinati
• cashews
• i-oat bran
• okusanhlamvu okusanhlamvu okusikiwe
• isoya
• ubhontshisi omnyama
• ubhanana
• isipinashi
• ukwatapheya

Buza udokotela wakho ukuthi ukudla ukudla okune-magnesium kuzothinta yini amandla we-CCB owathathayo.