Umlobi: William Ramirez
Usuku Lokudalwa: 19 Usepthemba 2021
Ukuvuselela Usuku: 16 Unovemba 2024
Anonim
Pioglitazone, Rosiglitazone, and Troglitazone - Thiazolidinediones / Glitazones
Ividiyo: Pioglitazone, Rosiglitazone, and Troglitazone - Thiazolidinediones / Glitazones

-Delile

I-Rosiglitazone neminye imishanguzo efanayo yesifo sikashukela ingadala noma yenze ukwehluleka kwenhliziyo ukuminyana (isimo lapho inhliziyo ingakwazi ukupompa igazi elanele kwezinye izingxenye zomzimba). Ngaphambi kokuba uqale ukuthatha i-rosiglitazone, tshela udokotela wakho uma uke waba nokuhluleka kwenhliziyo okucinana, ikakhulukazi uma ukwehluleka kwenhliziyo yakho kunzima kakhulu ukuthi kufanele ukhawule umsebenzi wakho futhi unethezeke kuphela lapho uphumule noma kufanele uhlale isihlalo noma umbhede. Phinda utshele udokotela wakho uma ngabe wazalwa unenkinga yenhliziyo, futhi uma uke waba nokuvuvukala kwezingalo, izandla, izinyawo, amaqakala noma imilenze engezansi; isifo senhliziyo, umfutho wegazi ophakeme; isifo semithambo yegazi (ukuncipha kwemithambo yegazi eholela enhliziyweni); isifo senhliziyo; ukushaya kwenhliziyo okungajwayelekile; noma ukuphefumula ubuthongo. Udokotela wakho angakutshela ukuthi ungathathi i-rosiglitazone noma angakuqapha ngokucophelela ngesikhathi sokwelashwa kwakho.

Uma uhlakulela ukuhluleka kwenhliziyo okuminyene, ungahlangabezana nezimpawu ezithile. Tshela udokotela wakho ngokushesha uma unezinye zalezi zimpawu ezilandelayo, ikakhulukazi lapho uqala ukuthatha i-rosiglitazone noma ngemuva kokuba umthamo wakho wanda: ukuzuza okukhulu kwesisindo ngesikhathi esifushane; ukuphelelwa umoya; ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukuvuvukala noma ubuhlungu esiswini; ukuvuka ukuphefumula ebusuku; udinga ukulala ngemicamelo eyengeziwe ngaphansi kwekhanda lakho ukuze uphefumule ngenkathi ulele phansi; ukukhwehlela njalo noma ukoma; ubunzima bokucabanga kahle noma ukudideka; ukushaya kwenhliziyo okusheshayo noma okugijimayo; ukungakwazi ukuhamba noma ukuzivocavoca futhi; noma ukukhathala okwandisiwe.


Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-rosiglitazone futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha.

Khuluma nodokotela wakho ngezingozi zokuthatha i-rosiglitazone.

I-Rosiglitazone isetshenziswa kanye nohlelo lokudla nokuzivocavoca futhi kwesinye isikhathi isebenzisa umuthi owodwa noma ngaphezulu ukwelapha uhlobo lwesifo sikashukela sohlobo lwesibili (isimo lapho umzimba ungasebenzisi i-insulin ngokujwayelekile ngakho-ke awukwazi ukulawula inani likashukela egazini). I-Rosiglitazone isekilasini lemithi ebizwa ngokuthi i-thiazolidinediones. Isebenza ngokwandisa ukuzwela komzimba kwi-insulin, into yemvelo esiza ukulawula amazinga kashukela egazini. I-Rosiglitazone ayisetshenziselwa ukwelapha isifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma i-ketoacidosis yesifo sikashukela (isimo esibi kakhulu esingavela uma ushukela wegazi ongelashwa).


Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukuthatha imishanguzo, ukwenza ushintsho endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca umzimba, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela nokuthuthukisa impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-Rosiglitazone iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye noma kabili ngosuku noma ngaphandle kokudla. Thatha i-rosiglitazone cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-rosiglitazone njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.


Udokotela wakho angakhuphula umthamo wakho we-rosiglitazone ngemuva kwamaviki ayi-8-12, ngokuya ngempendulo yomzimba wakho emithini.

I-Rosiglitazone isiza ukulawula uhlobo lwesifo sikashukela sohlobo lwesibili kodwa ayiselaphi. Kungathatha amasonto ama-2 ukuthi ushukela wegazi wehle, nezinyanga ezingama-2-3 noma ngaphezulu ukuze uzwe inzuzo ephelele ye-rosiglitazone. Qhubeka uthathe i-rosiglitazone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-rosiglitazone ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-rosiglitazone,

  • Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-rosiglitazone, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-rosiglitazone. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: gemfibrozil (Lopid); i-insulin noma eminye imithi yesifo sikashukela; imishanguzo yomfutho wegazi ophakeme, i-cholesterol ephezulu, ukwehluleka kwenhliziyo, noma ukuvimbela isifo senhliziyo noma isifo sohlangothi; kanye ne-rifampin (Rifadin, Rimactane, eRifamate). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SESEXWAYISO noma isifo samehlo esifo sikashukela njenge-macular edema (ukuvuvukala ngemuva kweso); noma isifo sesibindi. Phinda utshele udokotela wakho uma wake wathatha i-troglitazone (i-Rezulin, engasatholakali e-United States), ikakhulukazi uma uyeka ukuyithatha ngoba uhlangabezana nemiphumela engemihle.
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-rosiglitazone, shayela udokotela wakho.
  • uma ungakabi nesikhathi sokunqamuka kokuya esikhathini (ushintsho lwempilo, ukuphela kwezikhathi zokuya esikhathini njalo ngenyanga) kufanele wazi ukuthi i-rosiglitazone ingakhuphula amathuba okuthi ukhulelwe noma ungenazo izikhathi ezijwayelekile zanyanga zonke noma unesimo esikuvimbela ukuvuthisa (ukukhulula iqanda kuma-ovari). Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Kubalulekile ukudla ukudla okunempilo, ukuzivocavoca umzimba njalo, nokunciphisa isisindo uma kunesidingo. Lokhu kuzosiza ukulawula isifo sakho sikashukela futhi kusize i-rosiglitazone isebenze kahle

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-Rosiglitazone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ikhanda
  • ukuphuma kwamakhala nezinye izimpawu ezibandayo
  • Umphimbo obuhlungu
  • ukuhlungu obusemhlane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

  • ubuhlungu emhlathini, engalweni, emuva, entanyeni, noma esiswini
  • ubuhlungu besifuba
  • kuqhume umjuluko obandayo
  • ubumhlophe
  • ukulahlekelwa isifiso sokudla
  • isicanucanu
  • ukuhlanza
  • ubuhlungu besisu
  • umchamo omnyama
  • ukuphuzi kwesikhumba noma kwamehlo
  • izinguquko embonweni
  • ukulahleka kombono
  • isikhumba esiphaphathekile
  • isiyezi
  • ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
  • ukushaqeka
  • ubunzima bokugwinya noma ukuphefumula
  • isifuba
  • ukulunywa
  • imfiva
  • amabhamuza

I-Rosiglitazone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma uhlangabezana nezinkinga ezingavamile ngenkathi uthatha lo muthi.

Ukuthatha i-rosiglitazone kungakhuphula ubungozi bokuthi uzoqhekeka, imvamisa ezingalweni eziphezulu, ezandleni noma ezinyaweni. Khuluma nodokotela wakho ngengozi yokuphuza le mithi nangezindlela zokugcina amathambo akho enempilo ngesikhathi sokwelashwa kwakho.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile, nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho, udokotela wamehlo wakho kanye nelabhorethri. Udokotela wakho mhlawumbe uzo-oda ukuhlolwa njalo kwamehlo nokuhlolwa okuthile kwelabhorethri ukuze ahlole impendulo yomzimba wakho ku-rosiglitazone. Ushukela wegazi kanye ne-hemoglobin yakho ene-glycosylated kufanele ihlolwe njalo ukuthola impendulo yakho ku-rosiglitazone. Udokotela wakho angakutshela nokuthi ungayihlola kanjani impendulo yakho ku-rosiglitazone ngokulinganisa amazinga kashukela egazini lakho ekhaya. Landela lezi zinkomba ngokucophelela.

Kufanele njalo ufake isongo lokuhlonza isifo sikashukela ukuze uqiniseke ukuthi uthola ukwelashwa okufanele esimeni esiphuthumayo.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • I-Avandia®
  • I-Avandamet® (equkethe iMetformin, iRosiglitazone)
  • Avandaryl® (equkethe iGlimepiride, Rosiglitazone)
Kugcine ukubuyekezwa - 01/15/2018

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