Umlobi: William Ramirez
Usuku Lokudalwa: 20 Usepthemba 2021
Ukuvuselela Usuku: 12 Unovemba 2024
Anonim
Rabeprazole - Mechanism of Action
Ividiyo: Rabeprazole - Mechanism of Action

-Delile

I-Rabeprazole isetshenziselwa ukwelapha izimpawu zesifo se-reflux se-gastroesophageal (GERD), okuyisimo lapho ukubuyela emuva kwe-asidi esiswini kubangela ukushaya kwenhliziyo nokulimala okungenzeka kwesisu (ithubhu elihlanganisa umphimbo nesisu) kubantu abadala nezingane unyaka owodwa yobudala nangaphezulu. I-Rabeprazole isetshenziselwa ukwelapha umonakalo ovela ku-GERD, ivumele ukuqabhuka kwesikhumba, futhi ivimbele okunye ukulimala kwabantu abadala. I-Rabeprazole ibuye isetshenziselwe ukwelapha izimo lapho isisu sikhiqiza khona i-asidi eningi, njenge-Zollinger-Ellison syndrome kubantu abadala. I-Rabeprazole isetshenziselwa ukwelapha izilonda (izilonda ngaphakathi kolwelwesi lwesisu noma lwamathumbu) futhi isetshenziswa ngokuhlangana neminye imithi yokuqeda H. pylori (igciwane elibanga izilonda) kubantu abadala. URabeprazole usesigabeni semithi ebizwa nge-proton-pump inhibitors. Isebenza ngokunciphisa inani le-asidi eyenziwe esiswini.

URabeprazole uza njengokukhishwa okubambezelekile (kukhipha umuthi emathunjini ukuvimbela ukwephuka kwemithi ngama-acid esiswini) ithebhulethi kanye ne-capsule efafaza ukukhishwa (capsule equkethe ama-granules amancane emithi afafazwa ekudleni noma ketshezi) ukuthatha ngomlomo. Amathebulethi okukhishwa okubambezelekile ngokuvamile athathwa kanye ngosuku. Uma isetshenziselwa ukwelapha izilonda, amaphilisi e-rabeprazole athathwa ngemuva kwesidlo sasekuseni. Lapho isetshenziswa ngokuhlangana neminye imithi ukuqeda H. pylori, amaphilisi e-rabeprazole athathwa kabili ngosuku, nokudla kwasekuseni nakusihlwa, izinsuku ezi-7. Amaphilisi we-Rabeprazole afafaza imvamisa athathwa kanye ngosuku ngemizuzu engama-30 ngaphambi kokudla. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-rabeprazole njengoba nje iyalelwe. Ungayithathi ngaphezulu noma ngaphansi kwayo noma uyithathe kaningi noma isikhathi eside kunokuyalelwa ngudokotela wakho.


Gwinya amaphilisi wonke ngamanzi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Ukuze uthathe amaphilisi wokufafaza, vula i-capsule bese ufafaza ama-granules entweni encane yokudla okuthambile okufana ne-appleauce, izithelo noma ukudla kwezingane zemifino, noma iyogathi bese ugwinya ingxube ngokushesha (kungakapheli imizuzu eyi-15) ngaphandle kokuhlafuna noma ukuchoboza ama-granules. Ungavula futhi i-capsule bese uthela okuqukethwe kuketshezi elipholile elifana nefomula yezinsana, ijusi le-apula, noma isisombululo se-electrolyte yezingane bese ugwinya ingxube ngokushesha (kungakapheli imizuzu eyi-15) ngaphandle kokuhlafuna noma ukuchoboza ama-granules.

Qhubeka nokuphuza i-rabeprazole noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-rabeprazole ngaphandle kokukhuluma nodokotela wakho. Uma isimo sakho singathuthuki noma siba sibi kakhulu, shayela udokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-rabeprazole,

  • Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-rabeprazole, dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid, Previpac), omeprazole (Prilosec, eZegerid), pantoprazole (Protonix), noma imuphi omunye umuthi, noma yimuphi omunye umuthi izithako ezisemaphilisi e-rabeprazole noma ama-capsules afafazwe. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho uma uthatha i-rilpivirine (i-Edurant, eComplera, e-Odefsey). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-rabeprazole uma uphuza lo muthi.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-antibiotic athile, ama-anticoagulants ('ama-blood thinner') afana ne-warfarin (Coumadin), atazanavir (Reyataz), cyclosporine (Neoral, Sandimmune), dasatinib (Sprycel), digoxin (Lanoxin), diuretics ( 'amaphilisi amanzi', erlotinib (Tarceva), itraconazole (Onmel, Sporonox), ketoconazole (Nizoral), izengezo zensimbi, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept), nelfinavir (Viracept), nilotinib (Tasignair) (Invirase), kanye ne-tacrolimus (Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
  • Tshela udokotela wakho uma uke waba nezinga eliphansi le-magnesium egazini lakho, amazinga aphansi kavithamini B-12 emzimbeni wakho, i-osteoporosis, isifo se-autoimmune (isimo lapho umzimba uhlasela khona izitho zawo, ubangele ukuvuvukala nokulahleka of function) njenge-systemic lupus erythematosus, noma isifo sesibindi.
  • utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-rabeprazole, shayela udokotela wakho.
  • khuluma nodokotela wakho ngezingozi nezinzuzo zokuthatha i-rabeprazole uma uneminyaka engama-70 noma ngaphezulu. Ungathathi lo muthi isikhathi eside kunokunconywa ngudokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.


Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Rabeprazole ingadala imiphumela emibi. Tshela udokotela wakho uma lezi zimpawu zinzima noma zingapheli:

  • ikhanda
  • isicanucanu
  • ukuhlanza
  • ukuqunjelwa
  • isifo sohudo
  • igesi
  • Umphimbo obuhlungu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha, noma uthole usizo oluphuthumayo lwezokwelapha:

  • isikhumba esishayayo noma esikhanyayo
  • ukuqubuka
  • isifuba
  • ukuvuvukala kwamehlo, ubuso, umlomo, izindebe, ulimi, noma umphimbo
  • ukuphefumula kanzima noma ukugwinya
  • ukushaya kwenhliziyo okungajwayelekile, okusheshayo, noma okushaya ngamandla
  • ukukhathala ngokweqile
  • isiyezi
  • ubumhlophe
  • ukuphazamiseka kwemisipha, amajaqamba, noma ubuthakathaka
  • jitteriness
  • ukuzamazama okungalawuleki kwengxenye yomzimba
  • isithuthwane
  • uhudo olunzima olunezitokisi ezinamanzi, ubuhlungu besisu, noma umkhuhlane ongapheli
  • ukuqubuka ezihlathini noma ezingalweni ezizwela ukukhanya kwelanga
  • ukwanda noma ukwehla kokuchama, igazi emchameni, ukukhathala, isicanucanu, ukulahlekelwa isifiso sokudla, umkhuhlane, ukuqubuka, noma ubuhlungu bamalunga

I-Rabeprazole ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.


Abantu abathatha ama-proton pump inhibitors afana ne-rabeprazole kungenzeka babe nethuba lokuphuka izihlakala, okhalweni noma umgogodla kunabantu abangathathi omunye wale mithi. Abantu abathatha ama-proton pump inhibitors bangahle bathuthukise ama-fundic gland polyps (uhlobo lokukhula esiswini). Lezi zingozi ziphezulu kakhulu kubantu abathatha imithamo ephezulu yomunye wale mithi noma bayiphuze unyaka owodwa noma ngaphezulu. Khuluma nodokotela wakho ngengozi yokuthatha i-rabeprazole.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zaselabhorethri ngaphambi nangesikhathi sokwelashwa kwakho, ikakhulukazi uma unesifo sohudo esibi.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-rabeprazole.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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Kugcine ukubuyekezwa - 02/15/2021

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