I-Alirocumab (Okubalulekile)

-Delile

• Izinkomba ze-Alirocumab (Okubalulekile)
• Izikhombisi-ndlela zokusetshenziswa kwe-Alirocumab (Okubalulekile)
• Imiphumela emibi ye-Alirocumab (Okubalulekile)
• Ukungafani kwe-Alirocumab (Okubalulekile)
• Ungayithenga kuphi i-Alirocumab (Okubalulekile)

I-Alirocumab umuthi osebenzela ukunciphisa i-cholesterol futhi, ngenxa yalokho, wehlisa ubungozi bezifo zenhliziyo ezifana nokuhlaselwa yisifo senhliziyo noma isifo sohlangothi.

I-Alirocumab umuthi ojojoweka kalula ongawusebenzisa ekhaya, oqukethe i-anti-body ekwazi ukuvimbela ukusebenza kwe-PSCK9, i-enzyme evimbela ukuthi i-cholesterol embi isuswe egazini.

Izinkomba ze-Alirocumab (Okubalulekile)

I-Alirocumab ikhonjiswa ezimweni zeziguli ezine-cholesterol ephezulu yemvelaphi yokuzalwa noma kulabo i-cholesterol enganciphi ngokwanele ngokusetshenziswa kwemithi ejwayelekile, njengeSimvastatin noma ngomthamo wayo omkhulu ovunyelwe.

Izikhombisi-ndlela zokusetshenziswa kwe-Alirocumab (Okubalulekile)

Imvamisa umjovo owodwa we-75mg ukhonjiswa njalo ezinsukwini eziyi-15, kepha udokotela angakhuphula umthamo ube ngu-150mg njalo ezinsukwini eziyi-15 uma kudingeka ukunciphisa amazinga we-cholesterol ngaphezu kuka-60%. Umjovo ungasetshenziswa ngokunqamula ethangeni, esiswini noma engalweni, kubalulekile ukushintsha izingosi zokufaka isicelo.

Imijovo ingahlinzekwa ngumuntu noma umnakekeli ngemuva kwencazelo kadokotela, umhlengikazi noma usokhemisi kodwa kulula ukuthi isetshenziswe ngoba iqukethe ipeni eligcwaliswe ngaphambili lokusetshenziswa kanye.

Imiphumela emibi ye-Alirocumab (Okubalulekile)

Ukusabela okweqile njengokulunywa, i-nummular eczema ne-vasculitis kungavela futhi indawo yomjovo ingavuvukala futhi ibe buhlungu. Ngaphezu kwalokho, kujwayelekile ukuthi izimpawu zivele ohlelweni lokuphefumula njengokuthimula kanye nokuthimliswa.

Ukungafani kwe-Alirocumab (Okubalulekile)

Lo muthi awukhonjisiwe ezinganeni nasebusheni kuze kube yiminyaka eyi-18, kanye nabesifazane abakhulelwe ngoba ukuhlolwa kokuphepha akukwenziwanga kulezi zimo. Kuyaphikiswa futhi ngesikhathi sokuncelisa ngoba kudlula obisini lwebele,

Ungayithenga kuphi i-Alirocumab (Okubalulekile)

I-Alirocumab umuthi onegama lokuhweba lePraluent, ohlolwa ngamalabhorethri eSanofi naseRegeneron, futhi awukatholakali ukuthengiselwa umphakathi.

Imvamisa, amakhambi ajwayelekile we-cholesterol, njenge-simvastatin, andisa ukukhiqizwa kwe-PSCK9 futhi, ngakho-ke, ngemuva kwesikhathi esithile, umuthi awusebenzi kangako ekwehliseni i-cholesterol. Ngakho-ke, i-Alirocumab ingasetshenziselwa ukugcwalisa ukwelashwa ngalolu hlobo lomuthi, ngaphezu kokukwazi ukusetshenziswa njengokwelashwa okukodwa ezigulini ezingakwazi ukunciphisa i-cholesterol ngemithi ejwayelekile.

Bheka ukuthi ungayigcwalisa kanjani le ndlela yokulawula i-cholesterol egazini:

• Ikhambi Le-cholesterol
• Ukudla okwehlisa i-cholesterol