Buza Isazi: Hlala Phansi neGastro
-Delile
- Kungenzeka yini ukuthi ungaxilongwa kahle nge-ulcerative colitis (UC)? Ngizokwazi kanjani uma kungukuxilongwa okungalungile noma ukuthi ngidinga ukwelashwa okwehlukile?
- Yiziphi izinkinga ze-UC engalashwa noma engaphathwa kahle?
- Yiziphi izinketho zokwelashwa ezitholakalayo ze-UC? Ngabe zikhona ezinye ezisebenza kangcono kunezinye?
- Ama-anti-inflammatories
- Imithi elwa namagciwane
- Ama-immunosuppressors
- Izindlela zokwelapha ze-Biologic
- Ingabe kunemiphumela engemihle yemithi okufanele ngiyazi?
- Izidakamizwa ezilwa nokuvuvukala
- Imithi elwa namagciwane
- Ama-immunosuppressors
- Izindlela zokwelapha ze-Biologic
- Ngizokwazi kanjani uma ukwelashwa kwami kungasebenzi kahle?
- Yiziphi izimbangela ezivamile ze-UC?
- Kuvame kangakanani i-UC? Ama-IBD? Ingabe kuwufuzo?
- Ingabe kukhona amakhambi emvelo e-UC? Ezinye izindlela zokwelapha? Ingabe ziyasebenza?
- Amakhambi ezokudla
- Amakhambi esintu
- Ukuphathwa kwengcindezi
- Ukuzivocavoca umzimba
- Ingabe kufanele ngicabange ngokuhlinzwa?
- Ungalutholaphi ulwazi oluthe xaxa nge-UC noma uthole ukwesekwa kubantu nabo abaphila nalesi simo?
Kungenzeka yini ukuthi ungaxilongwa kahle nge-ulcerative colitis (UC)? Ngizokwazi kanjani uma kungukuxilongwa okungalungile noma ukuthi ngidinga ukwelashwa okwehlukile?
Abantu bavame ukudida i-UC nesifo sikaCrohn. ICrohn's futhi iyisifo esivamile sokuvuvukala kwamathumbu (IBD). Izimpawu ezimbalwa ziyefana, njengokuxolelwa kanye nama-flare-ups.
Ukunquma ukuthi unayo yini i-UC noma i-Crohn's, vakashela udokotela wakho bese uhlolwa. Kungase kudingeke ukuthi uphinde uphinde uphendule i-colonoscopy, noma udokotela angayalela i-X-ray yamathumbu amancane ukuze ahlole ukuthi ayithintekile yini. Uma ikhona, ungaba nesifo sikaCrohn. I-UC ithinta kuphela ikholoni. Ngokuphambene nalokho, iCrohn's ingathinta noma iyiphi ingxenye yepheshana lakho lesisu (GI).
Yiziphi izinkinga ze-UC engalashwa noma engaphathwa kahle?
Ukwelashwa okungafanele noma ukwelashwa okungalashwa kungadala izinhlungu zesisu, isifo sohudo, nokopha okunezikhala. Ukopha kakhulu kungadala ukukhathala okukhulu, i-anemia emakiwe, nokuphefumula okuncane. Uma i-UC yakho inzima kangangoba ayiphenduli ekwelashweni kwezokwelapha, udokotela angancoma ukuthi kususwe ikholoni yakho (eyaziwa nangokuthi amathumbu amakhulu).
Yiziphi izinketho zokwelashwa ezitholakalayo ze-UC? Ngabe zikhona ezinye ezisebenza kangcono kunezinye?
Unezinketho ezilandelayo zokwelashwa ze-UC:
Ama-anti-inflammatories
Le mithi imvamisa iyinkambo yokuqala yokwelapha i-UC. Kubandakanya ama-corticosteroids nama-5-aminosalicylates (5-ASAs). Ngokuya ngokuthi iyiphi ingxenye yekholoni ethintekile, ungathatha le mithi ngomlomo, njenge-suppository, noma njenge-enema.
Imithi elwa namagciwane
Odokotela banikeza ama-antibiotic uma besola ukuthi kukhona ukutheleleka kukholoni yakho. Kodwa-ke, abantu abane-UC bavame ukwelulekwa ukuthi bangathathi ama-antibiotic ngoba angadala uhudo.
Ama-immunosuppressors
Le mithi ingalawula ukuvuvukala. Kubandakanya i-mercaptopurine, i-azathioprine, ne-cyclosporine. Hlala uthintana nodokotela wakho uma uthatha lokhu. Imiphumela emibi ingathinta isibindi sakho kanye namanyikwe akho.
Izindlela zokwelapha ze-Biologic
Imithi yokwelapha ihlanganisa i-Humira (adalimumab), i-Remicade (infliximab), ne-Simponi (i-golimumab). Zaziwa nangokuthi i-tumor necrosis factor (TNF) inhibitors. Zilawula ukusabela kwakho komzimba okungajwayelekile. I-Entyvio (vedolizumab) isetshenziselwa ukwelashwa kwe-UC kubantu abangaphenduli noma abangakwazi ukubekezelela ezinye izindlela zokwelashwa ezahlukahlukene.
Ingabe kunemiphumela engemihle yemithi okufanele ngiyazi?
Okulandelayo uhlu lwezinye izidakamizwa ze-UC ezivamile ezinemiphumela yazo ejwayelekile:
Izidakamizwa ezilwa nokuvuvukala
Imiphumela emibi ejwayelekile yama-5-ASA ifaka ukuhlanza, isicanucanu, nokulahlekelwa isifiso sokudla.
Esikhathini eside, ama-corticosteroids angaholela emiphumeleni emibi efana nomfutho wegazi ophakeme, ingozi eyengeziwe yokutheleleka, amazinga aphezulu kashukela egazini, induna, ukukhuluphala, ukushintsha kwemizwelo, uketshezi lwamehlo, ukuqwasha namathambo angasebenzi kahle.
Imithi elwa namagciwane
UCipro noFlagyl bavame ukunikezwa abantu abane-UC. Imiphumela yabo ejwayelekile ifaka phakathi isisu esidabukisayo, isifo sohudo, ukungathandi ukudla nokuhlanza.
I-Cipro iyi-antibiotic ye-fluoroquinolone. Ama-fluoroquinolones angakhuphula ubungozi bezinyembezi ezinkulu noma ukuqhuma kwe-aorta, okungadala ukopha okungathi sína, okusongela ukuphila.
Abadala nabantu abanomlando wama-aneurysms noma izifo ezithile zenhliziyo bangaba sengozini enkulu. Lesi sehlakalo esingesihle singenzeka nganoma iyiphi i-fluoroquinolone ethathwe ngomlomo noma njengomjovo.
Ama-immunosuppressors
I-6-mercaptopurine (6-MP) ne-azathioprine (AZA) ingadala imiphumela emibi njengokuncipha kokumelana nokutheleleka, umdlavuza wesikhumba, ukuvuvukala kwesibindi, ne-lymphoma.
Izindlela zokwelapha ze-Biologic
Izindlela zokwelapha ze-Biologic zifaka i-Humira (adalimumab), i-Remicade (infliximab), i-Entyvio (vedolizumab), i-Certolizumab (i-Cimzia), ne-Simponi (i-golimumab).
Imiphumela emibi ejwayelekile ifaka ukulunywa, ububomvu, ubuhlungu noma ukuvuvukala okuncane eduze kwendawo yokujova, umkhuhlane, ikhanda elibuhlungu, amakhaza nokuqubuka.
Ngizokwazi kanjani uma ukwelashwa kwami kungasebenzi kahle?
Uma umuthi wakho ungasebenzi, uzothola uhudo oluqhubekayo, ukuphuma kwegazi, nobuhlungu besisu - noma ngemuva kwamasonto amathathu kuya kwamane okulo muthi.
Yiziphi izimbangela ezivamile ze-UC?
Izimbangela ezivamile ze-UC zifaka phakathi ubisi, ubhontshisi, ikhofi, imbewu, i-broccoli, ummbila notshwala.
Kuvame kangakanani i-UC? Ama-IBD? Ingabe kuwufuzo?
Ngokuya ngokulinganisa kwamanje, cishe bahlala ne-IBD. Uma unelungu lomndeni eline-IBD, kungakhuphula ubungozi bokulikhulisa.
- Ukusabalala kwe-UC kungama-238 kubo bonke abantu abadala abayi-100,000.
- Ukusabalala kweCrohn's cishe kungama-201 kubo bonke abantu abadala abayi-100,000.
Ingabe kukhona amakhambi emvelo e-UC? Ezinye izindlela zokwelapha? Ingabe ziyasebenza?
Kubantu abangakwazi ukubekezelela imithi, kunezinye izinketho ezimbalwa.
Amakhambi ezokudla
Ukudla okuphansi kwe-fiber namafutha kubonakala kuwusizo kakhulu ekwehliseni imvamisa ye-UC flare-ups ejwayelekile. Ukuqeda ukudla okuthile ekudleni kwakho kungaba nomphumela ofanayo. Isibonelo, ubisi, utshwala, inyama, nokudla okunama-carb amaningi.
Amakhambi esintu
Imithi ehlukahlukene yamakhambi ingakulungela ukwelashwa kwe-UC. Kubandakanya iBoswellia, imbewu ye-psyllium / ikhoba, ne-turmeric.
Ukuphathwa kwengcindezi
Ungavimbela ukubuyela emuva kwe-UC ngezindlela zokwelapha ezikhulula ukucindezeleka, njenge-yoga noma ukuzindla.
Ukuzivocavoca umzimba
Ukungeza umsebenzi ojwayelekile womzimba enkambisweni yakho kungasiza ukuphatha i-UC yakho.
Ingabe kufanele ngicabange ngokuhlinzwa?
Cishe amaphesenti angama-25 kuye kwangama-40 abantu abane-UC badinga ukuhlinzwa ukuze kususwe ikholoni.
Ukuhlinzwa kuyadingeka ngenxa yalokhu okulandelayo:
- ukwehluleka ukwelashwa
- ukopha kakhulu
- imiphumela emibi kakhulu yemithi ethile
Ungalutholaphi ulwazi oluthe xaxa nge-UC noma uthole ukwesekwa kubantu nabo abaphila nalesi simo?
Isisetshenziswa esingakholeki nesuselwa ebufakazini yiCrohn's and Colitis Foundation of America. Inhlangano engenzi nzuzo enamathani emininingwane ewusizo ekuphathweni kwe-UC.
Ungathola eminye imininingwane ngokujoyina imiphakathi eyahlukahlukene yezokuxhumana ye-UC. Uzozuza ngokuhlangana nokuxhumana nabanye abantu ababhekene nezinkinga ezifanayo ngqo.
Ungasiza futhi ukuxhasa ngokuhlela imihlangano, imicimbi, nemisebenzi. Lokhu kunikeza ithuba kubantu abathintwe yilesi sifo ukushintshana ngamathiphu, izindaba nezinsizakusebenza.
UDkt Saurabh Sethi ungudokotela oqinisekiswe ngamabhodi onguchwepheshe we-gastroenterology, hepatology, kanye ne-endoscopy yokungenelela esezingeni eliphakeme. Ngo-2014, uDkt. Sethi waqedela ubudlelwano bakhe be-gastroenterology kanye ne-hepatology eBeth Israel Deaconess Medical Center eHarvard Medical School. Ngokushesha ngemuva kwalokho, waqeda ubudlelwane bakhe obuphambili be-endoscopy eStanford University e2015. UDkt.Sethi ubambe iqhaza ezincwadini eziningi nasekushicilelweni kocwaningo, kufaka phakathi izincwadi ezingaphezu kuka-30 ezibuyekezwa ontanga. Izintshisekelo zikaDkt Sethi zifaka ukufunda, ukubhuloga, ukuhamba, kanye nokukhuthaza ezempilo zomphakathi.