Izinhlobo ze-Basal Insulin, Izinzuzo, Ulwazi Lwesilinganiso, Nemiphumela engemihle

-Delile

• Izinhlobo
• I-insulin esebenza phakathi, i-NPH
• I-insulin esebenza isikhathi eside
• I-insulin esebenza isikhathi eside
• Ukucatshangelwa
• Izinzuzo
• Imininingwane yesilinganiso
• Ukuthatha i-NPH ngesikhathi sokulala, ekuseni, noma kokubili
• Ukuthatha i-detemir, glargine, noma i-degludec ngesikhathi sokulala
• Usebenzisa ipompo ye-insulin
• Okuqhamuka uma udla imishanguzo
• Ngezansi

Umsebenzi oyinhloko we-basal insulin ukugcina amazinga eglucose egazi wakho azinzile ngezikhathi zokuzila, njengalapho ulele. Ngenkathi uzila ukudla, isibindi sakho ngokuqhubekayo sikhipha ushukela egazini. I-insulin eyisisekelo igcina la mazinga e-glucose elawula.

Ngaphandle kwale insulin, amazinga akho eglucose angakhuphuka ngezinga elishaqisayo. I-insulin eyisisekelo iqinisekisa ukuthi amaseli akho ondliwa ngomchamo ongaguquki we-glucose ukuze ushise amandla usuku lonke.

Nakhu okudingeka ukwazi ngemithi ye-basal insulin nokuthi kungani kubalulekile ukuphatha isifo sikashukela.

Izinhlobo

Kunezinhlobo ezintathu eziyinhloko ze-basal insulin.

I-insulin esebenza phakathi, i-NPH

Izinhlobo zamagama omkhiqizo zifaka iHumulin neNovolin. Le insulin iphathwa kanye noma kabili nsuku zonke. Imvamisa ixutshwe ne-insulin yesikhathi sokudla ekuseni, ngaphambi kokudla kwakho kwakusihlwa, noma kokubili. Isebenza kanzima kakhulu emahoreni ama-4 kuye kwayi-8 ngemuva kokujova, futhi imiphumela iqala ukuncipha ngemuva kwamahora angaba ngu-16.

I-insulin esebenza isikhathi eside

Izinhlobo ezimbili zale insulin okwamanje emakethe yi-detemir (Levemir) ne-glargine (Toujeo, Lantus, neBasaglar). Le insulin eyisisekelo iqala ukusebenza imizuzu engama-90 kuya emahoreni amane ngemuva kokujova futhi ihlala egazini lakho kuze kube ngamahora angama-24. Kungase kuqale ukwehlisa amandla amahora ambalwa ngaphambili kwabanye abantu noma kudlule amahora ambalwa isikhathi eside kwabanye. Asikho isikhathi esiphakeme salolu hlobo lwe-insulin. Isebenza ngezinga elizinzile usuku lonke.

I-insulin esebenza isikhathi eside

NgoJanuwari 2016, kukhishwe enye i-insulin eyisisekelo ebizwa nge-degludec (Tresiba). Le insulin eyisisekelo iqala ukusebenza kungakapheli imizuzu engama-30 kuya kwengu-90 futhi ihlala egazini lakho kuze kube ngamahora angama-42. Njengakwi-insulins esebenza isikhathi eside i-detemir ne-glargine, asikho isikhathi esiphakeme sale insulin. Isebenza ngezinga elizinzile usuku lonke.

I-insulin degludec itholakala ngamandla amabili, i-100 U / mL ne-200 U / mL, ngakho-ke kufanele uqiniseke ukuthi ufunda ilebula bese ulandela imiyalelo ngokucophelela. Ngokungafani ne-detemir ne-glargine, ingaxubaniswa nenye i-insulin esebenza ngokushesha engafika emakethe kungekudala.

Ukucatshangelwa

Lapho uthatha isinqumo phakathi kwama-basal insulin aphakathi nendawo nalawo asebenza isikhathi eside, kunezinto eziningi okufanele uzicabangele. Lokhu kufaka phakathi indlela ophila ngayo nokuzimisela ukujova.

Isibonelo, ungaxuba i-NPH ne-insulin yesikhathi sokudla, kuyilapho i-insulin eyisisekelo esebenza isikhathi eside kumele ijovwe ngokwahlukana. Izici ezingathinta isilinganiso sakho se-insulin zifaka usayizi womzimba wakho, amazinga ama-hormone, indlela odla ngayo, nokuthi ingxenyeni yangaphakathi ama-pancreas asakhipha malini, uma ikhona.

Izinzuzo

Abantu abaningi abanesifo sikashukela bathanda i-basal insulin ngoba ibasiza ukuphatha kangcono amazinga kashukela egazini phakathi kokudla, futhi ivumela indlela yokuphila eguquguqukayo.

Isibonelo, uma usebenzisa i-insulin esebenza isikhathi eside, awudingi ukukhathazeka ngezikhathi eziphakeme zomsebenzi we-insulin. Lokhu kusho ukuthi isikhathi sokudla singashintshashintsha. Kunganciphisa ubungozi bamazinga kashukela asezingeni eliphansi.

Uma ulwela ukugcina amazinga kashukela egazini lakho ekuseni, ukufaka i-basal insulin esikhathini sakho sokudla noma isikhathi sokulala kungasiza ukuxazulula le nkinga.

Imininingwane yesilinganiso

Nge-basal insulin, unezinketho ezintathu zomthamo. Inketho ngayinye inobuhle nobubi. Izidingo ze-basal insulin zawo wonke umuntu zihlukile, ngakho-ke udokotela wakho noma i-endocrinologist angakusiza ukuthi unqume ukuthi imuphi umthamo olungele wena.

Ukuthatha i-NPH ngesikhathi sokulala, ekuseni, noma kokubili

Le ndlela ingaba usizo ngoba i-insulin iyanda ngesikhathi sangaphambi nantambama, lapho idingeka kakhulu. Kepha lokho kuphakama kungalindeleka ngokuya ngokudla kwakho, isikhathi sokudla, nezinga lomsebenzi. Lokhu kungaholela emazingeni kashukela asezingeni eliphansi ngenkathi ulele noma amazinga we-glucose egazi aphansi noma aphezulu ngesikhathi sasemini.

Ukuthatha i-detemir, glargine, noma i-degludec ngesikhathi sokulala

Ukugeleza okuqhubekayo kwalezi insulins ezisebenza isikhathi eside kungenye yezinzuzo zazo ezinkulu. Kepha, abanye abantu bathola ukuthi i-detemir ne-glargine insulin iphela ngokushesha kunamahora angama-24 ngemuva kokujova. Lokhu kungasho amazinga aphezulu eglucose egazini kumjovo wakho olandelayo ohleliwe. I-Degludec kufanele ihlale kuze kufike umjovo wakho ohleliwe olandelayo.

Usebenzisa ipompo ye-insulin

Ngephampu ye-insulin, ungaguqula isilinganiso se-basal insulin ukuze ihambisane nokusebenza kwesibindi sakho. Okunye ukubuyela emuva ekwelapheni ukupompa ubungozi be-ketoacidosis yesifo sikashukela ngenxa yokupompa ukungasebenzi kahle. Noma iyiphi inkinga yomshini ngepompo ingaholela ekutheni ungatholi inani elifanele le-insulin.

Okuqhamuka uma udla imishanguzo

Eminye imiphumela emibi engaba khona ehlotshaniswa ne-basal insulin ifaka i-hypoglycemia nokutholakala kwesisindo okungenzeka, yize kungaphansi kancane uma kuqhathaniswa nezinye izinhlobo ze-insulin.

Izidakamizwa ezithile, kufaka phakathi i-beta-blockers, i-diuretics, i-clonidine, ne-lithium usawoti, zinganciphisa imiphumela ye-basal insulin. Khuluma nodokotela wakho kanye ne-endocrinologist mayelana nemithi oyiphuzayo njengamanje kanye nanoma yikuphi ukuhlangana kwezidakamizwa okuyingozi.

Ngezansi

I-insulin eyisisekelo iyinto ebalulekile ekuphathweni kwesifo sikashukela. Sebenza nodokotela wakho noma i-endocrinologist ukuthola ukuthi yiluphi uhlobo olulungele wena nezidingo zakho.