Ama-Probiotic wohudo: Izinzuzo, Izinhlobo, Nemiphumela emibi

-Delile

• Ama-probiotic angaselapha kanjani futhi asivimbele kanjani isifo sohudo
• Izinhlobo zohudo eziphendula ekwelashweni kwama-probiotic
• Isifo sohudo esithathelwanayo
• Uhudo oluhambisana namagciwane
• Uhudo lomhambi
• Uhudo oluthinta izingane nezinsana
• Izinhlobo ezinhle kakhulu zama-probiotic okwelapha isifo sohudo
• Imiphumela emibi engaba khona ehlobene nokusetshenziswa kwama-probiotic
• Okubalulekile

Sifaka imikhiqizo esicabanga ukuthi ilusizo kubafundi bethu. Uma uthenga ngezixhumanisi ezikuleli khasi, singathola ikhomishini encane. Nansi inqubo yethu.

Ama-Probiotic angamagciwane asizayo akhonjisiwe anikezela ngezinzuzo eziningi zezempilo.

Kanjalo, izithasiselo ze-probiotic kanye nokudla okune-probiotic sekuyizindlela zokwelashwa ezidumile zezimo eziningi zezempilo, kufaka phakathi izingqinamba zokugaya ukudla ezifana nohudo ().

Lo mbhalo uchaza ukuthi ama-probiotic angasiza kanjani ekulweni nohudo, ukubuyekezwa okuyizinkinga ezisebenza kakhulu, futhi kubhekane nemiphumela engemihle ehambisana nokusetshenziswa kwama-probiotic.

Ama-probiotic angaselapha kanjani futhi asivimbele kanjani isifo sohudo

Ngaphezu kokutholakala kwizithasiselo nokudla okuthile, ama-probiotic ngokwemvelo ahlala emathunjini akho. Lapho badlala izindima eziningi ezibalulekile, njengokugcina impilo yomzimba nokuvikela umzimba wakho ekuthelelekeni nasezifweni ().

Ama-bacteria asemathunjini akho - ngokuhlanganyela aziwa ngokuthi yi-gut microbiota - angathinteka kabi futhi anokuthinteka kahle ezintweni ezahlukahlukene, kufaka phakathi ukudla, ingcindezi, nokusetshenziswa kwemithi.

Lapho ukwakheka kwamagciwane kungalingani futhi inani elijwayelekile lama-probiotic laphazamiseka, kungaholela emiphumeleni emibi yezempilo, njengengozi eyengeziwe yezimo ezinjenge-irritable bowel syndrome (IBS) kanye nezimpawu zokugaya ukudla ezifana nohudo (,).

I-World Health Organisation ichaza isifo sohudo ngokuthi "sinendle ezintathu noma ngaphezulu ezivulekile noma ezinamanzi esikhathini samahora angama-24." Uhudo olunamandla luhlala ngaphansi kwezinsuku eziyi-14 ngenkathi uhudo oluqhubekayo luthatha izinsuku eziyi-14 noma ngaphezulu ().

Ukwengeza ngama-probiotic kungasiza ekuvikeleni izinhlobo ezithile zohudo futhi kusize ekwelapheni isifo sohudo ngokuphindaphinda futhi nokugcina ama-bacteria asebenzayo nokulungisa ukungalingani.

Ama-Probiotic alwa nama-bacterium e-pathogenic ngokuncintisana nezakhi zomzimba, ukukhulisa amasosha omzimba, nokuguqula imvelo yamathumbu ukuyenza ingahambelani nomsebenzi we-pathogenic ().

Eqinisweni, ucwaningo lukhombisile ukuthi ama-probiotic supplements avimbela futhi aphathe izinhlobo ezithile zohudo ezinganeni nakubantu abadala.

Ukuthatha ama-probiotic kungasiza ekuvikeleni nasekwelapheni isifo sohudo ngokuphindaphinda ama-bacterium anenzuzo emathunjini nokulungisa ukungalingani emzimbeni we-gut microbiota.

Izinhlobo zohudo eziphendula ekwelashweni kwama-probiotic

Uhudo lunezimbangela eziningi ezahlukahlukene, kufaka phakathi ukutheleleka ngamagciwane noma igciwane, imishanguzo ethile, kanye nokuchayeka kumagciwane ahlukahlukene ohambweni.

Ucwaningo lukhombisile ukuthi izinhlobo eziningi zohudo zisabela kahle kuma-probiotic supplements.

Isifo sohudo esithathelwanayo

Isifo sohudo esithathelwanayo isifo sohudo esibangelwa i-agent ethathelwanayo, njengama-bacteria noma ama-parasites. Ama-bacteria angaphezu kwama-20 ahlukene, amagciwane, kanye nezimuncagazi kuyaziwa ukuthi kubanga isifo sohudo esithathelwanayo, kufaka phakathi I-Rotavirus, E. coli, futhi Salmonella ().

Uhudo oluthathelwanayo luvame kakhulu emazweni asathuthuka futhi lungaholela ekufeni uma lungalashwa. Ukwelashwa kubandakanya ukuvimbela ukuphelelwa amandla kwamanzi, ukunciphisa isikhathi umuntu atheleleka ngaso, nokunciphisa isikhathi sohudo.

Ukubuyekezwa okukodwa kwezifundo ezingama-63 kubantu abayi-8,014 kuphethe ngokuthi ama-probiotic anciphise ngokuphepha isikhathi sohudo kanye nokuvama kwesitulo kubantu abadala nasezinganeni ezinesifo sohudo esithathelwanayo ().

Ngokwesilinganiso, amaqembu aphathwa ngama-probiotic ahlangabezana nohudo cishe amahora angama-25 ngaphansi kwamaqembu wokulawula ().

Uhudo oluhambisana namagciwane

Ama-antibiotic yimithi esetshenziselwa ukwelapha ukugula okuningana okubangelwa amagciwane. Isifo sohudo siwumphumela ojwayelekile wokwelashwa kwama-antibiotic ngenxa yokuphazanyiswa kwe-gut microbiota ejwayelekile le mithi eyibangelayo.

Ukuthatha ama-probiotic kungasiza ekuvikeleni isifo sohudo esihambisana nokusetshenziswa kwama-antibiotic ngokuphindaphinda amabhaktheriya alusizo emathunjini.

Ukubuyekezwa kwezifundo eziyi-17 kubantu abangu-3,631 kukhombisile ukuthi isifo sohudo esihambisana nemithi elwa namagciwane besisabalele kakhulu kulabo abebengezelela ngama-probiotic.

Eqinisweni, cishe abantu abangu-18% emaqenjini okulawula babenesifo sohudo esihambisana nama-antibiotic ngenkathi kuphela i-8% yabantu abaseqenjini abaphathwa ngama-probiotic abathintekile ().

Ukubuyekezwa kuphethe ngokuthi ama-probiotic - ikakhulukazi I-Lactobacillus rhamnosus GG futhi ISaccharomyces boulardii izinhlobo- zinganciphisa ubungozi bohudo obuhambisana nama-antibiotic ngama-51% ().

Uhudo lomhambi

Ukuhamba kukuvezela izinhlobo eziningi zama-microorganism ezingavamisile ukwethulwa ohlelweni lwakho, ezingadala uhudo.

Uhudo lomhambi luchazwa ngokuthi "ukudlula kwezitulo ezintathu noma ngaphezulu ezingafakwanga ngosuku" okungenani ezinophawu olulodwa oluhlobene, njengezikhwebu noma izinhlungu zesisu, ezenzeka kumhambi ngemuva kokufika lapho eya khona. Ithinta abantu abayizigidi ezingama-20 minyaka yonke (,).

Ukubuyekezwa kwezifundo eziyi-11 kuthole ukuthi ukwelashwa kokuvimbela izithasiselo ze-probiotic kunciphise kakhulu ukuvela kohudo ().

Okunye ukubuyekezwa kwe-2019 kwezifundo ze-12 kukhombisile ukuthi ukwelashwa kuphela nge-probiotic ISaccharomyces boulardii kuholele ekwehliseni okukhulu okufika ku-21% kuhudo lwabahambi ().

Uhudo oluthinta izingane nezinsana

Isifo sohudo esihambisana namagciwane nezifo ezibangela isifo sohudo kuvame kakhulu ezinganeni nasezinganeni.

I-Necrotizing enterocolitis (NEC) yisifo samathumbu esenzeka cishe kuphela ezinganeni. Lesi sifo sibonakala ngokuvuvukala kwamathumbu okuholela ekwandeni kwamagciwane, okulimaza kakhulu amaseli amathumbu nekholoni ().

I-NEC yisimo esibi kakhulu esinezinga lokushona elifinyelela kuma-50% ().

Esinye sezimpawu ze-NEC yisifo sohudo esibi. Imithi elwa namagciwane ivame ukusetshenziselwa ukwelapha lesi sifo, okungaholela kuhudo oluhambisana nama-antibiotic olungasenza sibe sibi isimo sesiguli.

Ngokwengeziwe, abanye ochwepheshe basikisela ukuthi ukwelashwa ngama-antibiotic kungaba yinto eyodwa ebangela i-NEC ().

Ucwaningo lukhombisile ukuthi ama-probiotic angasiza ekunciphiseni ubungozi be-NEC nokufa ezinganeni ezizalwe ngaphambi kwesikhathi ().

Ukubuyekezwa kwezifundo ezingama-42 ezibandakanya izinsana ezingaphezu kwezingu-5 000 ezingaphansi kwamasonto angama-37 ubudala kutholakale ukuthi ukusetshenziswa kwama-probiotic kwehlise izehlakalo ze-NEC futhi kwaveza ukuthi ukwelashwa kwama-probiotic kuholele ekwehleni kokufa kwezinsana ().

Ngokwengeziwe, okunye ukubuyekezwa kuphethe ngokuthi ukwelashwa kwama-probiotic kuhlotshaniswa namazinga aphansi ohudo oluhambisana nemithi elwa namagciwane ezinganeni ezineminyaka eyi-1 kuya eminyakeni eyi-18 ().

Olunye ucwaningo luthole ukuthi izinhlobo ezithile zama-probiotic, kufaka phakathi I-Lactobacillus rhamnosus I-GG, ingaphatha isifo sohudo esithathelanayo nasezinganeni ().

Ukuthatha ama-probiotic kungasiza ukuvimbela nokwelapha isifo sohudo esihambisana nokutheleleka, ukuhamba nokusetshenziswa kwama-antibiotic.

Izinhlobo ezinhle kakhulu zama-probiotic okwelapha isifo sohudo

Kunezinhlobo zamakhulu zama-probiotic, kepha ucwaningo lukhombisa ukuthi ukwengeza ngezimbalwa ezikhethiwe kusiza kakhulu uma ulwa nohudo.

Ngokuya ngokutholwe yisayensi kwakamuva, lezi zinhlobo ezilandelayo yizinhlobo ze-probiotic eziphumelela kakhulu zokwelapha isifo sohudo:

• I-Lactobacillus rhamnosus I-GG (LGG): Le probiotic iphakathi kwezinhlobo ezivame ukwengezwa. Ucwaningo lukhombisa ukuthi i-LGG ingenye yama-probiotic aphumelela kakhulu ekwelapheni isifo sohudo kubantu abadala nasezinganeni (,).
• ISaccharomyces boulardii:S. boulardii uhlobo olulusizo lwemvubelo olusetshenziswa kakhulu kuma-probiotic supplements. Kukhonjisiwe ukwelapha isifo sohudo esihambisana namagciwane nesifo esithathelwanayo (,).
• I-Bifidobacterium lactis: Le probiotic inezimfanelo zokuqinisa amasosha omzimba nezokuvikela amathumbu futhi ingahle inciphise kakhulu ukuqina nokuvama kwesifo sohudo ezinganeni ().
• I-Lactobacillus casei:L. icalai kungenye inkinga yama-probiotic eye yafundelwa izinzuzo zayo zokulwa nohudo. Olunye ucwaningo luphakamisa ukuthi welapha isifo sohudo esihambisana namagciwane nesifo esithathelwanayo ezinganeni nakubantu abadala (,).

Yize ezinye izinhlobo zama-probiotic zingasiza ekwelapheni isifo sohudo, izingqinamba ezibalwe ngenhla zinocwaningo oluningi olusekela ukusetshenziswa kwazo kwalesi simo esithile.

Ama-Probiotic alinganiswa kumaColony Forming Units (CFU), akhombisa inani lamagciwane azuzisayo agxile kudosi ngayinye. Izithasiselo eziningi ze-probiotic ziqukethe phakathi kwe-1 ne-10 billion CFU ngomthamo ngamunye.

Kodwa-ke, amanye ama-suppiotic supplements agcwele ama-CFU angaphezu kwezigidigidi eziyikhulu ngomthamo ngamunye.

Ngenkathi ukhetha isengezo se-probiotic esine-CFU ephezulu kubalulekile, izingqinamba ezifakwe kwisengezo nekhwalithi yomkhiqizo zibaluleke ngokulinganayo ().

Njengoba kunikezwe ukuthi ikhwalithi kanye ne-CFU yezithasiselo ze-probiotic zingahluka kakhulu, kungumbono omuhle ukusebenza nochwepheshe oqeqeshiwe wezokunakekelwa kwempilo ukukhetha ama-probiotic kanye nomthamo osebenza kahle kakhulu.

I-Lactobacillus rhamnosus GG, ISaccharomyces boulardii, iBifidobacterium lactis, futhi I-Lactobacillus casei ezinye zezinhlobo ezisebenza kahle kakhulu zama-probiotic ekwelapheni isifo sohudo.

Imiphumela emibi engaba khona ehlobene nokusetshenziswa kwama-probiotic

Ngenkathi ama-probiotic ngokuvamile abhekwa ephephile ezinganeni nakubantu abadala kanye nemiphumela emibi emibi engandile kubantu abaphilile, eminye imiphumela emibi engaba khona ingavela kubantu abathile.

Abantu abasengozini yokutheleleka, kufaka phakathi abantu abalulama lapho behlinzwa, izinsana ezigula kakhulu, nalabo abanamakhethini ahlala ngaphakathi noma abagula kakhulu basengozini yokuthola ukusabela okungekuhle ngemuva kokuthatha ama-probiotic ().

Isibonelo, ama-probiotic angadala ukutheleleka okunamandla kwesifo sohudo, ukukhuthaza amasosha omzimba okweqile, ukukhukhumala kwesisu, kanye nesicanucanu kubantu abangenalo ikhompiyutha ().

Imiphumela engemihle emincane ehlobene nokuthatha ama-probiotic kungenzeka ngezikhathi ezithile kubantu abaphilile, kufaka phakathi ukuqunjelwa, igesi, ama-hiccups, ukuqubuka kwesikhumba, nokuqunjelwa ().

Ngenkathi ama-probiotic ngokuvamile abhekwa njengaphephile kubantu abaningi, ngaso sonke isikhathi kuwumqondo omuhle ukubonisana nomhlinzeki wakho wezokunakekelwa kwempilo ngaphambi kokungeza noma isiphi isengezo kuwe noma ekudleni kwengane yakho.

Ama-Probiotic athathwa kabanzi njengaphephile kepha angadala imiphumela emibi kakhulu kubantu abangenakuqedwa.

Okubalulekile

Ngokusho kocwaningo lwakamuva, izinhlobo ezithile zama-probiotic zingasiza ekwelapheni nasekuvimbeleni izinhlobo ezahlukahlukene zohudo, kufaka phakathi isifo sohudo esihambisana nama-antibiotic, esithathelwanayo nesokuhamba.

Yize kunamakhulu ezinhlobo zama-probiotic atholakala kwifomu lokungezelela, bambalwa kuphela abafakazelwe ukuthi belapha isifo sohudo, kufaka phakathi I-Lactobacillus rhamnosus GG, ISaccharomyces boulardii, iBifidobacterium lactis, futhi I-Lactobacillus casei.

Uma unentshisekelo yokusebenzisa ama-probiotic ukwelapha noma ukuvimbela isifo sohudo, thintana nomhlinzeki wakho wezokunakekelwa kwezempilo ukuthola izeluleko.

Ungathenga izithasiselo ze-probiotic endaweni yangakini noma ku-inthanethi. Qiniseka ukuthi useshela izingcindezi umhlinzeki wakho wezokwelapha azincomayo.