Ukuhlolwa kwe-CCP Antibody

-Delile

• Kuyini ukuhlolwa kwe-antibody yeCCP?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-antibody yeCCP?
• Kwenzekani ngesikhathi sokuhlolwa kwamasosha omzimba e-CCP?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwamasosha omzimba kweCCP?
• Izinkomba

Kuyini ukuhlolwa kwe-antibody yeCCP?

Lokhu kuhlolwa kubheka ama-antibody eCCP (cyclic citrullinated peptide) egazini. Ama-antibody e-CCP, abizwa nangokuthi ama-anti-CCP antibodies, awuhlobo lomzimba omzimba obizwa ngokuthi ama-autoantibodies. Ama-antibody nama-autoantibodies amaprotheni enziwe amasosha omzimba. Ama-antibody akuvikela ezifweni ngokulwa nezinto zangaphandle njengamagciwane namagciwane. Ama-autoantibodies angadala izifo ngokuhlasela amaseli omzimba anempilo ngephutha.

Amasosha omzimba eCCP akhomba izicubu ezinempilo emajoyintini. Uma ama-antibody e-CCP etholakala egazini lakho, kungaba uphawu lwe-rheumatoid arthritis. I-rheumatoid arthritis isifo esiqhubekayo, esizimele esibangela ubuhlungu, ukuvuvukala nokuqina kwamalunga. Ama-antibody eCCP atholakala kumaphesenti angaphezu kwama-75 abantu abane-arthritis ye-rheumatoid. Cishe azitholakali kubantu abangenaso lesi sifo.

Amanye amagama: I-cyclic citrullinated peptide antibody, i-antitrullinated peptide antibody, i-citrulline antibody, i-anti-cyclic citrullinated peptide, anti-CCP antibody, i-ACPA

Kusetshenziselwa ini?

Isivivinyo samasosha omzimba seCCP sisetshenziselwa ukusiza ukuxilonga isifo samathambo. Kuvame ukwenziwa kanye noma ngemuva kokuhlolwa kwe-rheumatoid factor (RF). Izici ze-rheumatoid zingenye uhlobo lwe-autoantibody. Ukuhlolwa kwe-RF kwakuvame ukuba yisivivinyo esikhulu sokusiza ukuthola isifo samathambo. Kepha izinto ze-RF zingatholakala kubantu abanezinye izifo ezizimele ngisho nakwabanye abantu abaphilile. Ucwaningo oluningi lukhombisile ukuthi amasosha omzimba e-CCP ahlinzeka ngokuxilongwa okunembile kwesifo samathambo uma kuqhathaniswa nokuhlolwa kwe-RF.

Kungani ngidinga ukuhlolwa kwe-antibody yeCCP?

Ungadinga lokhu kuhlolwa uma unezimpawu zesifo samathambo. Lokhu kufaka phakathi:

• Ubuhlungu obuhlangene
• Ukuqina okuhlangene, ikakhulukazi ekuseni
• Ukuvuvukala okuhlangene
• Ukukhathala
• Umkhuhlane osezingeni eliphansi

Ungase futhi udinge lokhu kuhlolwa uma ezinye izivivinyo zingakwazanga ukuqinisekisa noma ukukhiphela ngaphandle ukuxilongwa kwesifo samathambo.

Kwenzekani ngesikhathi sokuhlolwa kwamasosha omzimba e-CCP?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Qiniseka ukuthi utshela umhlinzeki wakho wezokunakekelwa kwempilo ngayo yonke imithi, amavithamini, nezithako zokudla ozithathayo. Kungase kudingeke ukuthi uyeke ukuthatha izinto ezithile amahora angu-8 ngaphambi kokuhlolwa kwakho.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela ye-antibody yakho yeCCP ibithi iyakhanya, kusho ukuthi la ma-antibody atholakala egazini lakho. Umphumela ongemuhle usho ukuthi awekho ama-antibody e-CCP atholakele. Incazelo yale miphumela ingaxhomeka emiphumeleni yokuhlolwa kwe-rheumatoid factor (RF) kanye nokuhlolwa komzimba.

Uma unezimpawu zesifo samathambo, futhi imiphumela yakho ikhombisa:

• Ama-antibody e-CCP amahle ne-RF enhle, kungenzeka ukuthi kusho ukuthi une-arthritis ye-rheumatoid.
• Ama-antibody e-CCP amahle ne-RF engeyinhle, kungasho ukuthi usezigabeni zokuqala zesifo samathambo noma uzoyithuthukisa ngokuzayo.
• Ama-antibody e-CCP ama-Negative ne-RF engeyinhle, kusho ukuthi mancane amathuba okuthi ube nesifo samathambo. Umhlinzeki wakho angadinga ukwenza izivivinyo eziningi ukusiza ukuthola ukuthi yini ebangela izimpawu zakho.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwamasosha omzimba kweCCP?

I-rheumatoid arthritis ingaba nzima ukuyithola, ikakhulukazi lapho isanda kuqala. Umhlinzeki wakho anga-oda ukuhlolwa okukodwa noma okuningi ngaphezu kwe-CCP antibody ne-RF. Lokhu kufaka ama-x-ray amajoyinti akho kanye nokuhlolwa kwegazi okulandelayo:

• Izinga le-sedimentation ye-Erythrocyte (ESR)
• Ukuhlaziywa kwe-Synovial fluid
• Amaprotheni asebenza ngo-C
• I-antibody ye-Antinuclear

Lokhu kuhlolwa kwegazi kungakhombisa izimpawu zokuvuvukala. Ukuvuvukala uhlobo lokuphendula kwamasosha omzimba. Kungaba uphawu lwesifo samathambo.

Izinkomba

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Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.