Konke Okufanele Ukwazi Nge-Cholestasis

-Delile

• Izimpawu
• Izimbangela ze-cholestasis
• Imithi
• Izifo
• I-cholestasis yokukhulelwa
• Izimbangela nezici zobungozi
• Ukuxilongwa
• Ukwelashwa
• Umbono

Yini i-cholestasis?

I-cholestasis yisifo sesibindi. Kwenzeka lapho ukugeleza kwenyongo esibindini sakho kuncishisiwe noma kuvinjelwe. Inyongo inguketshezi olukhiqizwa isibindi sakho esisiza ekugayweni kokudla, ikakhulukazi amafutha. Lapho ukugeleza kwe-bile kuguqulwa, kungaholela ekwakhiweni kwe-bilirubin. I-Bilirubin i-pigment ekhiqizwa isibindi sakho futhi ikhishwe emzimbeni wakho nge-bile.

Kunezinhlobo ezimbili ze-cholestasis: i-intrahepatic cholestasis ne-extrahepatic cholestasis. I-Intrahepatic cholestasis ivela ngaphakathi kwesibindi. Kungabangelwa:

• isifo
• ukutheleleka
• ukusetshenziswa kwezidakamizwa
• ukungajwayelekile kofuzo
• imiphumela ye-hormonal ekugelezeni kwe-bile

Ukukhulelwa nakho kungakhuphula ubungozi bakho kulesi simo.

I-Extrahepatic cholestasis ibangelwa yisithiyo ngokomzimba emibhobho yenyongo. Ukuvinjelwa okuvela ezintweni ezinjenge-gallstones, ama-cysts, kanye nezicubu kuvimbela ukuhamba kwe-bile.

Funda kabanzi ukuze ufunde kabanzi ngalesi simo.

Izimpawu

Zombili lezi zinhlobo ze-cholestasis zibangela izimpawu ezifanayo:

• i-jaundice, okuphuzi kwesikhumba sakho nokumhlophe kwamehlo akho
• umchamo omnyama
• isitulo esinombala okhanyayo
• ubuhlungu esiswini sakho
• ukukhathala
• isicanucanu
• ukulunywa ngokweqile

Akuwona wonke umuntu one-cholestasis onezimpawu, nabantu abadala abane-cholestasis engapheli abangenazimpawu.

Izimbangela ze-cholestasis

Ukuvinjelwa kwe-bile kungadalwa yizinto eziningi.

Imithi

Isibindi sakho sidlala indima ebalulekile ekusetshenzisweni kwemithi. Eminye imishanguzo inzima kakhulu ukuthi isibindi sakho sigayeze ezinye kunaleyo enobuthi esibindini sakho. Le mithi ihlanganisa:

• amanye ama-antibiotic, njenge-amoxicillin (Amoxil, Moxatag) ne-minocycline (Minocin)
• ama-anabolic steroids
• amanye ama-anti-inflammatories ama-nonsteroidal (ama-NSAID), njenge-ibuprofen (Advil, Motrin IB)
• izinto zokuvimbela inzalo ngomlomo
• izidakamizwa ezithile zokulwa nesifo sokuwa
• izidakamizwa ezithile ezibulala ukhunta
• ezinye izidakamizwa zokulwa nengqondo
• imithi ethile elwa namagciwane

Kufanele njalo uthathe imishanguzo njengokuyalelwa, futhi ungayeki ukuthatha imishanguzo udokotela wakho akubekile ngaphandle kokukhuluma nabo kuqala.

Izifo

Izifo ezithile zibangela izibazi noma ukuvuvukala emathangeni e-bile, okuholela ku-cholestasis. Izimo zifaka:

• ukutheleleka okuvela kumagciwane afana ne-HIV, hepatitis, cytomegalovirus, ne-Epstein-Barr
• izifo ezibangelwa amagciwane
• izifo ezithile ezizimele, njenge-cirrhosis eyinhloko ye-biliary, engadala ukuthi amasosha omzimba wakho ahlasele futhi alimaze imiphongolo ye-bile
• ukuphazamiseka kofuzo, njengesifo se-sickle cell
• ezinye izinhlobo zomdlavuza, njengomdlavuza wesibindi nowe-pancreatic, kanye nama-lymphomas

I-cholestasis yokukhulelwa

I-Intrahepatic cholestasis yokukhulelwa, ebizwa nangokuthi i-obstetric cholestasis, kulinganiselwa ukuthi yenzeke ekukhulelweni okungu-1 kuye kwezi-2 kwabangu-1 000 e-United States. Uphawu oluvame kakhulu lwe-cholestasis yokubelethisa ukulunywa ngaphandle kokuqubuka. Lokhu kudalwa ukwakheka kwama-bile acid egazini.

Ukulunywa ngokuvamile kwenzeka ku-trimester yokugcina yokukhulelwa. Kungabuye kuhambisane nalokhu:

• i-jaundice
• indle ephaphathekile
• umchamo omnyama
• ubuhlungu besisu
• isicanucanu

Bheka udokotela wakho uma ulunywa lapho ukhulelwe. Eminye imishanguzo yamakhasimende, efana nama-antihistamine noma ama-anti-itch cream aqukethe i-cortisone, ngokuvamile ayisebenzi ekwelapheni lesi simo futhi ingalimaza ingane yakho engakazalwa. Esikhundleni salokho, udokotela wakho angakunika imishanguzo esiza ngokulunywa kodwa ngeke ilimaze ingane yakho.

Izimbangela nezici zobungozi

I-cholestasis eyenzeka ngesikhathi sokukhulelwa ingaba isimo esizuzwe njengefa. Uma umama noma udadewenu abenalesi simo ngesikhathi sokukhulelwa, ungaba nengozi eyengeziwe yokuthola futhi i-cholestasis yokubelethisa.

Ama-hormone okukhulelwa nawo angadala lesi simo. Lokho kungenxa yokuthi zingathinta ukusebenza kwakho kwe-gallbladder, okuvumela i-bile ukuba yakhe futhi igeleze iye egazini lakho.

Abesifazane abaphethe okuphindaphindwayo basengozini enkulu yokuthola i-cholestasis yokubelethisa.

Ukuxilongwa

Udokotela wakho uzokubuza imibuzo ngomlando wakho wezokwelapha. Uzophinde ube nokuhlolwa ngokomzimba. Ukuhlolwa kwegazi kungalawulwa ukuthi kuhlolwe ama-enzyme wesibindi akhombisa i-cholestasis. Uma imiphumela yokuhlolwa ingavamile, udokotela wakho angalawula ukuhlolwa kwe-imaging njenge-ultrasound noma i-MRI. Udokotela wakho angenza futhi i-biopsy yesibindi.

Ukwelashwa

Isinyathelo sokuqala sokwelapha i-cholestasis ukuphatha imbangela eyisisekelo. Isibonelo, uma kunqunywa ukuthi umuthi ubangela isimo, udokotela wakho angancoma umuthi ohlukile. Uma ukuvinjelwa okunjengamatshe enyongo noma isimila kubangela ukulondolozwa kwe-bile, udokotela wakho angancoma ukuhlinzwa.

Ezimweni eziningi, i-cholestasis ebelethayo ixazululwa ngemuva kokubeletha. Abesifazane abahlakulela i-cholestasis yokubeletha kufanele babhekwe ngemuva kokukhulelwa.

Umbono

I-cholestasis ingenzeka nganoma yisiphi isikhathi, futhi kubo bobabili abesilisa nabesifazane. Ukubuyiselwa esimweni kuncike ekutheni leli cala lalinzima kangakanani ngaphambi kokuba litholwe kuqala. Esinye isici imbangela eyinhloko yalesi sifo nokuthi singaphathwa kahle kanjani. Isibonelo, ama-gallstones angasuswa, aphulukisa lesi sifo. Uma isimo sidalwa ukulimala kwesibindi sakho, ukululama kungaba nzima kakhulu.

Ungenza izinto ezimbalwa ukunciphisa ubungozi be-cholestasis:

• Gomela i-hepatitis.
• Ungasebenzisi kabi utshwala.
• Gwema ukusebenzisa izidakamizwa ezifaka emithanjeni yokuzilibazisa.

Bheka udokotela wakho ngokushesha uma usola i-cholestasis. Ukwelashwa ngaphambi kwesikhathi kungathuthukisa amathuba akho okululama ngokugcwele.