Amanani okusinda kanye ne-Outlook ye-Chronic Lymphocytic Leukemia

-Delile

• Izinga lokusinda leukemia engapheliyo ye-lymphocytic
• Izici ezinomthelela ekubukeni kwe-lymphocytic leukemia engapheli
• Ngabe sesiseduze nokwelashwa?
• Ukubhekana nokusekelwa kwe-leukemia engapheli ye-lymphocytic
• Veza imizwa yakho
• Zifundise
• Khuthala
• Susa ingqondo yakho esifo sakho

I-leukemia engapheli ye-lymphocytic

I-chronic lymphocytic leukemia (CLL) wuhlobo lomdlavuza oluthinta igazi nomnkantsha wethambo. Umnkantsha wethambo yinto ethambile, enesiponji ngaphakathi kwamathambo akhiqiza amangqamuzana egazi. I-CLL ingumphumela wezinguquko ezahlukahlukene zofuzo kwi-DNA yamaseli akhiqiza igazi. Imbangela ngqo yalezi zinguquko ayaziwa. Lezi zinguquko ze-DNA zenzeka phakathi nesikhathi sokuphila, kunokuba zifane nezinye izinguquko zofuzo ezidluliswa ngaphambi kokuzalwa.

Uma une-CLL, umnkantsha wakho ukhiqiza ama-lymphocyte amaningi kakhulu - uhlobo lweseli elimhlophe. La ma-lymphocyte awasebenzi kahle. Zibangela ezinye izinkinga ngokungena endleleni yamanye amangqamuzana egazi akhiqizwayo.

Izimpawu ze-CLL zingahluka ngokuya ngesigaba noma ubukhulu besifo. Ungahle ungabi nezimpawu kusenesikhathi. Njengoba lesi sifo siqhubeka, izimpawu zingafaka:

• ama-lymph node akhulisiwe
• ukukhathala
• imfiva
• ukujuluka ebusuku
• ukuncipha komzimba
• ukutheleleka okuvamile
• ukugcwala kwesisu

Yenza i-aphoyintimenti nodokotela wakho uma uba nezimpawu ezingenhla. Lapho uthola ukuxilongwa ngokushesha, umbono wakho uba ngcono.

Izinga lokusinda leukemia engapheliyo ye-lymphocytic

I-CLL inezinga eliphakeme lokusinda kunamanye umdlavuza amaningi. Izinga lokusinda leminyaka emihlanu lizungeze amaphesenti angama-83. Lokhu kusho ukuthi amaphesenti angama-83 abantu abanalesi sifo bayaphila eminyakeni emihlanu ngemuva kokuxilongwa. Kodwa-ke, kulabo abangaphezu kweminyaka yobudala engama-75, izinga lokusinda leminyaka emihlanu lehlela ngaphansi kwamaphesenti angama-70. Njengoba abacwaningi beqhubeka nokufunda kabanzi nge-CLL, kuyacaca ukuthi kungaba nzima kanjani ukubikezela imiphumela. Kunezici eziningi kakhulu okufanele uzicabangele ukwelashwa nokusinda. Imiphumela yabantu abane-CLL iyinkimbinkimbi ngokungabikho noma ukutholakala kwezimpawu ezahlukahlukene zamaseli, njenge-IGHV, i-CD38, ne-ZAP70, kanye nezinguquko ezithile zofuzo.

Ngokusho kweNational Cancer Institute, ngo-2017 kuzoba namacala amasha alinganiselwa ku-20,100 e-CLL e-United States. Futhi lesi sifo sizodala ukuthi kube nokufa okulinganiselwa ku-4,660 ngo-2017.

Abanye abantu banengozi ephezulu yokuthuthukisa i-CLL. Lesi sifo sivame kakhulu emadodeni kunabesifazane, futhi sinamathuba amaningi okuhlasela labo abaneminyaka engaphezu kwengama-60. Empeleni, cishe amaphesenti angama-80 alabo abasanda kutholakala ukuthi bane-CLL bangaphezu kweminyaka engama-60 ubudala. AmaCaucasus nawo maningi amathuba okuthi bahlakulele lolu hlobo lomdlavuza.

Ngokuhambisana nobuhlanga nobulili, umlando womndeni we-CLL noma okunye ukuphazamiseka kwegazi nakho kwandisa ingozi yakho. Ukuchayeka kumakhemikhali athile afana ne-herbicides kanye ne-insecticide kubonakala kukhulisa ubungozi futhi.

Izici ezinomthelela ekubukeni kwe-lymphocytic leukemia engapheli

Sekukonke, i-lymphocytic leukemia engapheli inezinga eliphakeme lokusinda, kepha kunezici eziningana ezithonya umbono wakho. Lezi zinto zifaka isigaba sesifo nokuthi uphendula kahle kanjani ekwelashweni, kanye nezimpawu ezithile zeselula nezofuzo.

Ngemuva kokuxilongwa, isinyathelo esilandelayo ukubeka lesi sifo. Okwamanje kunezinhlelo ezimbili zokubeka iziteji ze-CLL: iRai neBinet.

I-Rai ivame kakhulu e-United States, kanti i-Binet isetshenziswa kakhulu eYurophu. Isiteji seRai sichaza izigaba ezi-5 kusuka ku-0 kuye ku-4. Ubungozi ukuthi kungenzeka ukuthi isifo sithuthuke ngokushesha kangakanani. Ukuphakama kwengozi, i-CLL kulindeleke ukuthi iqhubekele phambili ngokushesha okukhulu. Uhlelo lweBinet lusebenzisa u-A, B no-C.

Isiteji sinqunywa ngokuya ngezici ezahlukahlukene ezifana nokubalwa kwegazi nokubandakanyeka kwama-lymph node, isibindi, nobende. Imizila evulekile yokuxhumana phakathi kwakho nochwepheshe wakho womdlavuza, noma i-oncologist, ibalulekile. Ziwumthombo omuhle kakhulu wolwazi olusesikhathini maqondana nokwelashwa nokunakekelwa kwakho. Njengoba lesi sifo siyinkimbinkimbi, zinganikeza nokuholwa ngokuya ngecala lakho le-CLL.

Ukwelashwa kungahle kungadingeki ngokushesha uma imiphumela evela kumnkantsha wethambo lakho, ukuhlolwa kwe-imaging, nokuhlolwa kwegazi kuveza isigaba sokuqala esinobungozi obuphansi. Ubudala, ubungozi besifo kanye nezimpawu konke kudlala indima ekusizeni ukuthola izindlela zokwelashwa. UMayo Clinic ubika ukuthi abukho ubufakazi bokuthi ukwelashwa kusenesikhathi i-CLL kuzonweba izimpilo. Odokotela abaningi badela ukwelashwa kulesi sigaba sokuqala ukuze abantu bangatholi imiphumela emibi kanye nezinkinga ezingaba khona. Ngesikhathi sokuqala kodokotela be-CLL basibheka njalo isifo, futhi baqala ukwelashwa lapho siqhubeka.

Uma unesigaba esithuthuke kakhulu se-CLL esinobungozi obuphakeme, ukwelashwa okuhlukile kungakhuphula izinga lokusinda kwakho. Ukwelashwa kuvame ukufaka inhlanganisela yemithi yokwelapha ngamakhemikhali ukubulala amangqamuzana omdlavuza. Ungase futhi ube ukhetho lokufakelwa kabusha kwe-bone marrow stem cell. Kule nqubo, uzothola amangqamuzana egazi abantu abadala aphilile avela kumnikeli. Lokhu kungakhuthaza ukukhiqizwa kwamangqamuzana akho egazi anempilo.

Ngabe sesiseduze nokwelashwa?

Ezigulini ezisencane ezingazange zelashwe phambilini, ezisempilweni ephelele, futhi ezinophawu oluthile oluhle lweselula, inhlanganisela yokwelashwa ngamakhemikhali ebizwa ngeFCR (fludarabine, cyclophosphamide, rituximab) ikhombise isithembiso esikhulu. Ngokukamagazini i-Blood, lokhu kwelashwa kungadala ukusinda isikhathi eside futhi mhlawumbe kube ikhambi labantu abathile.

Inkinga ukuthi lokhu kwelashwa akuwona wonke umuntu. Labo abangaphezu kweminyaka engama-65 ubudala, abantu abanezinso ezingasebenzi kahle, kanye nalabo abanezinye izimo zezempilo kungenzeka bangakubekezeleli lokhu kwelashwa. Kwabanye abantu, kungakhuphula nengozi yokutheleleka kanye neminye imidlavuza.

Ukubhekana nokusekelwa kwe-leukemia engapheli ye-lymphocytic

Ukuphila nomdlavuza kudala imizwa ehlukahlukene. Ngezinye izinsuku uzozizwa umuhle, nezinye izinsuku, zingabi zizinhle kangako. Ngezinye izikhathi ungazizwa ukhungathekile, uthukuthele, wesaba, unovalo, noma unethemba. Noma ngabe usesigabeni esinobungozi obuphansi be-CLL futhi ungatholi ukwelashwa, ungesaba ukuthi isifo siyaqhubeka.

Veza imizwa yakho

Ungagcini imizwa yakho ifakwa ngaphakathi. Ungagcina imicabango kuwe ukuze ugweme ukucasula umndeni noma abangane. Kepha ukuveza indlela ozizwa ngayo kuyisihluthulelo sokubhekana nalesi sifo. Khuluma nelungu lomndeni elithenjiwe noma umngane ukuze uthole isiqinisekiso nokusekelwa, futhi uvumele ukudabuka. Kulungile ukukhala. Ezimweni eziningi, uzozizwa ungcono ngemuva kokukhishwa ngokomzwelo.

Uma ungakhululekile ukukhuluma nabanye ngesimo sakho, bhala phansi imizwa yakho encwadini. Buza nodokotela wakho ngamaqembu asekela umdlavuza. Noma ungakhuluma nomeluleki osebenza nabantu abanomdlavuza.

Zifundise

Ukuxilongwa komdlavuza kungafaka ukucindezeleka nokukhathazeka. Kepha ngokwazi nokuqonda kwakho kabanzi ngalesi simo, kuzoba lula ukwamukela iqiniso lakho elisha. I-American Cancer Society incoma ukuba ngummeli wakho. Musa ukulinda udokotela wakho ukuthi akufundise nge-CLL.

Cwaninga ngesimo bese uhlala usesikhathini ngezindlela zokwelashwa zakamuva ukuze ubuze imibuzo ecabangayo. Thatha amanothi ngesikhathi sokuqokwa kukadokotela wakho, bese ucela udokotela wakho ukuthi acacise imininingwane ongayiqondi. Kubalulekile futhi ukuthola imininingwane ethembekile uma ubheka ku-inthanethi. Buza udokotela wakho ngesincomo sokuthi ungafunda kuphi kabanzi ngesimo sakho.

Khuthala

Umsebenzi womzimba ungenye indlela yokubhekana nokuxilongwa kwe-CLL. Ukuzivocavoca umzimba kubalulekile ngoba umsebenzi wandisa ukukhiqizwa kobuchopho bakho bama-endorphin. Lawa ama-hormone "azizwa kahle". Ukuzivocavoca umzimba kuthuthukisa umbono wakho wengqondo. Kungakhuphula futhi amasosha omzimba wakho futhi kukusize ulwe nezifo. Thatha uhambo lokuhamba ngezinyawo noma lokuhamba ngebhayisikili, noma uthathe isigaba se-yoga noma elinye ikilasi lokuzivocavoca.

Susa ingqondo yakho esifo sakho

Kungaba nzima ukususa ingqondo yakho kumdlavuza. Enye indlela yokubhekana nakho ukuthola izinto ezimnandi ezingakusiza ekuphumuleni nasekuphumuleni. Hlola umsebenzi wokuzilibazisa, njengokuthwebula izithombe, ubuciko, umdanso, noma ubuciko. Ukuze uphumule, cabanga ngokuzindla ngezithombe eziqondisiwe. Le ndlela ikuvumela ukuthi ugxile ezithombeni ezinhle ukukusiza uphumule futhi wehlise ukucindezeleka. Futhi uma unosuku oluhle, sebenzisa amandla akho ukuze uphile impilo ngokugcwele, okungasusa ingqondo yakho empilweni yakho.