I-Cirrhosis ne-Hepatitis C: Ukuxhuma Kwayo, Ukubikezela, Nokuningi

-Delile

• Isifo sokuqina kwesibindi
• I-Hepatitis C ingabonakali
• Izimpawu zesifo sokuqina kwesibindi ngenxa yesifo sokusha kwesibindi kohlobo C
• Ukuthuthukela ku-cirrhosis
• Izinkinga ze-cirrhosis
• Ukwelashwa kwe-HCV ne-cirrhosis
• Isimo se-Cirrhosis

Isifo sokusha kwesibindi kohlobo C kungaholela ukuqina kwesibindi

Abanye e-United States banegciwane lesifo sokusha kwesibindi kohlobo C (HCV). Yize kunjalo abantu abaningi abatheleleke nge-HCV abazi ukuthi banayo.

Eminyakeni edlule, ukutheleleka nge-HCV kungadala umonakalo omkhulu esibindini. Kubantu bonke abangama-75 kuya kwabangu-85 abanesifo se-HCV esingapheliyo, phakathi kwabo kuzoba nesifo sokuqina kwesibindi. Ukutheleleka nge-HCV kuyimbangela ehamba phambili yomdlavuza wokuqina kwesibindi nomdlavuza wesibindi.

Isifo sokuqina kwesibindi

Isibindi isitho esikhipha ubuthi egazini futhi sakha izakhamzimba ezibalulekile. Ziningi izinto ezingalimaza isibindi. Ezinye zazo zifaka:

• ukuphuza ngokweqile
• izimuncagazi
• i-hepatitis

Ngokuhamba kwesikhathi, ukuvuvukala esibindini kudala ukulimala nokulimala unomphela (okubizwa nge-cirrhosis). Ngesikhathi se-cirrhosis, isibindi asikwazi ukuziphilisa. I-cirrhosis ingaholela ku:

• isifo sesibindi sokugcina
• umdlavuza wesibindi
• ukwehluleka kwesibindi

Kunezigaba ezimbili ze-cirrhosis:

• Isifo sokuqina kwesibindi esikhokhelwe kusho ukuthi umzimba usasebenza yize kunciphile ukusebenza kwesibindi kanye nezibazi.
• Isifo sokuqina kwesibindi esinciphile kusho ukuthi imisebenzi yesibindi iyawohloka. Izimpawu ezinzima zingavela, njengokuhluleka kwezinso, ukuphuma kwegazi le-variceal, kanye ne-hepatic encephalopathy.

I-Hepatitis C ingabonakali

Kungaba nezimpawu ezimbalwa ngemuva kokutheleleka nge-HCV kokuqala. Abantu abaningi abane-hepatitis C abazi nokuthi banesifo esisongela impilo.

I-HCV ihlasela isibindi. Abantu abaningi abadaluliwe baba nokutheleleka okungapheli ngemuva kokutheleleka kokuqala nge-HCV. Ukutheleleka okungamahlalakhona kwe-HCV kudala ukuvuvukala nokonakala esibindini. Kwesinye isikhathi isimo singase singatholakali iminyaka engu-20 noma engu-30.

Izimpawu zesifo sokuqina kwesibindi ngenxa yesifo sokusha kwesibindi kohlobo C

Ungahle ungabi nazimpawu ze-cirrhosis kuze kube nomonakalo omkhulu esibindini sakho. Uma uhlangabezana nezimpawu, lokhu kungafaka:

• ukukhathala
• isicanucanu
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• ukopha noma ukulimaza kalula
• isikhumba esilumayo
• ukushintsha kombala okuphuzi emehlweni nasesikhumbeni (i-jaundice)
• ukuvuvukala kwemilenze
• uketshezi esiswini (ascites)
• ukuhlolwa kwegazi okungajwayelekile, njenge-bilirubin, i-albhamuin, kanye nemingcele ye-coagulation
• imithambo ekhulisiwe esiswini nasesiswini esingaphezulu esingopha (i-variceal hemorrhage)
• ukungasebenzi kahle kwengqondo ngenxa yokwakheka kobuthi (i-hepatic encephalopathy)
• ukutheleleka kolwelwesi lwesisu kanye nama-ascites (bacterial peritonitis)
• ukuhluleka kwezinso nesibindi okuhlangene (hepatorenal syndrome)

I-biopsy yesibindi izokhombisa ukusikeka, okungaqinisekisa ubukhona be-cirrhosis kubantu abane-HCV.

Ukuhlolwa kweLab kanye nokuhlolwa ngokomzimba kunganela udokotela wakho ukuthola isifo sesibindi esithuthukile ngaphandle kwe-biopsy.

Ukuthuthukela ku-cirrhosis

Ngaphansi kwengxenye yesine yabantu abane-HCV bazoba nesifo sokuqina kwesibindi. Kodwa, izici ezithile zingakhuphula ubungozi bakho bokuqina kwesibindi, kufaka phakathi:

• ukusetshenziswa kotshwala
• ukutheleleka nge-HCV nelinye igciwane (njenge-HIV noma i-hepatitis B)
• amazinga aphezulu wensimbi egazini

Noma ngubani onesifo esingelapheki se-HCV kufanele agweme utshwala. I-Cirrhosis nayo ingasheshisa kubantu abadala kunama-45 njenge-fibrosis nokwanda kwesibazi. Ukwelapha ukutheleleka nge-HCV kubantu abasha kungasiza ekuvimbeleni ukuqhubekela phambili ku-cirrhosis.

Izinkinga ze-cirrhosis

Kubalulekile ukuhlala uphilile uma unesifo sokuqina kwesibindi. Qinisekisa ukugcina konke ukugoma kusesikhathini, kufaka phakathi:

• i-hepatitis B
• i-hepatitis A
• umkhuhlane
• inyumoniya

I-cirrhosis ingashintsha indlela igazi eligeleza ngayo emzimbeni wakho. Ukuqubuka kungavimbela ukugeleza kwegazi ngesibindi.

Igazi lingahle lidlulele emithanjeni emikhulu esiswini nasesimingxenyeni. Le mithambo yegazi ingakhulisa futhi iqhume, ibangele ukopha esiswini. Qiniseka ukuthi ubheka ukopha okungavamile.

Umdlavuza wesibindi kungenye inkinga yokuqina kwesibindi. Udokotela wakho angasebenzisa ukuhlolwa kwe-ultrasound kanye nokuhlolwa kwegazi njalo ezinyangeni ezimbalwa ukuhlola umdlavuza. Ezinye izinkinga ze-cirrhosis zifaka:

• i-gingivitis (isifo sezinsini)
• isifo sikashukela
• izinguquko endleleni okwenziwa ngayo imithi emzimbeni wakho

Ukwelashwa kwe-HCV ne-cirrhosis

Ama-antivirals asebenza kahle, asebenza ngqo kanye neminye imishanguzo ye-HCV ingelapha isifo sokuqina kwesibindi sokuqala. Le mithi inganciphisa ukuqhubeka kwesifo sesibindi nokuhluleka kwesibindi.

Lapho ukuqina kwesibindi kuthuthuka, ukwelashwa kuba nzima kakhulu ngenxa yezinkinga ezinjenge:

• ascites
• i-anemia
• ukucabanga kwengqondo

Lezi zinkinga zingenza kungaphephile ukusebenzisa eminye imithi. Ukufakelwa kwesibindi kungaba ukuphela kwendlela yokwelashwa.

Ukufakelwa kwesibindi kuwukuphela kokwelapha okusebenzayo kwe-cirrhosis esezingeni eliphakeme. Iningi labantu abathola ukufakelwa kwesibindi i-hepatitis C baphila okungenani iminyaka emihlanu ngemuva kokufakwa. Kodwa, ukutheleleka nge-HCV kuvame ukubuya. Yimbangela ejwayelekile yokufakelwa kwesibindi e-United States.

Isimo se-Cirrhosis

Abantu abane-cirrhosis bangaphila amashumi eminyaka, ikakhulukazi uma kutholakala kusenesikhathi futhi baphathwa kahle.

Cishe amaphesenti ama-5 kuye kwayi-20 abantu abane-hepatitis C engapheli abazoba nesifo sokuqina kwesibindi. Unalokho engqondweni, kuthatha iminyaka engama-20 kuye kwengama-30 ukuthi i-cirrhosis ikhule kuleso sabantu.

Ukusebenzisa ama-antivirals asebenza ngqo kungasiza ekunciphiseni noma ekuvimbeleni ukuqhubeka kwe-cirrhosis. Uma ishiywe ingalashwa, i-cirrhosis ingaholela ekuhlulekeni kwesibindi.

Ukuze ulondoloze impilo yesibindi, zama okulandelayo:

• gcina impilo ejwayelekile
• gwema utshwala
• thola ukunakekelwa njalo kwezokwelapha
• welapha ukutheleleka okuyisisekelo kwe-HCV

Uzophinde ufune ukusebenza nodokotela we-gastroenterologist noma i-hepatologist ukuthola ukwelashwa okuhle kakhulu nokuqapha noma yiziphi izinkinga.