Qedela Ukuhlolwa Kwegazi

-Delile

• Kuyini ukuhlolwa kwegazi okuhambisanayo?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwegazi okuhambisanayo?
• Kwenzekani ngesikhathi sokuhlolwa kwegazi okuhambisanayo?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi ekuhlolweni kwegazi?
• Isho ukuthini imiphumela?
• Izinkomba

Kuyini ukuhlolwa kwegazi okuhambisanayo?

Isivivinyo sokugcwalisa igazi silinganisa inani noma umsebenzi wamaprotheni ahambisanayo egazini. Ukugcwalisa amaprotheni ayingxenye yohlelo lokugcwalisa. Lolu hlelo lwakhiwa iqembu lamaprotheni asebenza namasosha omzimba ukukhomba nokulwa nezinto ezibanga izifo njengamagciwane namagciwane.

Kunamaprotheni ayisishiyagalolunye amakhulu ahambisanayo. Zibhalwe ukuthi yi-C1 nge-C9. Ukugcwalisa amaprotheni kungalinganiswa ngamunye noma ndawonye. Amaprotheni e-C3 no-C4 angamaprotheni ahambisana kakhulu avivinywa kakhulu. Ukuhlolwa kwe-CH50 (kwesinye isikhathi okubizwa nge-CH100) kukala inani nomsebenzi wawo wonke amaprotheni amakhulu ahambisanayo.

Uma ukuhlolwa kukhombisa ukuthi amazinga wakho wokugcwalisa amaprotheni awejwayelekile noma ukuthi amaprotheni awasebenzi namasosha omzimba njengoba kufanele, kungaba uphawu lwesifo sokuzilimaza noma enye inkinga enkulu yempilo.

Amanye amagama: complement antigen, compliment activity C3, C4, CH50, CH100, C1 C1q, C2

Kusetshenziselwa ini?

Ukuhlolwa kwegazi okusizayo kuvame ukusetshenziselwa ukuxilonga noma ukuqapha ukuphazamiseka okuzenzakalelayo okufana nalokhu:

• I-Lupus, isifo esingelapheki esithinta izingxenye eziningi zomzimba, kufaka phakathi amalunga, imithambo yegazi, izinso nobuchopho
• I-rheumatoid arthritis, isimo esidala ubuhlungu nokuvuvukala kwamalunga, ikakhulukazi ezandleni nasezinyaweni

Ingasetshenziselwa ukusiza ukuxilonga izifo ezithile ezibangelwa amagciwane, igciwane noma ukhunta.

Kungani ngidinga ukuhlolwa kwegazi okuhambisanayo?

Ungadinga ukugcwaliswa kokuhlolwa kwegazi uma unezimpawu zesifo esizimele, ikakhulukazi i-lupus. Izimpawu ze-lupus zifaka:

• Ukuqhuma okwenziwe njengovemvane emakhaleni nasezihlathini zakho
• Ukukhathala
• Izilonda zomlomo
• Ukulahleka kwezinwele
• Ukuzwela ekukhanyeni kwelanga
• Ama-lymph node avuvukile
• Ubuhlungu besifuba lapho uphefumula ngokujulile
• Ubuhlungu obuhlangene
• Imfiva

Ungadinga futhi lolu vivinyo uma welashelwa i-lupus noma enye i-autoimmune disorder. Ukuhlolwa kungakhombisa ukuthi umuthi usebenza kahle kangakanani.

Kwenzekani ngesikhathi sokuhlolwa kwegazi okuhambisanayo?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi noma yimaphi amalungiselelo akhethekile okuhlola umphelelisi wegazi.

Ingabe zikhona izingozi ekuhlolweni kwegazi?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa amanani aphansi kunalawo ajwayelekile noma umsebenzi owehlisiwe wamaprotheni ahambisanayo, kungasho ukuthi unenye yalezi zimo ezilandelayo:

• ILupus
• Isifo samathambo
• Isifo sokuqina kwesibindi
• Izinhlobo ezithile zesifo sezinso
• I-hereditary angioedema, isifo esingajwayelekile kepha esibi kakhulu sohlelo lomzimba. Kungadala ukuvuvukala kobuso nemigwaqo yomoya.
• Ukungondleki
• Ukutheleleka okuphindaphindiwe (ngokuvamile okuyi-bacterial)

Uma imiphumela yakho ikhombisa ukuphakama kunamanani ajwayelekile noma umsebenzi owandisiwe wamaprotheni wokuqinisa, kungasho ukuthi unesimo esisodwa salezi ezilandelayo:

• Izinhlobo ezithile zomdlavuza, njenge-leukemia noma i-non-Hodgkin lymphoma
• I-ulcerative colitis, isimo lapho ulwelwesi lwamathumbu amakhulu ne-rectum luvuvuka khona

Uma welashelwa i-lupus noma esinye isifo se-autoimmune, amanani akhuphukile noma umsebenzi wamaprotheni ahambisanayo kungasho ukuthi ukwelashwa kwakho kuyasebenza.

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Izinkomba

1. I-HSS: Isibhedlela Sokuhlinzwa Okukhethekile [i-Inthanethi]. ENew York: Isibhedlela Sokuhlinzwa Okukhethekile; c2020. Ukuqonda Ukuhlolwa Kwelabhoratri Nemiphumela YeLupus (SLE); [kubuyekezwe i-2019 Jul 18; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-4]. Kutholakala ku: https://www.hss.edu/conditions_understanding-laboratory-tests-and-results-for-systemic-lupus-erythematosus.asp
2. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Ukuqina kwesibindi; [kubuyekezwe i-2019 Oct 28; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/conditions/cirrhosis
3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Phelelisa; [kubuyekezwe ngo-2019 Dec 21; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/complement
4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. ILupus; [kubuyekezwe ngo-2020 Jan 10; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/conditions/lupus
5. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001-2020. Isifo samathambo; [kubuyekezwe i-2019 Oct 30; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-3]. Kutholakala ku: https://labtestsonline.org/conditions/rheumatoid-arthritis
6. ILupus Foundation of America [Inthanethi]. Washington D.C .: ILupus Foundation of America; c2020. Iglosari yokuhlolwa kwegazi kwe-lupus; [kucashunwe ngo-2020 Feb 28]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.lupus.org/resource/glossary-of-lupus-blood-tests
7. ILupus Research Alliance [i-Intanethi]. ENew York: I-Lupus Research Alliance; c2020. Mayelana neLupus; [kucashunwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/about-lupus
8. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2020 Feb 28]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. Ukugcwalisa: Ukubuka konke; [kubuyekezwe ngo-2020 Feb 28; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/complement
10. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. I-angioedema yefa: Ukubuka konke; [kubuyekezwe ngo-2020 Feb 28; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala ku: https://ufhealth.org/hereditary-angioedema
11. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. I-lupus erythematosus ehlelekile: Ukubuka konke; [kubuyekezwe ngo-2020 Feb 28; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/systemic-lupus-erythematosus
12. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. I-Ulcerative colitis: Ukubuka konke; [kubuyekezwe ngo-2020 Feb 28; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/ulcerative-colitis
13. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: Complement C3 (Igazi); [kucashunwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=complement_c3_blood
14. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: Complement C4 (Igazi); [kucashunwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=complement_c4_blood
15. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2020. Imininingwane Yezempilo: Isivivinyo Sokugcwalisa iLupus: Ukubuka konke kwesihloko; [kubuyekezwe 2019 Ephreli 1; kukhonjiwe ngo-2020 Feb 28]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/complement-test-for-lupus/hw119796.html

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.