I-cortisol ephezulu: kungaba yini, izimpawu nokuthi ungalanda kanjani

-Delile

• Izimbangela eziyinhloko
• Izimpawu ezingenzeka nemiphumela emzimbeni
• Indlela yokwehlisa amazinga e-cortisol
• Kungani ukukhulelwa kwandisa i-cortisol

I-cortisol ephezulu idalwa ukusetshenziswa kwama-corticosteroids izinsuku ezingaphezu kwezingu-15, noma ngokwanda kokukhiqizwa kwaleli hormone ezingxenyeni ze-adrenal, ngenxa yengcindezi engapheli noma isimila esithile.

Lapho kusolwa le nkinga, ngenxa yemiphumela emibi ye-cortisol eyeqile, njengokuzuza kwesisindo, umfutho wegazi ophakeme, isifo sikashukela kanye ne-osteoporosis, udokotela ojwayelekile angayalela ukuhlolwa kwe-cortisol, ngokulinganisa igazi, umchamo noma amathe.

Ukulawulwa kwaleli hormone kwenziwa ngokuvivinya umzimba nokusetshenziswa kokudla okulawula ukucindezeleka noshukela wegazi, njengama-yam, ama-oats, amaqanda, i-flaxseed nobisi kanye nezinye izinto, isibonelo. Kodwa-ke, lapho amazinga aphezulu e-cortisol enzima, ukwelashwa okususelwa kuzidakamizwa noma nokuhlinzwa, okuholwa yi-endocrinologist, kuyadingeka.

Izimbangela eziyinhloko

Ukusetshenziswa kwezidakamizwa ze-corticosteroid, njenge-prednisone noma i-dexamethasone, izinsuku ezingaphezu kwezingu-15 kuyindlela ejwayelekile kakhulu ye-cortisol eyeqile egazini, kepha ezinye izimbangela yilezi:

• Ukucindezeleka okungapheli nokulala okungajwayelekile: bangakwazi ukuhlehlisa ukukhiqizwa kwe-cortisol futhi bakwenze ukuthi ikhule emzimbeni;
• Ukungasebenzi kahle kwezindlala ze-adrenal: kubangelwa ukuba khona kwesimila noma ukwehliswa kwamaseli aso, okungaveza i-cortisol eyeqile;
• Isigaxa sobuchopho: kungashukumisa uketshezi lwe-cortisol yizindlala ze-adrenal.

Ukucindezeleka kuvame ukudala ushintsho oluncane kumanani we-cortisol, kuyilapho ukwanda okukhulu kakhulu futhi okukhulu kubangelwa ushintsho oluqondile kuzindlala nobuchopho.

Izimpawu ezingenzeka nemiphumela emzimbeni

Lapho ikhiqizwa kwizindlala ze-adrenal, i-cortisol ikhishwa ekusakazweni ngenhloso yokulawula imisebenzi yomzimba. Kodwa-ke, lapho ngokweqile, futhi isikhathi eside, kungadala imiphumela emibi efana nale:

• Isisindo esandisiwe, umjikelezo okhalweni nokuqunjelwa, ngokugcinwa koketshezi, nokwabiwa kabusha kwamafutha omzimba;
• Isifo sikashukela namazinga aphezulu kashukela egazini, yokuvuselela isenzo sesibindi ukukhiqiza i-glucose;
• I-osteoporosis, ngokunciphisa ukumuncwa kwe-calcium ngumzimba nokunciphisa i-collagen;
• Ukukhuphuka kwengcindezi, ukucasuka kanye nokudangala, ngokubangela ukukhishwa kwe-adrenaline nangesenzo esiqondile ebuchosheni;
• I-cholesterol ephezulu, ngokwandisa ukukhiqizwa kwamafutha ngesibindi nokukhishwa kwegazi;
• Ukuncipha kwemisipha nobuthakathaka, ngoba kunciphisa ukukhiqizwa kwamaprotheni futhi kwehlisa amaprotheni ezicubu;
• Ingcindezi ephezulu, ngokubangela ukugcinwa kwe-sodium kanye neziphuzo, nokwandisa ukukhishwa kwe-adrenaline ekusakazeni;
• Ukwehliswa kokuvikelwa komzimba, ngokuvimbela ukuvuvukala nokuzivikela komzimba;
• Izinga elikhulisiwe lamahomoni wesilisa emzimbeni, okungabesifazane okungadala izimpawu ezingathandeki, njengezinwele ezeqile, ukuqina kwezwi nokulahleka kwezinwele;
• Izinguquko kumjikelezo wokuya esikhathini kanye nobunzima bokukhulelwa, yokwehlisa umthetho ama-hormone abesifazane;
• Ukuthambeka esikhunjeni, ukwanda kwamanxeba, izilonda zesikhumba nokwelulwa, ngokuncipha kwe-collagen nokunciphisa umphumela wokuphulukisa komzimba.

Igama lalezi zinguquko ezibangelwe ukwanda okungapheli kwe-cortisol yi-Cushing's syndrome. Lapho kusolwa lesi sifo noma ukwanda kwe-cortisol, udokotela ojwayelekile noma i-endocrinologist anga-oda ukuhlolwa kwegazi, umchamo noma amathe, okukhombisa ukwanda kwale hormone emzimbeni.

Uma lokhu kuhlolwa kunenani eliphezulu, udokotela uzobe esephenya imbangela ye-cortisol eyeqile, ngokuhlolwa komtholampilo, nange-tomography noma nge-MRI, isisu nobuchopho, i-PET noma i-scintigraphy.

Thola kabanzi mayelana nokuthi kwenziwa kanjani ukuhlolwa kwe-cortisol.

Indlela yokwehlisa amazinga e-cortisol

Njengoba i-cortisol ixhunyaniswe kakhulu nesistimu yemizwa, indlela enhle yokulawula i-cortisol ukunciphisa ukucindezeleka nokukhathazeka, nge-psychotherapy nangesikhathi sokuzilibazisa. Ngaphezu kwalokho, ukwenza ukuvivinya umzimba nokudla ukudla okunothe ngamaprotheni ne-potassium, njengamaqanda, ubisi nemikhiqizo yobisi, inhlanzi, i-oats, ama-alimondi, ama-chestnut, i-chia nembewu yefilakisi nakho kungasiza.

Kakade, uma ukweqisa kwe-cortisol kubangelwa ukusetshenziswa kwama-corticosteroids, kufanele isuswe kancane kancane, ngezinsuku ezimbalwa, ngokuholwa ngudokotela ojwayelekile noma i-endocrinologist.

Lapho imbangela yokwanda, i-cortisol iba yimbi kakhulu, njengesimila, ukwelashwa kwenziwa ngokusetshenziswa kwemithi yokulawula inani lehomoni, njenge-metyrapone, i-aminoglutetimide, ngokwesibonelo, nokuhlinzwa ukususa lesi sifo , okuzonqunywa futhi kuhlelwe phakathi kwesiguli, udokotela wezifo zokuphela komzimba nodokotela ohlinzayo.

Funda ukuthi ungenza kanjani ukwelashwa kwemvelo okusiza ukulawula i-cortisol ephezulu.

Kungani ukukhulelwa kwandisa i-cortisol

Amazinga aphezulu e-cortisol ajwayelekile ekukhulelweni, ikakhulukazi emavikini okugcina okukhulelwa, njengoba i-placenta ikhiqiza i-hormone, eyaziwa njenge-CRH, evuselela ukuhlanganiswa kwe-cortisol, inyuse amazinga ayo emzimbeni womuntu okhulelwe.

Kodwa-ke, futhi ngokuphambene nalokho okwenzeka ngaphandle kokukhulelwa, lawa mazinga aphezulu e-cortisol ngesikhathi sokukhulelwa kubonakala engayithinti impilo kamama noma yengane, njengoba kukhula okudingekayo ukugcina ukukhulelwa okunempilo futhi kubonakala sengathi kuyasiza ukukhula kwengane kanye nengqondo yokukhula kwamaphaphu. Ngalesi sizathu, izingane ezizalwe ngaphambi kwesikhathi zinamathuba amaningi okuhlangabezana nezinkinga zokuphefumula. Ngakho-ke, lapho owesifazane okhulelwe esengozini enkulu yokubeletha ngaphambi kwesikhathi, kuvamile ukuthi udokotela obelethayo ancoma ukwenziwa kwama-corticosteroids okwenziwa, ukusiza ekukhuleni kwezitho zomntwana.

Izinkinga ze-cortisol ephezulu, njenge-Cushing's syndrome, zivame kakhulu ngesikhathi sokukhulelwa nangesikhathi sokubeletha, njengoba amazinga e-cortisol ethambekele ekuweleni kumanani ajwayelekile ngemuva kokuzalwa kwengane.