Okudingeka Ukwazi Nge-DHT nokulahleka Kwezinwele

-Delile

• Yini i-DHT?
• Yini eyenziwa yi-DHT?
• Ukuba ne-DHT encane kakhulu
• Kungani i-DHT ithinta abantu ngokwehlukile
• Ukuxhumeka kwe-DHT kubalding
• I-DHT vs. testosterone
• Ungayinciphisa kanjani i-DHT
• I-Finasteride
• I-Minoxidil
• I-Biotin
• Amagxolo ePygeum
• Amafutha embewu yamathanga
• Ikhafeyini
• Uvithamini B-12 no-B-6
• Imiphumela emibi ye-DHT blocker
• Ezinye izimbangela zokulahleka kwezinwele
• I-Alopecia areata
• I-lichen planus
• Izimo ze-thyroid
• Isifo seCeliac
• Ukutheleleka kwesikhumba
• Izinwele zoqalo
• Ukudla okudlela endlini

Yini i-DHT?

Ukulinganisa iphethini yowesilisa, okubizwa nangokuthi i-alopecia ye-androgenic, ngesinye sezizathu ezivame kakhulu ukuthi amadoda alahlekelwe yizinwele njengoba zikhula.

Abesifazane nabo bangaluthola lolu hlobo lokulahleka kwezinwele, kepha akuvamile kakhulu. Cishe abesifazane abayizigidi ezingama-30 e-United States banalolu hlobo lokulahleka kwezinwele uma kuqhathaniswa nabesilisa abayizigidi ezingama-50.

Ama-hormone ocansi emzimbeni kukholakala ukuthi yiyona nto ebaluleke kakhulu ekulahlekelweni kwezinwele zamaphethini wesilisa.

IDihydrotestosterone (DHT) iyi-androgen. I-androgen iyi-hormone yezocansi enikela ekuthuthukiseni lokho okucatshangwa njengezici zocansi "zesilisa", njengezinwele zomzimba. Kepha futhi kungenza ukuthi ulahlekelwe izinwele zakho ngokushesha nangaphambi kwalokho.

Kukhona izindlela zokwelashwa ezihlose ukwehlisa ukuqala kwempandla yamadoda ngokukhomba ngqo i-DHT. Ake sixoxe ngokuthi i-DHT isebenza kanjani, ukuthi i-DHT ihlobana kanjani nezinwele zakho kanye ne-testosterone, nokuthi yini ongayenza ukumisa, noma okungenani ukubambezela, ukubala kwephethini yowesilisa.

Yini eyenziwa yi-DHT?

I-DHT itholakala ku-testosterone. I-testosterone yi-hormone ekhona kwabesilisa nabesifazane. I-DHT ngama-androgens, noma ama-hormone anikela kuzici zobulili besilisa lapho udlula ebusheni. Lezi zimfanelo zifaka:

• izwi elijulile
• ukwanda kwezinwele zomzimba nobukhulu bemisipha
• ukukhula kwesitho sangasese sowesilisa, i-scrotum, namasende njengoba kuqala ukukhiqizwa kwesidoda
• izinguquko ekutheni amafutha agcinwa kanjani emzimbeni wakho

Njengoba ukhula, i-testosterone ne-DHT kunezinye izinzuzo eziningi emzimbeni wakho, njengokugcina isisindo sakho semisipha yonke nokukhuthaza impilo yezocansi nokuzala.

Abesilisa ngokuvamile bane-testosterone eningi emizimbeni yabo. Cishe amaphesenti ayi-10 e-testosterone kubo bonke abantu abadala aguqulwa abe yi-DHT ngosizo lwe-enzyme ebizwa nge-5-alpha reductase (5-AR).

Uma igeleza ngokukhululeka egazini lakho, i-DHT ingabe isixhuma kuma-receptors kuzinwele zezinwele ekhanda lakho, ibenze banciphe futhi bangabe besakwazi ukuxhasa ikhanda lezinwele eliphilile.

Futhi amandla we-DHT okudala ukulimala adlula izinwele zakho. Ucwaningo luxhumanise i-DHT, ikakhulukazi amazinga ayo aphezulu ngokungajwayelekile, ku:

• ukuphulukiswa kancane kwesikhumba ngemuva kokulimala
• i-prostate ekhulisiwe
• umdlavuza wendlala yabesilisa
• isifo senhliziyo

Ukuba ne-DHT encane kakhulu

Amazinga aphezulu e-DHT angakhuphula ubungozi bakho ezimweni ezithile, kepha ukuba ne-DHT encane kakhulu kungadala nezinkinga ekukhuleni kwakho kwezocansi njengoba usudlula ebusheni.

I-DHT ephansi ingadala ukubambezeleka ekuqaleni kokuthomba kubo bonke ubulili. Ngaphandle kwalokho, i-DHT ephansi ayibonakali inethonya elikhulu kwabesifazane, kepha emadodeni, i-DHT ephansi ingadala:

• ukukhula sekwedlule isikhathi noma okungaphelele kwezitho zobulili, njengepipi noma amasende
• izinguquko ekusatshalalisweni kwamafutha omzimba, zidala izimo ezifana ne-gynecomastia
• ukwanda engcupheni yokuqhamuka kwezimila zesibindi zesibindi

Kungani i-DHT ithinta abantu ngokwehlukile

Ukusebenza kwakho ekulahlekelweni kwezinwele kungokofuzo, okusho ukuthi kudluliselwe emndenini wakho.

Isibonelo, uma ungowesilisa futhi ubaba wakho ehlangabezana nokulinganisa kwephethini yowesilisa, kungenzeka ukuthi uzobonisa iphethini yokulinganisa efanayo njengoba ukhula. Uma usuvele uthambekele ekushayeni iphethini yowesilisa, umphumela wokuncipha kwe-follicle we-DHT uvame ukubonakala kakhulu.

Usayizi nokuma kwekhanda lakho nakho kungaba nomthelela ekutheni i-DHT inciphise masinyane kanjani izintambo zakho.

Ukuxhumeka kwe-DHT kubalding

Izinwele yonke indawo emzimbeni wakho zikhula ngaphandle kwezakhiwo ngaphansi kwesikhumba sakho ezaziwa ngokuthi ama-follicles, okuyiziphilisi ezincane kakhulu eziqukethe umucu owodwa wezinwele.

Izinwele ezingaphakathi kwesikhumba ngokuvamile zihamba ngomjikelezo wokukhula oqhubeka cishe iminyaka emibili kuya kweyisithupha. Noma ngabe uphuca noma ugunda izinwele zakho, izinwele ezifanayo zizokhula zibuye ziphume kuphololi kusukela empandeni yezinwele eziqukethwe ngaphakathi kohlu.

Ekupheleni kwalo mjikelezo, izinwele zingena kulokho okwaziwa njengesigaba sokuphumula ngaphambi kokugcina ziwe ezinyangeni ezimbalwa kamuva. Ngemuva kwalokho, i-follicle ikhiqiza izinwele ezintsha, futhi umjikelezo uqala futhi.

Amazinga aphezulu ama-androgens, kufaka phakathi i-DHT, anganciphisa izinwele zakho zezinwele futhi anciphise lo mjikelezo, okwenza izinwele zikhule zibukeke zincane futhi ziqhekeke kakhulu, futhi ziphume ngokushesha. I-DHT nayo ingakwenza kuthathe isikhathi eside ukuthi izintambo zakho zikhule izinwele ezintsha uma kuphuma izinwele ezindala.

Abanye abantu bathinteka kakhulu kule miphumela ye-DHT ezinweleni zekhanda ngokususelwa okwehlukahluka kofuzo lwabo lwe-androgen receptor (AR). Ama-androgen receptors amaprotheni avumela ama-hormone afana ne-testosterone ne-DHT ukuthi abophele kuwo. Lo msebenzi obophayo uholela ezinqubweni ezijwayelekile zamahomoni njengokukhula kwezinwele zomzimba.

Kepha ukuhlukahluka kuhlobo lwe-AR kungakhuphula ukwamukelwa kwe-androgen kuzinhlayiya zakho zekhanda, okwenza ube sethubeni lokulahlekelwa yiphethini yesilisa.

I-DHT vs. testosterone

I-testosterone iyi-androgen eningi kakhulu futhi esebenzayo emzimbeni wesilisa. Inesibopho sezinqubo eziningi zocansi nezomzimba, kufaka phakathi:

• ukulawula amazinga e-androgen emzimbeni wonke
• elawula ukukhiqizwa kwesidoda
• ukulondolozwa kwamathambo nobukhulu bemisipha
• kusiza ukusabalalisa amafutha emzimbeni wonke
• ulawula imizwa nemizwelo yakho

I-DHT iyihlumela le-testosterone. I-DHT nayo ibamba iqhaza kweminye imisebenzi efanayo yezocansi kanye nezinqubo zomzimba njenge-testosterone, kodwa empeleni inamandla kakhulu. I-DHT ingabopha kwi-androgen receptor isikhathi eside, ikhuphule umthelela wokukhiqizwa kwe-testosterone emzimbeni wakho wonke.

Ungayinciphisa kanjani i-DHT

Kunemithi eminingi yokulahleka kwezinwele okuhlobene ne-DHT, futhi eminingi yayo ibhekiswe ngqo ekukhiqizeni i-DHT nokubopha kwe-receptor. Kunezinhlobo ezimbili eziyinhloko:

• Abavimba. Lokhu kuvimbela i-DHT ekuzibophezeleni kuma-receptors e-5-AR, kufaka phakathi lawo atholakala ezinhlakeni zezinwele zakho ezingavumela i-DHT ukuthi inciphise izintambo
• Izivimbeli. Lokhu kunciphisa ukukhiqizwa komzimba wakho kwe-DHT.

I-Finasteride

I-Finasteride (i-Proscar, i-Propecia) ngumuthi odluliselwa ngomlomo, odokotela kuphela. Kubhalwe ukuthi okungenani kunamaphesenti angama-87 empumelelo kumuntu oyedwa kwabesilisa abangama-3,177, enemiphumela emibi embalwa ebonwayo.

I-Finasteride ibopha amaprotheni we-5-AR ukuvimba i-DHT ekuzibopheni nayo. Lokhu kusiza ukugcina i-DHT ingabophi kuma-receptors kuzinwele zakho zezinwele futhi iyigcine inganciphi.

I-Minoxidil

I-Minoxidil (i-Rogaine) yaziwa njenge-peripheral vasodilator. Lokhu kusho ukuthi kusiza ukunweba nokukhulula imithambo yegazi ukuze igazi lidlule kalula.

Ngokuvamile isetshenziswa njengomuthi womfutho wegazi. Kepha i-minoxidil nayo ingasiza ukukhuthaza ukukhula kwezinwele lapho isetshenziswa ngokwezihloko ekhanda lakho.

I-Biotin

I-Biotin, noma i-vitamin H, i-vitamin B yemvelo esiza ukuguqula okunye kokudla neziphuzo ozisebenzisayo zibe amandla umzimba wakho ongazisebenzisa.

I-Biotin ibuye isize ukukhulisa nokugcina amazinga e-keratin, uhlobo lwamaprotheni akhona ezinweleni zakho, kuzipikili nasesikhunjeni. Ucwaningo aluqinisekisi ukuthi kungani i-biotin ibalulekile emazingeni e-keratin yomzimba wakho. Kepha ucwaningo lwango-2015 luphakamisa ukuthi i-biotin ingasiza ukuvuselelwa kwezinwele futhi igcine nezinwele ezikhona zingawi.

Ungathatha i-biotin njengesengezo somlomo, kodwa futhi ikhona kwizikhupha zamaqanda, amantongomane, nakuzinhlamvu ezigcwele.

Amagxolo ePygeum

I-Pygeum umuthi okhishwe emagxolweni esihlahla se-cherry sase-Afrika. Ngokuvamile kutholakala njengesengezo semithi esithathwe ngomlomo.

Kuyaziwa kahle njengokwelashwa okungase kube nenzuzo ye-prostate ekhulisiwe ne-prostatitis ngenxa yekhono layo lokuvimba i-DHT. Ngenxa yalokhu, futhi kucatshangwa ukuthi kungenzeka kube ukwelashwa kokulahleka kwezinwele okuhlobene ne-DHT, nakho. Kodwa kunocwaningo oluncane kakhulu lokuxhasa ukusetshenziswa kwe-pygeum bark kuphela njenge-block blocker ye-DHT ephumelelayo.

Amafutha embewu yamathanga

Amafutha embewu yamathanga kungenye i-DHT blocker ekhonjiswe ukuthi iphumelele.

Amadoda angama-76 anempandla eyiphethini yabesilisa akhombise ukwanda ngamaphesenti angama-40 ngesilinganiso sezinwele zesikhumba ngemuva kokuthatha ama-milligram angama-400 kawoyela wembewu wethanga nsuku zonke amasonto angama-24.

Ikhafeyini

Ucwaningo oluncane kakhulu olukhona lokuthi i-caffeine ingakhuthaza yini ukukhula kwezinwele. Kepha kusikisela ukuthi i-caffeine ingasiza ekuvikeleni ukulahleka kwezinwele ngo:

• okwenza izinwele zikhule zibe zinde
• ukunweba isigaba sokukhula kwezinwele
• ukugqugquzela ukukhiqizwa kwe-keratin

Uvithamini B-12 no-B-6

Ukushoda kumavithamini B, ikakhulukazi i-B-6 noma i-B-12, kungadala izimpawu eziningi, kufaka phakathi ukuncipha kwezinwele noma ukulahleka kwezinwele.

Amavithamini e-B ayizakhamzimba ezibalulekile empilweni yakho yonke, kanti ngenkathi uthatha izithasiselo ze-B-12 noma ze-B-6 kungahle kungakusizi ukubuyisela izinwele ezilahlekile, zingasiza ekwenzeni izinwele zakho ziqine futhi zibe nempilo ngokuthuthukisa ukugeleza kwegazi kube yizinhlayiya zekhanda.

Imiphumela emibi ye-DHT blocker

Eminye imiphumela emibi ebhalwe phansi ye-DHT blockers ifaka:

• ukungasebenzi kahle kwe-erectile
• ukukhipha umjovo kusenesikhathi noma ukuthatha isikhathi eside ukukhipha umuthi
• ukukhula ngokweqile kwamafutha nobumnene obuzungeze indawo yebele
• ukuqubuka
• ngizizwa ngigula
• ukuhlanza
• ukufiphaza nokujiya kwezinwele zomzimba ebusweni nangaphezulu
• ukuminyaniswa kwenhliziyo okuvela osawoti noma ukugcinwa kwamanzi, ikakhulukazi nge-minoxidil

Ezinye izimbangela zokulahleka kwezinwele

I-DHT ayisona ukuphela kwesizathu sokuthi kungenzeka ukuthi ubona izinwele zakho zincipha noma ziwa. Nazi ezinye izizathu ezimbalwa okungenzeka ukuthi ulahlekelwa yizinwele zakho.

I-Alopecia areata

I-Alopecia areata yisimo sokuzimela lapho umzimba wakho uhlasela izintambo zezinwele ekhanda lakho nakwezinye izindawo emzimbeni wakho.

Yize ungaqaphela amabala amancane ezinwele ezilahlekile ekuqaleni, lesi simo ekugcineni singadala impandla ephelele ekhanda lakho, kumashiya, ezinweleni ebusweni nasezinwele zomzimba.

I-lichen planus

I-lichen planus ngesinye isimo sokuzilimaza esibangela ukuthi umzimba wakho uhlasele amaseli akho esikhumba, kufaka phakathi lawo asekhanda lakho. Lokhu kungaholela ekulimaleni kwesikhumba okwenza izinwele zakho ziphume.

Izimo ze-thyroid

Izimo ezibangela ukuthi indlala yakho yegilo ikhiqize kakhulu (i-hyperthyroidism) noma incane kakhulu (i-hypothyroidism) yamahomoni athile we-thyroid asiza ukulawula imetabolism yakho ingaholela ekulahlekelweni izinwele ekhanda.

Isifo seCeliac

Isifo seCeliac yisimo sokuzilimaza esibangela ukungasebenzi kahle kokugaya ukudla ekuphenduleni ukudla i-gluten, iphrotheni evame ukutholakala ekudleni okufana nesinkwa, i-oats, nokunye okusanhlamvu. Ukulahleka kwezinwele kuyisibonakaliso salesi simo.

Ukutheleleka kwesikhumba

Izimo ezahlukahlukene zekhanda, ikakhulukazi izifo zokukhunta ezifana ne-tinea capitis - nayo ebizwa ngokuthi umbandamu wesikhumba - ingenza isikhumba sakho sikhanye futhi sicasuke, kubangele ukuthi izinwele ziphume ezinhlakeni ezinegciwane.

Izinwele zoqalo

Izinwele zoqalo zenzeka lapho imicu yakho ethile yezinwele ibukeka izacile, ifindo, futhi ihlukaniswe, kunokuba bushelelezi. Kuyisibonakaliso esivamile sesimo esaziwa nge-Netherton syndrome, isifo sofuzo esiholela ekuchithekeni kwesikhumba ngokweqile nokukhula kwezinwele ngendlela engajwayelekile.

Ukudla okudlela endlini

I-DHT yaziwa kakhulu, iyimbangela enkulu yokulahleka kwezinwele zamaphethini wesilisa okuxhunyaniswe nakho kokubili ukuthambekela kwezakhi zofuzo ekulahlekelweni izinwele kanye nezinqubo zemvelo emzimbeni wakho ezikwenza ulahlekelwe yizinwele njengoba ukhula.

Kuningi ukwelashwa kokulahleka kwezinwele okukhuluma nge-DHT okutholakalayo, futhi ukunciphisa ukulahleka kwezinwele kungakwenza uzizwe uzethemba ngokwengeziwe ngokubukeka kwakho empilweni yakho yansuku zonke. Kepha khuluma nodokotela kuqala, ngoba akuyona yonke imishanguzo engaphepha noma isebenze kuwe.