I-Cholinesterase - igazi

I-serum cholinesterase ukuhlolwa kwegazi okubheka amazinga ezinto ezimbili ezisiza uhlelo lwezinzwa ukuthi lusebenze kahle. Babizwa nge-acetylcholinesterase ne-pseudocholinesterase. Izinzwa zakho zidinga lezi zinto ukuthumela amasiginali.

I-Acetylcholinesterase itholakala kwizicubu zomzimba namaseli abomvu egazi. I-Pseudocholinesterase itholakala ngokuyinhloko esibindini.

Kudingeka isampula yegazi. Isikhathi esiningi igazi likhishwa emthanjeni ongaphakathi endololwaneni noma ngemuva kwesandla.

Azikho izinyathelo ezikhethekile ezidingekayo ukulungiselela lolu vivinyo.

Ungase uzwe ubuhlungu obuncane noma isitinyela lapho kufakwa inaliti. Ungase futhi uzizwe ushaywa yisiza ngemuva kokukhishwa kwegazi.

Umhlinzeki wakho wezokunakekelwa kwempilo anga-oda lokhu kuhlolwa uma kungenzeka uvezwe amakhemikhali abizwa nge-organophosphates. Lawa makhemikhali asetshenziswa emithini yokubulala izinambuzane. Lokhu kuhlolwa kungasiza ekutholeni ubungozi bakho bokufakwa ubuthi.

Ngaphansi kakhulu, lokhu kuhlolwa kungenziwa:

• Ukuhlonza isifo sesibindi
• Ngaphambi kokuthola i-anesthesia nge-succinylcholine, enganikezwa ngaphambi kwezinqubo noma izindlela ezithile zokwelashwa, kufaka phakathi i-electroconvulsive therapy (ECT)

Imvamisa, amanani we-pseudocholinesterase ajwayelekile aphakathi kwamayunithi ayi-8 no-18 ngemililitha (U / mL) noma amakhilogremu ayi-8 nangu-18 ngelitha ngalinye (kU / L)

Qaphela: Amabanga wamanani ajwayelekile angahluka kancane kumalabhorethri ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ukwehla kwamazinga we-pseudocholinesterase kungahle kube ngenxa:

• Ukutheleleka okungamahlalakhona
• Ukungondleki okungapheli
• Isifo senhliziyo
• Ukulimala kwesibindi
• I-Metastasis
• I-jaundice evimbelayo
• Ubuthi obuvela ku-organophosphates (amakhemikhali atholakala kuma-pesticides)
• Ukuvuvukala okuhambisana nezinye izifo

Ukwehla okuncane kungenzeka kungenxa yokuthi:

• Ukukhulelwa
• Ukusetshenziswa kwamaphilisi okulawula inzalo

I-Acetylcholinesterase; I-RBC (noma i-erythrocyte) cholinesterase; I-Pseudocholinesterase; I-Plasma cholinesterase; I-Butyrylcholinesterase; I-serum cholinesterase

• Ukuhlolwa kweCholinesterase

U-Aminoff MJ, ngakho-ke YT. Imiphumela yama-toxin kanye nama-ejenti womzimba ohlelweni lwezinzwa. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 86.

UNelson LS, Ford MD. Ubuthi obunzima. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 110.