Izifo Zokuqala Zika-Alzheimer's

-Delile

• Izimbangela zokuqala i-Alzheimer's
• Izakhi zofuzo ezinqumayo
• Izakhi zofuzo zobungozi
• Izimpawu zokuqala kwesifo i-Alzheimer's
• Yikuphi ukuhlolwa okuzokwenziwa udokotela wakho ukuthola i-Alzheimer's?
• Ukucatshangelwa kokuhlolwa kofuzo
• Thola ukwelashwa kusenesikhathi
• Ukuphila ekuqaleni kwesifo i-Alzheimer's
• Usizo kulabo abanesifo sokuqala se-Alzheimer

Isifo sofuzo sihlasela abasha

Abantu abangaphezu kwezigidi ezi-5 e-United States baphila nesifo i-Alzheimer's. Isifo i-Alzheimer yisifo sobuchopho esithinta ikhono lakho lokucabanga nokukhumbula. Kuyaziwa njengokuqala kwe-Alzheimer's, noma i-Alzheimer's's early, lapho kwenzeka kumuntu ngaphambi kokuba afinyelele eminyakeni yobudala engama-65.

Akuvamile ukuthi i-Alzheimer's's early iqale ukukhula kubantu abakwiminyaka yama-30 noma 40. Ngokuvamile kuthinta abantu abaseminyakeni yabo-50. Abantu abalinganiselwa ku-5% abanesifo i-Alzheimer's bazoba nezimpawu zokuqala kwe-Alzheimer's. Funda kabanzi ngezici zobungozi kanye nokuthuthuka kokuqala kwe-Alzheimer's nokuthi ungasingatha kanjani ukuxilongwa.

Izimbangela zokuqala i-Alzheimer's

Iningi labantu abasha elitholwe linesifo i-Alzheimer ekuqaleni kwesifo linenkinga ngaphandle kwesizathu esaziwayo. Kodwa abanye abantu abahlangabezana nesifo i-Alzheimer ekuqaleni kwesikhathi banesimo ngenxa yezimbangela zofuzo. Abaphenyi bakwazile ukukhomba izakhi zofuzo ezinquma noma ezandisa ubungozi bokuthuthukisa i-Alzheimer's.

Izakhi zofuzo ezinqumayo

Enye yezimbangela zofuzo “izakhi zofuzo ezinqumayo.” Izakhi zofuzo ezinqumayo ziqinisekisa ukuthi umuntu uzoba nenkinga. Lezi zofuzo zibalwa ngaphansi kwamaphesenti ama-5 amacala e-Alzheimer.

Kunezakhi zofuzo ezintathu ezingavamile ezibangela ukuqala kwesifo i-Alzheimer's:

• I-Amyloid precursor protein (APP): Le protein yatholakala ngo-1987 futhi itholakala kuma-chromosomes angama-21. Inikeza iziyalezo zokwenza iprotheni etholakala ebuchosheni, emgogodleni nakwezinye izicubu.
• I-Presenilin-1 (PS1): Ososayensi bakhomba le geni ngo-1992. Itholakala kumbhangqwana we-14 we-chromosome. Ukwehluka kwe- PS1 yizimbangela ezivame kakhulu ze-Alzheimer's.
• I-Presenilin-2 (PS2) Lokhu kungukuguqulwa kwesithathu kofuzo okutholwe kubanga i-Alzheimer's. Itholakala kubhangqa lokuqala le-chromosome futhi yahlonzwa ngo-1993.

Izakhi zofuzo zobungozi

Izakhi zofuzo ezintathu zokunquma ziyehluka kwe-apolipoprotein E (APOE-e4). APOE-e4 ​​Isakhi sofuzo esaziwa ukukhulisa ubungozi bakho be-Alzheimer's futhi senze izimpawu zivele ngaphambili. Kodwa akuqinisekisi ukuthi othile uzoba nayo.

Ungazuza njengekhophi elilodwa noma amabili wefayela le- APOE-e4 ​​Isakhi. Amakhophi amabili aphakamisa ubungozi obukhulu kunelilodwa. Kulinganiselwa lokho APOE-e4 ​​cishe amaphesenti angama-20 kuya kwangu-25 amacala e-Alzheimer.

Izimpawu zokuqala kwesifo i-Alzheimer's

Iningi labantu libhekana nokuhluleka kwenkumbulo yesikhashana. Ukubeka okhiye ngokungafanele, ukungabi nalutho egameni lomuntu othile, noma ukukhohlwa isizathu sokuzulazula egumbini kuyizibonelo ezimbalwa. Lezi akuzona izimpawu ezicacile zokuqala i-Alzheimer's, kodwa ungahle uthande ukuqaphela lezi zimpawu nezimpawu uma unengozi yezofuzo.

Izimpawu zokuqala kwe-Alzheimer ziyefana nezinye izinhlobo ze-Alzheimer's. Izimpawu nezimpawu okufanele uziqaphele zifaka:

• kunzima ukulandela iresiphi
• kunzima ukukhuluma noma ukugwinya
• ukubeka izinto ngokungajwayelekile kahle ngaphandle kokukwazi ukubuyisa izinyathelo zokuzithola
• ukungakwazi ukulinganisela i-akhawunti yokuhlola (ngale kwephutha lezibalo elenziwa ngezikhathi ezithile)
• ukulahleka endleleni eya endaweni ejwayelekile
• ukulahlekelwa ithrekhi yosuku, usuku, isikhathi, noma unyaka
• ukuguquka kwemizwelo nobuntu
• inkathazo ngokubona okujulile noma izinkinga zombono ongazelelwe
• ukuhoxa emsebenzini nakwezinye izimo zenhlalo

Uma ungaphansi kweminyaka engama-65 futhi uhlangabezana nalezi zinguquko, khuluma nodokotela wakho.

Yikuphi ukuhlolwa okuzokwenziwa udokotela wakho ukuthola i-Alzheimer's?

Akukho sivivinyo esisodwa esingaqinisekisa ukuqala kwe-Alzheimer's's early. Xhumana nodokotela onolwazi uma unomlando womndeni wokuqala kwe-Alzheimer's.

Bazothatha umlando ophelele wezokwelapha, benze ukuhlolwa okuningiliziwe kwezokwelapha nezinzwa, futhi babuyekeze izimpawu zakho. Ezinye izimpawu zingabonakala ngathi:

• ukukhathazeka
• ukudana
• ukusetshenziswa kotshwala
• imiphumela emibi yemithi

Inqubo yokuxilonga ingafaka futhi i-magnetic resonance imaging (MRI) noma i-computed tomography (CT) yokuskena kobuchopho. Kungase kube nokuhlolwa kwegazi ukukhipha ezinye izifo.

Udokotela wakho uzokwazi ukunquma ukuthi ngabe uqale yini ukuqala kwe-Alzheimer ngemuva kokukhipha ezinye izimo.

Ukucatshangelwa kokuhlolwa kofuzo

Ungahle uthande ukubonisana nomeluleki wezofuzo uma unengane yakini, umzali, noma ugogo noma umkhulu owakhula i-Alzheimer ngaphambi kweminyaka yobudala engama-65. Ukuhlolwa kofuzo kubheka ukubona ukuthi uphethe yini izakhi zofuzo zokunquma noma ezinobungozi ezibangela ukuqala kwe-Alzheimer's.

Isinqumo sokuthola lolu vivinyo esomuntu siqu. Abanye abantu bakhetha ukufunda ukuthi banezakhi zofuzo okufanele bazilungiselele ngangokunokwenzeka.

Thola ukwelashwa kusenesikhathi

Ungalibali ukukhuluma nodokotela wakho uma ungahle ube khona ekuqaleni kwe-Alzheimer's. Yize lungekho ikhambi lalesi sifo, ukusithola kusenesikhathi kungasiza ngemithi ethile nangokulawula izimpawu. Le mithi ihlanganisa:

• I-donepezil (i-Aricept)
• I-rivastigmine (Exelon)
• i-galantamine (Razadyne)
• i-memantine (Namenda)

Ezinye izindlela zokwelapha ezingasiza ekuqaleni kwe-Alzheimer's zihlanganisa:

• ukuhlala usebenza
• ukuqeqeshwa kwengqondo
• amakhambi nezithako
• ukunciphisa ukucindezeleka

Ukugcina uxhumekile nabangane nomndeni ukuze uthole ukusekelwa nakho kubaluleke kakhulu.

Ukuphila ekuqaleni kwesifo i-Alzheimer's

Lapho abantu abasha befika esigabeni esidinga ukunakekelwa okwengeziwe, lokhu kungadala isithombe sokuthi isifo sesihambe ngokushesha okukhulu. Kepha abantu abanesifo sokuqala i-Alzheimer's's abaqhubeki ngokushesha ngezigaba. Iqhubeka phakathi neminyaka eminingana kubantu abasha njengoba yenza kubantu abadala abaneminyaka engaphezu kwengama-65.

Kodwa kubalulekile ukuhlela kusengaphambili ngemuva kokuthola ukuxilongwa. Ukuqala kokuqala kwe-Alzheimer kungathinta izinhlelo zakho zezezimali nezomthetho.

Izibonelo zezinyathelo ezithile ezingasiza ukufaka:

• ukufuna iqembu lokusekela labo abane-Alzheimer's
• ukuncika kubangani nomndeni ukuthola ukusekelwa
• ukuxoxa ngendima yakho, nokutholakala komshuwalense wokukhubazeka, nomqashi wakho
• ukudlula umshwalense wezempilo ukuqinisekisa ukuthi imishanguzo ethile nokwelashwa kuyambozwa
• ukuba namaphepha omshwalense wokukhubazeka ngendlela ngaphambi kokuba kuvele izimpawu
• ukuzibandakanya ekuhleleni kwezezimali ngekusasa uma impilo yomuntu iguquka ngokuzumayo

Ungesabi ukufuna usizo kwabanye phakathi kwalezi zinyathelo. Ukulungisa izindaba zakho siqu kunganikeza ukuthula kwengqondo njengoba uhamba ngezinyathelo zakho ezilandelayo.

Usizo kulabo abanesifo sokuqala se-Alzheimer

Okwamanje alikho ikhambi lesifo i-Alzheimer's. Kepha kunezindlela zokuphatha lesi simo ngokwezempilo futhi uphile impilo enempilo ngangokunokwenzeka. Izibonelo zezindlela ongahlala ngazo kahle ekuqaleni kwesifo se-Alzheimer zifaka:

• ukudla ukudla okunempilo
• ukunciphisa ukuphuza utshwala noma ukuqeda ngokuphelele utshwala
• ukuzibandakanya kumasu okuphumula ukunciphisa ingcindezi
• ukufinyelela ezinhlanganweni ezinjenge-Alzheimer's Association ukuthola ulwazi ngamaqembu okusekela kanye nezifundo ezingaba khona zocwaningo

Abaphenyi bafunda kabanzi ngalesi sifo nsuku zonke.