Umlobi: Lewis Jackson
Usuku Lokudalwa: 9 Mhlawumbe 2021
Ukuvuselela Usuku: 11 Ufebhuwari 2025
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-Delile

I-Gout uhlobo oluvamile lwe-arthritis. Ukuvuvukala okungazelelwe futhi okubuhlungu okuvamise ukwenzeka kuzwane olukhulu, kodwa kungathinta amanye amalunga. Imahlombe nasezinqeni.

Ukuvuvukala kubangelwa ukwakheka kwamakristalu amancane e-uric acid emajoyini akho naseduze kwawo. Amasosha akho omzimba aphendula ngokuthumela amangqamuzana alwa nokutheleleka endaweni, abangele ukuvuvukala.

Ukuhlaselwa yi-Gout kuvamise ukuba khona ngezikhathi ezithile futhi kungathinta amalunga angaphezu kwelilodwa. I-Gout imvamisa ingalawulwa ngokudla nangemithi. Lapho i-gout ilashwa, izinkinga ziyaqabukela. Kepha i-gout engalashwa ingakhubaza.

Kukhona ukuthi abanye abantu banokuthambekela kofuzo ku-gout.

Amaqiniso asheshayo mayelana ne- gout

  • Incazelo yegawuthi ihlehlela emuva eminyakeni ecishe ibe ngu-5 000 iye eGibhithe lasendulo. Kuthathwa njengohlobo oluqondakala kahle kunazo zonke lwe-arthritis.
  • Mayelana nomphakathi womhlaba wonke une-gout.
  • Abantu abangamaphesenti amane e-United States bane-gout.
  • Isimo se-gout besilokhu sikhula eminyakeni yamuva emazweni athuthukile.
  • Igama livela egameni lesiLatini elithi "gutta," elisho ukuwa. Kubhekiswe enkolelweni yangezikhathi eziphakathi yokuthi enye yalezi “zimnandi” ezidingekayo ukuze impilo “yehle” ilunga.
  • UGout wabizwa ngesifo samakhosi, ngenxa yokuhlangana kwayo nokudla okunothile nokuphuza utshwala.
  • UBenjamin Franklin noThomas Jefferson bobabili babene-gout.

Izimpawu ze-gout ehlombe lakho

Ukuhlaselwa yi-Gout kuvame ukufika ngokuzumayo. Ubuhlungu bakho behlombe mhlawumbe bunzima noma buhlungu.


Ngaphezu kwalokho, indawo ingahle ibe:

  • okubomvu
  • kuvuvukele
  • aqinile
  • kushisa noma kuyasha
  • izwela kakhulu ukuthinta nokunyakaza

Izimbangela ze-gout ehlombe lakho

I-uric acid eyeqile egazini lakho kucatshangwa ukuthi ingadala i-gout ngokwakha amakristalu amise okwenaliti akha ezicutshini nasemalungeni akho. I-uric acid eyeqile yaziwa njenge-hyperuricemia.

I-Uric acid ingumkhiqizo wemfucuza okhiqizwa ukuwohloka kwama-purines, amakhemikhali amakhemikhali akhona ngokwemvelo emzimbeni wakho. I-Uric acid nayo ikhiqizwa uma ugaya ukudla okuqukethe ama-purines.

Imvamisa izinso zakho zisusa imfucuza ye-uric acid ngomchamo wakho. Uma izinso zakho zingasebenzi kahle, amazinga e-uric acid angakha egazini lakho.

Amakristalu akha le uric acid eyeqile ahlaselwa amasosha akho omzimba njengemizimba yangaphandle. Amaseli alwa nezifo aya endaweni yamakristalu, abangele ukuvuvukala.

I-gout ibika ukuthi amaphesenti ayi-10 kuphela amacala abangelwa ukukhuphuka komzimba wakho we-uric acid. Amanye amaphesenti angama-90 adalwa ukwehluleka kwezinso ukukhipha i-uric acid eyanele.


Ukukhiqizwa ngokweqile kwe-uric acid

Ukudla imikhiqizo eyeqile equkethe ama-purine kungahle kube nomthelela kumazinga we-uric acid ngokweqile kwabanye abantu. Imikhiqizo ephezulu yama-purines ifaka phakathi:

  • inyama ebomvu
  • ukudla kwasolwandle
  • inhlanzi
  • ubhiya
  • ubhontshisi omisiwe

Utshwala, ikakhulukazi utshwala obunobufakazi obuphezulu, futhi bukhuthaza ukukhiqizwa nokugcinwa kwe-uric acid. Kodwa ukuphuza iwayini ngamanani alinganiselayo akuhlotshaniswa ne-gout.

Ezinye izinto

Kuphela cishe ngamazinga aphezulu e-uric acid egazini lawo aqala i-gout. Ezinye izinto ezingabandakanyeka ekwakhiweni kwe-gout zifaka:

  • ukuthambekela kofuzo
  • ukuphazamiseka kwegazi
  • umdlavuza onjenge-leukemia
  • i-synovial fluid encane kakhulu emajoyintini
  • i-asidi yoketshezi oluhlangene
  • ukudla okunama-purines amaningi
  • ukulimala ngokuhlanganyela, ukutheleleka, noma ukuhlinzwa
  • izimo eziphezulu zenzuzo yamaseli njenge-psoriasis

Imithi ethile ingakhuphula amazinga e-uric acid egazini. Lokhu kufaka phakathi:


  • isisu, esetshenziselwa ukwelapha umfutho wegazi ophakeme noma isifo senhliziyo
  • imithamo ephansi ye-aspirin
  • cyclosporine, umuthi ocindezela amasosha omzimba
  • i-levodopa, umuthi osetshenziselwa ukwelapha i-Parkinson's

Izici zobungozi bokuguliswa ehlombe lakho

Noma isiphi isici esikhuphula amazinga e-uric acid egazini lakho singakubeka engcupheni yokuthola i-gout. Ezinye zezici ezithile zobungozi yilezi:

Ubulili

I-Gout icishe ivame kakhulu emadodeni.

Ubudala

I-Gout ivame ukuvela emadodeni angaphezu kwama-40 nakwabesifazane ngemuva kokunqamuka kokuya esikhathini. Ngo, ukwanda kwe-gout cishe kungamaphesenti ayi-10 abesilisa namaphesenti ama-6 abesifazane.

Izakhi zofuzo

Ukuba namanye amalungu omndeni ane-gout kwandisa ingozi yakho. Kukhonjwe izakhi zofuzo ezithile ezihambisana namandla ezinso okususa i-uric acid.

Izimo zezokwelapha

Izimo zezempilo ezithinta ukusebenza kwezinso zikubeka engcupheni yokutholwa yi-gout. Uma uhlinzwa noma uhlukumezeka, lokhu kungakhuphula ubungozi bakho.

Abantu abaningi abane-gout nabo banezinye izimo zezokwelapha. Ukuthi i-gout idala lezi zimo noma inyusa ingozi yalezi zimo akucaci.

Ezinye zezimo zezokwelapha ezikhulisa ubungozi bakho bokungenwa yi-gout, ikakhulukazi uma zingelashwa, zifaka:

  • umfutho wegazi ophakeme
  • isifo sikashukela
  • isifo sezinso
  • ezinye izinhlobo ze-anemia
  • isifo se-metabolic syndrome
  • ukuvimbela ukuphefumula kokulala
  • ukhwekhwe
  • ukuhola ubuthi

Indlela Yokuphila

Ukukhuluphala ngokweqile noma ukukhuluphala ngokweqile kwandisa amathuba okuba ne-gout. Isisindo esengeziwe sandisa ukukhiqizwa kwakho kwe-uric acid.

Ukudla ukudla okweqile neziphuzo eziphakeme kuma-purine kungakhuphula ingozi yokuba ne-gout. Labo abadla ukudla okususelwa kwilayisi nemifino kanye ne-purine ephansi banezifo eziphansi ze-gout.

Ukuxilongwa kwe-gout ehlombe lakho

Udokotela wakho uzokuhlola, athathe umlando wezokwelapha, abuze ngezimpawu zakho. Bangakwazi ukubona i-gout ngokuya ngezimpawu zakho.

Kepha udokotela uzofuna ukukhipha ezinye izimbangela zobuhlungu behlombe lakho ngoku-oda izivivinyo.

Ukuhlola ukuhlolwa kwehlombe lakho kufaka phakathi i-X-ray, i-ultrasound, ne-MRI scan.

Udokotela futhi uzohlola amazinga egazi e-uric acid. Kodwa amazinga aphezulu noma i-uric acid akwanele ukwenza ukuxilongwa okucacile.

Ukuhlolwa okuningiliziwe ukuthatha isampula lehlombe lakho elihlangene le-synovial fluid usebenzisa inaliti ezacile. Lokhu kubizwa ngokuthi i-arthrocentesis noma isifiso esihlangene. Ilabhorethri izobe isibheka amakristalu e-uric acid ngaphansi kwesibonakhulu.

Udokotela wakho angakudlulisela ku-rheumatologist ukuze uthole ukwelashwa okuqhubekayo.

Ukwelashwa kwe-gout ehlombe lakho

Alikho ikhambi le-gout, kepha imishanguzo eminingi isungulwe eminyakeni yamuva engasiza ngobuhlungu behlombe lokuqhuma nokuvimbela ukuqhuma kwesikhathi esizayo.

Imithi ihlose ukunciphisa izinhlungu, yehlise amazinga akho e-uric acid, futhi yehlise ukuvuvukala.

Imithi ejwayelekile

Udokotela wakho angase asikisele izidakamizwa ezingekho emthethweni ze-nonsteroidal anti-inflammatory (NSAIDs) zezinhlungu noma imishanguzo kadokotela eyehlisa ukuvuvukala.

Imithi kadokotela ifaka i-indomethacin (Indocin) noma i-celecoxib (i-Celebrex), ne-prednisone, i-corticosteroid. I-Prednisone ivame ukujojelwa ejoyintini elithintekile, kepha i-prednisone yomlomo ingadinga lapho amalunga amaningi ehilelekile.

Ngokuya ngobukhulu bezimpawu zakho, udokotela wakho angakunikeza ezinye izidakamizwa:

  • vimbela amaseli egazi amhlophe ekuhlaseleni amakristalu e-uric acid, afana ne-colchicine (Colcrys)
  • ukunciphisa inani lokukhiqizwa kwe-uric acid, njenge-allopurinol (iZyloprim) ne-febuxostat (Uloric), okuthiwa yi-xanthine oxidase inhibitors
  • siza izinso zakho zisuse i-uric acid eningi, njenge-probenecid (Probalan) ne-lesinurad (i-Zurampic), ebizwa nge-uricosurics

Yonke le mithi inemiphumela engemihle, kanti eminye ingaxhumana neminye imithi noma yenze ezinye izimo zibe zimbi kakhulu. Qiniseka ukuthi uxoxa nodokotela wakho ngohlelo lwakho lokwelashwa kwezidakamizwa.

Ezinye izidakamizwa

futhi ungathola isilingo somtholampilo.

Udokotela wakho futhi angafuna ukuzama ukusebenzisa umuthi omusha “off label,” noma ngenhloso engavunyelwe okwamanje.

Uma umuthi uvunyelwe i-rheumatoid arthritis noma esinye isimo futhi ungakavunyelwa i-gout, udokotela wakho angakuncoma ukuthi kungabikho ilebula.

Eminye yale mithi emisha yile:

  • i-pegloticase (i-Krystexxa), eyehlisa i-uric acid futhi yamukelwa e-United States ukuze yelashwe i-gout chronic refractory chronic
  • canakinumab, i-anti-monoclonal antibody ecindezela ukuvuvukala
  • anakinra, i-interleukin-1 beta antagonist ecindezela ukuvuvukala

Kungase kudingeke ukuthi ubuze nomhlinzeki wakho womshuwalense ukuthola le mithi uma isetshenziswa ngaphandle kwelebula.

Okunye ukwelashwa

Ubufakazi obuphathelene nezinguquko ekudleni abuhambisani, ngokusho kwe-American College of Physicians ye-gout ngo-2017.

Ucwaningo lukhombisile ukuthi ukuncishiswa kokudla kwenyama ebomvu, ushukela, notshwala kunciphise amazinga e-uric acid. Kepha bekungacaci ukuthi lokhu kuthuthukise imiphumela yezimpawu.

Ungathola ukukhululeka kwezinye izindlela zokwelapha ukuvuvukala, njengeqhwa nokwelashwa komzimba.

Isikhathi se-gout flare-up

Ukuqubuka kokuqala kwe-gout kuvame ukuhlala. Umzimba uvala impendulo yokuvuvukala ngemuva kwesikhathi esithile.

Ungahle uthole ukugqashuka okuphindiwe ezinyangeni eziyisithupha kuya eminyakeni emibili, noma nganoma isiphi isikhathi esizayo uma izinto ezinobungozi zingashintshi. I-Gout ingaba yisifo esingelapheki, ikakhulukazi uma uqhubeka nokuba namazinga aphezulu e-uric acid.

I-Gout nayo ingasakazeka ifake amanye amalunga. I-shoulder gout ingenzeka kubantu abane-gout enamandla ende.

Udokotela wakho angakunika amazinga aphansi emithi njalo ukuze asize ekuvikeleni ukuqubuka kwesikhathi esizayo kanye nezinkinga ezikhona, nokunciphisa izinga le-uric acid serum. Kubalulekile ukunamathela ohlelweni lwakho lokwelashwa ukunciphisa ama-flare.

Izinkinga ze-gout ehlombe lakho

Abantu abane-gout yesikhathi eside engapheli bangaba nezinkinga. Amakhemikhali e-Uric acid ngokuhamba kwesikhathi angalimaza ihlombe noma amanye amalunga.

Cishe amaphesenti ayi-15 abantu abane-gout bakha amatshe ezinso njengoba i-uric acid iqoqana ezinso.

Enye inkinga ye-gout engapheli ukwakhiwa kwamaqhuqhuva e-uric acid ezicutshini zakho ezithambile, ikakhulukazi iminwe yakho nezinzwani. I-nodule ibizwa nge-tophus.

La maqhuqhuva awavamile ukuba buhlungu, kodwa angavuvuka, angenwe igciwane, noma abe ne-oozy. La maqhuqhuva angancibilika ngokwelashwa okufanele kwemithi.

Ukuvimbela i-gout

Izindlela zokuvimbela i-Gout zifaka phakathi izindlela zokuphila ezilandelayo:

  • ukudla ukudla okunempilo, kufaka phakathi inani elilinganiselwe noma elilinganisiwe lokudla neziphuzo ezinama-purine amaningi
  • ukugcina isisindo esinempilo
  • ukuzivocavoca umzimba njalo
  • ukuphuza amanzi amaningi
  • ukuyeka ukubhema

Ungahle ufune ukulandela umkhondo walokho okubonakala kubangela ukuqhuma kwe-gout yakho yehlombe ukuze uvikele ukuqhuma kwesikhathi esizayo.

Ezinye izimo ezidala ubuhlungu behlombe nokuvuvukala

Uma unezinhlungu ehlombe nokuvuvukala, kungcono ukubona udokotela wakho ukuthola ukuxilongwa okuqondile nokwelashwa. Kunezivivinyo ezithile ezingakhomba i-gout.

Ezinye zezinye izimo ezingaba nezimpawu ezifanayo zifaka:

  • i-bursitis
  • i-tendinitis
  • Izinyembezi zemisipha
  • i-osteoarthritis

I-Pseudogout

Kukhona nohlobo lwe-arthritis olwaziwa nge-pseudogout, oluthinta ikakhulukazi abantu abadala asebekhulile. I-pseudogout ibangela ukuvuvukala okungazelelwe okubuhlungu emalungeni, kepha amakristalu e-uric acid awabandakanyeki. I-pseudogout ibangelwa ukuqongelela kwamakristalu we-calcium pyrophosphate dihydrate.

Ukuhlaziywa kwamakristalu ku-synovial fluid yakho kunganquma ukuthi ukuvuvukala kwehlombe lakho yi-pseudogout noma i-shoulder gout.

Umbono

I-Gout ehlombe yisimo esingajwayelekile, kepha ukwelashwa nokubukwa kuyefana nokuthola igciwane kwamanye amalunga. Ngazo zonke izinhlobo ze-gout, ukunamathela kumuthi wakho nakuhlelo lokwelashwa kuzokunikeza umphumela ongcono.

Kubalulekile ukubona udokotela uma unesifo sokuvuvukala ehlombe nobuhlungu. Uma kuyi-gout, ukwelashwa kuzokusiza ukuphatha lesi simo futhi kusize ekuvikeleni ukuqubuka kwesikhathi esizayo. Udokotela wakho angakweluleka ngezindlela zokwelashwa ezintsha ezisakhiwa.

Ungahle uthande ukuxhumana ne-Alliance for Gout Awareness noma i-Arthritis Foundation ukuze uhambisane nentuthuko entsha ekwelashweni kwe-gout.

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