Yini iMalignant Hyperthermia futhi ukwelashwa kwenziwa kanjani?

-Delile

• Izimbangela ezingaba khona
• Ziyini izimpawu
• Yelashwa kanjani

I-hyperthermia ebulalayo iqukethe ukwanda okungalawuleki kokushisa komzimba, okudlula amandla omzimba okulahlekelwa ukushisa, kungabikho ushintsho ekulungisweni kwesikhungo se-hypothalamic thermoregulatory, okuvame ukwenzeka ezimeni zomkhuhlane.

I-hyperthermia ebulalayo ingenzeka kubantu abanokungafani okuzuze njengefa emisipheni yamathambo futhi abachayeke kuma-anesthetics ahogelwayo, njenge-halothane noma i-enflurane, ngokwesibonelo futhi nangemva kokuchayeka ku-relaxant yemisipha ebizwa ngokuthi i-succinylcholine.

Ukwelashwa kuqukethe ukupholisa umzimba nokufaka imishanguzo emthanjeni, okufanele kwenziwe ngokushesha okukhulu, ngoba i-hyperthermia ebulalayo ingabulala.

Izimbangela ezingaba khona

I-hyperthermia ebulalayo ibangelwa ukungafani kwefa okwenzeka ku-sarcoplasmic reticulum yemisipha yamathambo, edala ukwanda okusheshayo kwenani le-calcium ngaphakathi kwamaseli, ekuphenduleni ukuphathwa kwe-anesthetics ehogelwayo, njenge-halothane noma i-enflurane, isibonelo, noma ukuvezwa ngenxa ye-succinylcholine muscle relaxant.

Thola ukuthi i-anesthesia isebenza kanjani nokuthi iziphi izingozi.

Lokhu kuphakama kwe-calcium emisipheni yamathambo kuholela ekwakhiweni kwesivumelwano sehaba semisipha, okwenza ukwanda okungazelelwe kokushisa.

Ziyini izimpawu

Izimpawu ze-hyperthermia ebulalayo zivame ukwenzeka ngesikhathi sokuchayeka ku-anesthesia futhi ukushisa okuphezulu, ukukhuphuka kwenhliziyo nokuqina kwemisipha, ukuqina kwemisipha nokulimala, i-acidosis nokungazinzi kwemisipha.

Yelashwa kanjani

I-hyperthermia ebulalayo kufanele ilashwe ngokushesha ngokuphazamisa i-anesthesia kanye nokuphathwa emthanjeni we-dantrolene sodium, isikhathi esingamahora angama-24 kuye kwangama-48, kuze kube yilapho umuntu engasebenzisa lesi sidakamizwa ngomlomo, uma kusadingeka.

Ngaphezu kokuphathwa kwalo muthi, umzimba womuntu ungapholiswa ngezipanji ezimanzi, amafeni noma izindawo zokugeza zeqhwa futhi, uma lezi zindlela zokupholisa zangaphandle zinganele, umzimba ungapholiswa nangaphakathi ngokuhlanzwa kwesisu nge-serum.

Ezimweni ezinzima kakhulu, lapho izinga lokushisa lingenakwehliswa ngokwanele, i-hemodialysis noma i-cardiopulmonary bypass nokupholisa igazi kungadingeka.