Qonda ukuthi yini i-Hypophosphatasia

-Delile

• Izinguquko ezinkulu ezibangelwa yi-Hypophosphatasia
• Izinhlobo ze-Hypophosphatasia
• Izimbangela ze-Hypophosphatasia
• Ukuxilongwa kwe-Hypophosphatasia
• Ukwelashwa kwe-Hypophosphatasia

I-Hypophosphatasia isifo esingajwayelekile sezakhi zofuzo esithinta izingane ikakhulukazi, esidala ukukhubazeka nokuqhekeka kwezinye izingxenye zomzimba kanye nokulahleka ngaphambi kwesikhathi kwamazinyo ezingane.

Lesi sifo sidluliselwa ezinganeni ngesimo sefa futhi asinakho ukwelashwa, ngoba kungumphumela wezinguquko zofuzo ezihlobene nokubalwa kwamathambo nokukhula kwamazinyo, kuphazamisa ukumuncwa kwamathambo.

Izinguquko ezinkulu ezibangelwa yi-Hypophosphatasia

I-Hypophosphatasia ingadala ushintsho oluningi emzimbeni olufaka:

• Ukuvela kokukhubazeka emzimbeni okufana nogebhezi olwandisiwe, amalunga akhulisiwe noma ukwehla komzimba;
• Ukubukeka kokuqhekeka ezifundeni eziningana;
• Ukulahlekelwa ngaphambi kwesikhathi kwamazinyo ezingane;
• Ubuthakathaka bemisipha;
• Kunzima ukuphefumula noma ukukhuluma;
• Ubukhona bamazinga aphezulu e-phosphate ne-calcium egazini.

Ezimweni ezimbi kakhulu zalesi sifo, zingavela kuphela izimpawu ezinomusa njengokuqhekeka noma ubuthakathaka bemisipha, okungadala ukuthi lesi sifo sitholakale lapho usumdala kuphela.

Izinhlobo ze-Hypophosphatasia

Kunezinhlobo ezahlukahlukene zalesi sifo, ezibandakanya:

• I-Perinatal hypophosphatasia - iyindlela ebucayi kakhulu yesifo evela ngokushesha ngemuva kokuzalwa noma lapho ingane isesibelethweni sikanina;
• I-hypophosphatasia yezinsana - ebonakala ngonyaka wokuqala wokuphila kwengane;
• I-juvenile hypophosphatasia - ebonakala ezinganeni noma kunini;
• I-hypophosphatasia yabantu abadala - ebonakala kuphela ebudaleni;
• i-odonto hypophosphatasia - lapho kukhona ukulahleka ngaphambi kwesikhathi kwamazinyo obisi.

Ezimweni ezinzima kakhulu, lesi sifo singadala nokufa kwengane nobukhulu bezimpawu buyehluka kuye ngomuntu kuye ngohlobo olukhonjisiwe.

Izimbangela ze-Hypophosphatasia

I-Hypophosphatasia ibangelwa ukuguqulwa noma izinguquko zofuzo ezihlobene nokubalwa kwamathambo nokukhula kwamazinyo. Ngale ndlela, kukhona ukunciphisa ukuncipha kwamathambo namazinyo. Ngokuya ngohlobo lwesifo, singaba namandla noma sibuyele emuva, sidluliselwe ezinganeni ngendlela yamafa ezakhi zofuzo.

Isibonelo, lapho lesi sifo sisebenza ngokweqile futhi uma bobabili abazali bephethe ikhophi eyodwa yokuguquka (banoguquko kodwa abangavezi izimpawu zesifo), kunamathuba angama-25% kuphela okuthi izingane zabo zihlakulele lesi sifo. Ngakolunye uhlangothi, uma lesi sifo sidlangile futhi uma kungumzali oyedwa kuphela onalesi sifo, kungaba nethuba elingu-50% noma elingu-100% lokuthi izingane nazo zizophatha.

Ukuxilongwa kwe-Hypophosphatasia

Endabeni ye-perinatal hypophosphatasia, lesi sifo singatholwa ngokwenza i-ultrasound, lapho kungatholwa khona ukukhubazeka emzimbeni.

Ngakolunye uhlangothi, esimweni se-Hypophosphatasia eseyinsana, esencane noma esikhulile, lesi sifo singatholakala ngama-radiographs lapho kutholakala khona izinguquko eziningana zamathambo ezibangelwa ukuntuleka kwamaminerali namathambo.

Ngaphezu kwalokho, ukuqedela ukuxilongwa kwalesi sifo, udokotela futhi angacela ukuhlolwa komchamo nokuhlolwa kwegazi, futhi kukhona nokwenzeka kokwenza ukuhlolwa kofuzo okukhomba ubukhona boshintsho.

Ukwelashwa kwe-Hypophosphatasia

Akukho muthi wokwelapha i-Hypophosphatasia, kepha okunye ukwelashwa okufana nePhysiotherapy ukulungisa ukuma komzimba nokuqinisa imisipha nokunakekelwa okwengeziwe ekuhlanzekeni ngomlomo kungakhonjiswa odokotela bezingane ukwenza ngcono impilo.

Izingane ezinale nkinga yezofuzo kufanele ziqashwe kusukela zizalwa futhi zilaliswe esibhedlela ngokuvamile kuyadingeka. Ukulandelwa kufanele kwandise impilo yonke, ukuze isimo sakho sempilo singahlolwa njalo.