U-Ilaris

-Delile

• Intengo
• Okukhonjiswe kona
• Isetshenziswa kanjani
• Imiphumela emibi engaba khona
• Ngubani ongafanele asebenzise

I-Ilaris ngumuthi olwa nokuvuvukala okhonjiswe ekwelapheni izifo ezivuthayo ze-autoimmune, njenge-multisystemic disease inflammatory noma i-juvenile idiopathic arthritis, isibonelo.

Isithako sayo esisebenzayo yi-canaquinumab, into evimbela ukusebenza kweprotheni ebalulekile ezinqubweni zokuvuvukala, ngakho-ke iyakwazi ukulawula nokunciphisa izimpawu zezifo ezivuthayo lapho kukhona khona ukukhiqizwa okwedlulele kwaleli protein.

I-Ilaris ngumuthi okhiqizwa ngamalabhorethri aseNovartis ongahlinzekwa kuphela esibhedlela ngakho-ke awutholakali emakhemisi.

Intengo

Ukwelashwa nge-Ilaris kunenani elilinganisiwe lama-reais ayizinkulungwane ezingama-60 ngesivalo ngasinye esingu-150 mg, noma kunjalo, ezimweni eziningi, ingatholakala mahhala nge-SUS.

Okukhonjiswe kona

I-Ilaris ikhonjisiwe ekwelapheni ama-syndromes ngezikhathi ahambisana ne-cryopyrin, kubantu abadala nasezinganeni, njenge:

• Isifo somzimba esivamile sokuvuvukala esibangelwa amakhaza, esibizwa nangokuthi i-urticaria ebandayo;
• Isifo seMuckle-Wells;
• Isifo sokuvuvukala kweMultisystemic ngokuqala kokubeletha, esaziwa nangokuthi yi-chronic-infantile-neurological-cutaneous-articular syndrome.

Ngaphezu kwalokho, lo muthi ungasetshenziselwa ukwelapha i-systemic juvenile idiopathic arthritis ezinganeni ezineminyaka engaphezu kwengu-2 ubudala, ezingazange zithole imiphumela emihle ngokwelashwa ngemithi engeyona i-steroidal anti-inflammatory kanye ne-systemic corticosteroids.

Isetshenziswa kanjani

I-Ilaris ijojowe kusendlalelo esinamafutha ngaphansi kwesikhumba futhi ingafakwa kuphela ngudokotela noma umhlengikazi esibhedlela. Umthamo kufanele uhambisane nenkinga nesisindo somuntu, futhi imihlahlandlela ejwayelekile yile:

• 50 mg weziguli ezingaphezu kwama-40 kg.
• 2 mg / kg yeziguli ezinesisindo esiphakathi kuka-15 kg no-40 kg.

Umjovo kufanele wenziwe njalo emavikini ayisishiyagalombili, ikakhulukazi ekwelapheni ama-syndromes ngezikhathi ezihambisana ne-cryopyrin, ngesikhathi esinconywe ngudokotela.

Imiphumela emibi engaba khona

Imiphumela emibi kakhulu yalo muthi ifaka imfiva, umphimbo obuhlungu, i-thrush, isiyezi, isiyezi, ukukhwehlela, ukuphefumula kanzima, ukuqaqamba noma izinhlungu zonyawo.

Ngubani ongafanele asebenzise

I-Ilaris akufanele isetshenziswe ezinganeni ezineminyaka engaphansi kwemibili noma kubantu abazwela kakhulu kunoma yiziphi izingxenye zayo ezisebenzayo. Ngaphezu kwalokho, kufanele isetshenziswe ngokuqapha ezigulini ezinezifo noma ezinokutheleleka kalula, njengoba lo muthi wandisa ubungozi bokutheleleka.