Ingabe i-Tylenol (i-Acetaminophen) i-Blood Thinner?

-Delile

• Isebenza kanjani iTylenol
• Izinzuzo zeTylenol
• Izithiyo zeTylenol
• I-Tylenol vs. ne-thinner yegazi
• Ukuphepha kokuthatha iTylenol enezici zegazi
• Ukukhetha isiqabu sobuhlungu
• Ukuthatha

I-Tylenol i-over-the-counter (OTC) yokunciphisa izinhlungu nokunciphisa imfiva lelo igama lomkhiqizo le-acetaminophen. Lo muthi uvame ukusetshenziswa kanye nezinye izinto zokunciphisa izinhlungu, njenge-aspirin, ibuprofen, ne-naproxen sodium.

Ngenkathi abanye abantu bethatha i-aspirin ngenxa yemiphumela yayo emincane yokuncipha kwegazi, iTylenol ayilona igazi elinciphile. Kodwa-ke, kusekhona izinto ezithile ezibalulekile okufanele uzazi ngeTylenol nokuthi isebenza kanjani lapho uthatha isinqumo phakathi kokuyisebenzisa nokunye okudambisa izinhlungu, kubandakanya nabanciphisi begazi.

Isebenza kanjani iTylenol

Yize i-acetaminophen ikhona iminyaka engaphezu kwekhulu, ososayensi abakabi namaphesenti ayi-100 ukuthi isebenza kanjani. Kunemibono eminingi yokusebenza.

Okunye okusakazeke kakhulu ukuthi isebenza ukuvimba izinhlobo ezithile zama-enzyme e-cyclooxygenase. La ma-enzyme asebenzela ukudala izithunywa zamakhemikhali ezibizwa ngokuthi ama-prostaglandin. Phakathi kweminye imisebenzi, ama-prostaglandin adlulisa imiyalezo ekhombisa ubuhlungu futhi iholele kumkhuhlane.

Ngokuqondile, i-acetaminophen ingamisa ukumiswa kwe-prostaglandin ohlelweni lwezinzwa. Ayivimbeli ama-prostaglandin kwezinye izicubu zomzimba eziningi. Lokhu kwenza i-acetaminophen yehluke ezidakamizweni ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen nayo ekhulula ukuvuvukala kwezicubu.

Yize lena kuyimbono edume kakhulu yokuthi iTylenol isebenza kanjani, abacwaningi bafunda nokuthi ingathinta kanjani ezinye izici zesistimu yezinzwa emaphakathi. Lokhu kufaka ama-receptors afana ne-serotonin ne-endocannabinoid.

Kungabonakala kungavamile ukuthi odokotela abazi kahle ukuthi iTylenol isebenza kanjani. Kodwa-ke, kunemithi eminingi etholakalayo emakethe yanamuhla enendaba efanayo ephephile uma isetshenziswa njengokuyalelwa.

Izinzuzo zeTylenol

I-Tylenol ikakhulu iyinhlungu ephephile futhi esebenzayo nokunciphisa imfiva. Ngoba odokotela bacabanga ukuthi iTylenol isebenza kakhulu ohlelweni lwezinzwa oluphakathi, mancane amathuba okuthi icasule isisu uma iqhathaniswa ne-aspirin ne-ibuprofen.

Futhi, iTylenol ayinayo imiphumela ekunqandeni igazi negazi njengoba kwenza i-aspirin. Lokhu kwenza kuphephe kubantu asebevele benciphisa igazi noma abasengozini yokopha.

Odokotela bavame ukuncoma iTylenol njengokudambisa izinhlungu lapho owesifazane ekhulelwe. Ukuthatha okunye ukudambisa izinhlungu, njenge-ibuprofen, kuhlotshaniswa nobungozi obukhulu bezinkinga zokukhulelwa kanye nezinkinga zokuzalwa.

Izithiyo zeTylenol

I-Tylenol ingalimaza isibindi sakho uma uyithatha kakhulu.

Uma uthatha iTylenol, umzimba wakho uyiphula iye enhlanganisweni ebizwa nge-N-acetyl-p-benzoquinone. Imvamisa, isibindi siphula le ngxube bese siyadedela. Kodwa-ke, uma kukhona okuningi okukhona, isibindi asikwazi ukusiphula futhi silimaze izicubu zesibindi.

Kungenzeka futhi ngengozi ukuthatha i-acetaminophen eningi kakhulu. I-acetaminophen etholakala eTylenol iyisengezo esivamile emithini eminingi. Lokhu kufaka phakathi imishanguzo yezinhlungu ze-narcotic nokunciphisa izinhlungu okungaqukatha i-caffeine noma ezinye izinto.

Umuntu angathatha isilinganiso esinconyiwe seTylenol futhi angazi ukuthi eminye imithi yakhe iqukethe i-acetaminophen. Yingakho kubalulekile ukuthi ufunde amalebula emithi ngokucophelela futhi njalo utshele udokotela wakho ngayo yonke imithi oyiphuzayo.

Futhi, kulabo abafisa ukuqeda izinhlungu okubuye kube nokuncipha kwegazi noma ukukhulula ukuvuvukala, iTylenol ayinikeli ngalokhu.

I-Tylenol vs. ne-thinner yegazi

Kokubili iTylenol ne-aspirin kungukunciphisa izinhlungu kwe-OTC. Kodwa-ke, ngokungafani neTylenol, i-aspirin nayo inezici ezithile ze-antiplatelet (clotting-blood).

I-aspirin ivimba ukwakheka kwenhlanganisela ebizwa nge-thromboxane A2 kuma-platelets egazini. Ama-platelet anesibopho sokunamathela ndawonye ukwakha ihlwili lapho usike noma unenxeba elopha.

Ngenkathi i-aspirin ingakuvimbeli ekunqandeni ngokuphelele (usazomisa ukopha lapho usikekile), yenza igazi lingabi manzi kakhulu. Lokhu kungasiza ekuvikeleni isifo sohlangothi nokuhlaselwa yinhliziyo okungabangelwa amahlule egazi.

Awukho umuthi ongaguqula imiphumela ye-aspirin. Isikhathi kuphela nokwakhiwa kwama-platelet amasha okungafeza lokhu.

Kubalulekile ukwazi ukuthi i-aspirin nayo iyatholakala kweminye imithi ye-OTC, kepha ayikhangiswa kahle. Izibonelo zifaka i-Alka-Seltzer ne-Excedrin. Ukufunda amalebula emithi ngokucophelela kungaqinisekisa ukuthi awuthathi ngephutha i-aspirin ngezindlela ezingaphezu kweyodwa.

Ukuphepha kokuthatha iTylenol enezici zegazi

Uma uthatha izinciphisi zegazi, njengeCoumadin, iPlavix, noma i-Eliquis, udokotela wakho angancoma ukuthatha iTylenol ngezinhlungu kune-aspirin noma ibuprofen. Abanye abantu bathatha kokubili i-aspirin nelinye igazi elincanyana, kodwa kuphela ngaphansi kwezincomo zodokotela babo.

Odokotela ngeke bavame ukuncoma ukuthatha iTylenol uma unomlando wezinkinga zesibindi. Lokhu kufaka phakathi i-cirrhosis noma i-hepatitis. Lapho isibindi sesivele sonakele, udokotela angase asikisele ukuthatha isiqabu sobuhlungu esingaphazamisi isibindi.

Ukukhetha isiqabu sobuhlungu

Ama-Tylenol, ama-NSAID, kanye ne-aspirin konke kungaba ukuqeda izinhlungu okusebenzayo. Kodwa-ke, kungahle kube nezimo lapho ukuncipha kobuhlungu okungcono kunenye.

Ngineminyaka engu-17 ubudala, futhi ngidinga isiqabu sobuhlungu. Yini okufanele ngiyithathe?

Gwema ukuthatha i-aspirin, ngoba yandisa ubungozi be-Reye's syndrome kuleyo minyaka engu-18 nangaphansi. I-Tylenol ne-ibuprofen zingasebenza futhi ziphephe lapho zithathwa njengoba ziqondisiwe.

Nginenkinga yomsipha futhi ngidinga ukuqeda izinhlungu. Yini okufanele ngiyithathe?

Uma unokulimala kwemisipha ngaphezu kobuhlungu, ukuthatha i-NSAID (njenge-naproxen noma ibuprofen) kungasiza ekunciphiseni ukuvuvukala okubangela ubuhlungu. ITylenol nayo izosebenza kulesi simo, kepha ngeke ikhulule ukuvuvukala.

Nginomlando wezilonda ezophayo futhi ngidinga ukuqeda izinhlungu. Yini okufanele ngiyithathe?

Uma unomlando wezilonda, isisu, noma ukopha emathunjini, ukuthatha iTylenol kunganciphisa izingozi zakho zokopha okuqhubekayo uma kuqhathaniswa ne-aspirin noma ibuprofen.

Ukuthatha

I-Tylenol ingaba isidambisi sezinhlungu esiphephile nesisebenzayo nokunciphisa imfiva lapho ithathwa njengoba iqondisiwe. Ayinayo imiphumela yokuncipha kwegazi njengoba kwenza i-aspirin.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, okuwukuphela kwesikhathi okufanele ugweme ngaso iTylenol ukuthi uyaliwa yini noma uma unomlando wezinkinga zesibindi.