I-Isoniazid eneRifampicin: indlela yokusebenza kanye nemiphumela emibi
-Delile
I-Isoniazid ene-rifampicin isidakamizwa esisetshenziselwa ukwelashwa nokuvimbela isifo sofuba, futhi singahlotshaniswa nezinye izidakamizwa.
Leli khambi liyatholakala ezikhemisi kodwa lingatholwa kuphela ngokwethula incwadi kadokotela futhi kufanele lisetshenziswe ngokuqapha, ngenxa yokuphikisana nemiphumela engemihle elethwayo.
Isetshenziswa kanjani
Kuzo zonke izinhlobo zesifo sofuba samaphaphu namaphaphu, ngaphandle kwe-meningitis kanye neziguli ezingaphezu kwesisindo esingama-20 kg, kumele bathathe, nsuku zonke, imithamo ekhonjiswe etafuleni elilandelayo:
| Isisindo | Isoniazid | I-Rifampicin | Amaphilisi |
| 21 - 35 Kg | 200 mg | 300 mg | Iphilisi elilodwa lama-200 + 300 |
| 36 - 45 Kg | 300 mg | 450 mg | Iphilisi elilodwa elingu-200 + 300 nelinye elingu-100 + 150 |
| Ngaphezulu kwama-45 Kg | 400 mg | 600 mg | Amaphilisi amabili ka-200 + 300 |
Umthamo kufanele unikezwe ngomthamo owodwa, okungcono ekuseni esiswini esingenalutho, noma amahora amabili ngemuva kokudla. Ukwelashwa kufanele kwenziwe izinyanga eziyisithupha, kepha udokotela angashintsha umthamo.
Indlela yokusebenza
I-Isoniazid ne-rifampicin yizinto ezilwa namagciwane abanga isifo sofuba, esaziwa njenge Isifo sofuba iMycobacterium.
I-Isoniazid yinto evimbela ukuhlukana okusheshayo futhi iholele ekufeni kwe-mycobacteria, edala isifo sofuba, kanti i-rifampicin iyi-antibiotic evimbela ukuphindaphindeka kwamagciwane abucayi futhi yize inesenzo esilwa namagciwane amaningi, isetshenziswa kakhulu ekwelapheni uchoko nesifo sofuba.
Ngubani ongafanele asebenzise
Lo muthi akufanele usetshenziswe kubantu abaphikisana nanoma iyiphi into ekhona kwifomula, abantu abanezinkinga zesibindi noma izinso noma abantu abathatha imishanguzo engadala ushintsho esibindini.
Ngaphezu kwalokho, akunconywa ukuthi kusetshenziswe ezinganeni ezingaphansi kwama-20 kg wesisindo somzimba, abesifazane abakhulelwe noma labo abancelisayo.
Imiphumela emibi engaba khona
Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwalo muthi ukulahleka kwemizwa emaphethelweni njengezinyawo nezandla kanye nezinguquko esibindi, ikakhulukazi kubantu abaneminyaka engaphezu kwengama-35 ubudala.I-Neuropathy, evame ukubuyiselwa emuva, ivame kakhulu kubantu abangondlekile, izidakwa noma abantu asebavele banezinkinga zesibindi nalapho bevezwa yimithamo ephezulu ye-isoniazid.
Ngaphezu kwalokho, ngenxa yokuba khona kwe-rifampicin, ukulahlekelwa isifiso sokudla, isicanucanu, ukuhlanza, isifo sohudo nokuvuvukala kwamathumbu.
Seluleka
Umfutho wegazi ophakeme nokudla