Ukuhlolwa kwe-Lactate Dehydrogenase (LDH) Isoenzymes

-Delile

• Kuyini ukuhlolwa kwe-isoenzymes ye-lactate dehydrogenase (LDH)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-LDH isoenzymes?
• Kwenzekani ngesikhathi sokuhlolwa kwe-LDH isoenzymes?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Izinkomba

Kuyini ukuhlolwa kwe-isoenzymes ye-lactate dehydrogenase (LDH)?

Lokhu kuhlolwa kukala izinga le-isoenzymes ehlukahlukene ye-lactate dehydrogenase (LDH) egazini. I-LDH, eyaziwa nangokuthi i-lactic acid dehydrogenase, uhlobo lwamaprotheni, owaziwa njenge-enzyme. I-LDH ibamba iqhaza elibalulekile ekwenzeni amandla omzimba wakho. Kutholakala cishe kuzo zonke izicubu zomzimba.

Kunezinhlobo ezinhlanu ze-LDH. Zaziwa ngokuthi ama-isoenzymes. Ama-isoenzymes amahlanu atholakala ngamanani ahlukene ezicutshini emzimbeni wonke.

• I-LDH-1: itholakala kumaseli egazi abomvu nenhliziyo
• I-LDH-2: itholakala kumaseli amhlophe egazi. Kutholakala nasemangqamuzaneni egazi abomvu enhliziyo nabomvu, kepha ngamanani amancane kuno-LDH-1.
• I-LDH-3: itholakala kwizicubu zamaphaphu
• I-LDH-4: itholakala kumaseli amhlophe egazi, kumaseli wezinso nama-pancreas, nama-lymph node
• I-LDH-5: itholakala esibindi nasemisipha yamathambo

Lapho izicubu zilimele noma zigula, zikhipha isoenzymes ye-LDH egazini. Uhlobo lwe-LDH isoenzyme ekhishwe kuncike ekutheni yiziphi izicubu ezilimele. Lokhu kuhlolwa kungasiza umhlinzeki wakho ukuthola indawo nesizathu sokulimala kwezicubu zakho.

Amanye amagama: i-LD isoenzyme, i-lactic dehydrogenase isoenzyme

Kusetshenziselwa ini?

Isivivinyo se-LDH isoenzymes sisetshenziselwa ukuthola indawo, uhlobo, nobukhulu bokulimala kwezicubu. Kungasiza ukuxilonga izimo eziningana ezibandakanya:

• Ukuhlaselwa yinhliziyo kwakamuva
• Ukushoda kwegazi
• Isifo sezinso
• Isifo sesibindi, kufaka phakathi i-hepatitis ne-cirrhosis
• I-pulmonary embolism, igazi elisongela impilo emaphashini

Kungani ngidinga ukuhlolwa kwe-LDH isoenzymes?

Ungasidinga lesi sivivinyo uma umhlinzeki wakho wezokunakekelwa kwempilo esola ukuthi unokulimala kwezicubu ngokuya ngezimpawu zakho kanye / noma ezinye izivivinyo. Ukuhlolwa kwe-LDH isoenzymes kuvame ukwenziwa njengokulandela ukuhlolwa kwe-lactate dehydrogenase (LDH). Ukuhlolwa kwe-LDH futhi kukala amazinga e-LDH, kepha ayihlinzeki ngemininingwane yendawo noma uhlobo lokulimala kwezicubu.

Kwenzekani ngesikhathi sokuhlolwa kwe-LDH isoenzymes?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi noma yimaphi amalungiselelo akhethekile ohlolo lwe-LDH isoenzymes.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisile ukuthi amazinga e-isoenzymes eyodwa noma amaningi e-LDH abengejwayelekile, mhlawumbe kusho ukuthi unohlobo oluthile lwesifo sezicubu noma ukulimala. Uhlobo lwesifo noma ukulimala kuzoya ngokuthi i-LDH isoenzymes inamazinga angajwayelekile. Ukuphazamiseka okubangela amazinga angajwayelekile e-LDH kufaka:

• Ukushoda kwegazi
• Isifo sezinso
• Isifo sesibindi
• Ukulimala kwemisipha
• Isifo senhliziyo
• I-Pancreatitis
• I-mononucleosis ethathelwanayo (i-mono)

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Izinkomba

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6. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2019. Ukuhlolwa kwegazi le-LDH isoenzyme: Ukubuka konke [kuvuselelwe i-2019 Jul 3; icashunwe ngo-2019 Jul 3]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/ldh-isoenzyme-blood-test
7. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2019. I-Health Encyclopedia: Lactate Dehydrogenase Isoenzymes [icashunwe ngo-2019 Jul 3]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=lactate_dehydrogenase_isoenzymes
8. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2019. I-Health Encyclopedia: Pulmonary Embolism [icashunwe ngo-2019 Jul 3]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=p01308

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.