I-Mefloquine: iyini, yenzelwa ini nemiphumela engemihle

-Delile

• Yenzelwe ini
• Ngabe i-mefloquine ikhonjisiwe ekwelapheni ukutheleleka kwe-coronavirus?
• Isetshenziswa kanjani
• Isebenza kanjani
• Ngubani ongafanele asebenzise
• Imiphumela emibi engaba khona

IMefloquine ikhambi eliboniswe ekuvikeleni umalaleveva, kubantu abahlose ukuya ezindaweni lapho kunengozi enkulu yokuthola lesi sifo. Ngaphezu kwalokho, ingasetshenziselwa ukwelapha umalaleveva obangelwa ama-ejenti athile, uma uhlanganiswa nomunye umuthi, obizwa nge-artesunate.

I-Mefloquine iyatholakala ezikhemisi, futhi ingathengwa kuphela lapho kwethulwa incwadi kadokotela.

Yenzelwe ini

I-Mefloquine ikhonjisiwe ukuvikela umalaleveva, kubantu abahlose ukuhambela izindawo ezinabantu abaningi, futhi, uma kuhlotshaniswa ne-artesunate, ingasetshenziswa futhi ukwelapha umalaleveva obangelwa yizisebenzi ezithile.

Ngabe i-mefloquine ikhonjisiwe ekwelapheni ukutheleleka kwe-coronavirus?

Ukusetshenziswa kwe-mefloquine ukwelapha ukutheleleka nge-coronavirus entsha akukanconywa ngoba, yize kukhombisile imiphumela ethembisayo ekwelashweni kwe-COVID-19^[1], izifundo ezengeziwe ziyadingeka ukufakazela ukusebenza nokuphepha kwayo.

Ngaphezu kwalokho, eRussia, kusalashwa uhlobo lwemithi olusebenzayo, nge-mefloquine ehlanganiswe neminye imishanguzo, kepha ayinayo imiphumela eqondile.

Ukuzelapha ngokwakho nge-mefloquine kuyalulekwa futhi kuyingozi, futhi kungaba nemiphumela emibi empilweni.

Isetshenziswa kanjani

Lo muthi kufanele uphuzwe ngomlomo, uphelele nangengilazi yamanzi, ngesikhathi sokudla. Umthamo kufanele unqunywe udokotela, ngokuya ngesifo esithile, ukuqina nokuphendula ngakunye komuthi. Ukuze welashwe ezinganeni, udokotela kufanele futhi alungise umthamo esilinganisweni sakho.

Kubantu abadala, lapho i-mefloquine isetshenziselwa ukuvimbela umalaleveva, kunconywa ukuqala ukwelashwa cishe amasonto amabili kuya kwamathathu ngaphambi kohambo. Ngakho-ke, ithebhulethi eli-1 lama-250 mg ngeviki kufanele linikezwe, lihlale ligcina le rejimeni kuze kube amasonto ama-4 ngemuva kokubuya.

Uma kungenakwenzeka ukuqala imishanguzo yokuvimbela kusenesikhathi, i-mefloquine ingaqalwa kusasele isonto ngaphambi kohambo, kepha-ke, kubalulekile ukwazi ukuthi izehlakalo ezimbi kakhulu zivame ukwenzeka kuze kufike umthamo wesithathu, nethuba lokuvela phakathi nohambo . Ngenye indlela, ungasebenzisa i-mefloquine kumthamo wokulayisha we-750 mg kumthamo owodwa bese uqala uhlobo lwemithi ku-250 mg masonto onke.

Funda ukuthi ungazibona kanjani izimpawu zikamalaleveva nokuthi yini okufanele uyenze.

Isebenza kanjani

I-Mefloquine isebenza kumjikelezo wokuphila we-asexual we-parasite, owenzeka ngaphakathi kwamangqamuzana egazi, ngokwakhiwa kwezakhiwo ezineqembu le-heme, okuvimbela ukungasebenzi kwazo ngama-parasite. Izakhiwo ezakhiwe neqembu lamahhala le-heme zinobuthi kumagciwane.

IMefloquine ayinalo umsebenzi olwa nezinhlobo zesibindi samagciwane, noma nezinhlobo zayo zocansi.

Ngubani ongafanele asebenzise

I-Mefloquine iyaphikiswa kubantu abane-hypersensitivity ezingxenyeni zefomula, ezinganeni ezingaphansi kuka-5 kg ​​noma ngaphansi kwezinyanga eziyisithupha, abesifazane abakhulelwe nangesikhathi bencelisa.

Akufanele futhi isetshenziswe kubantu abanezinkinga zezinso nezesibindi, umlando wokwelashwa kwe-halofantrine wakamuva, umlando wezifo zengqondo njengokucindezeleka, i-bipolar affective disorder noma i-neurosis yokukhathazeka okukhulu kanye nesifo sokuwa.

Imiphumela emibi engaba khona

Eminye yemiphumela emibi engahle yenzeke ngenkathi welashwa nge-mefloquine yisiyezi, ikhanda, isicanucanu, ubuhlungu besisu nohudo.

Ngaphezu kwalokho, yize kuyivelakancane kakhulu, ukuqwasha, ukubona izinto ezingekho, ukushintsha kokuxhumana, ukuguquka kwemizwelo, ukuyaluza, ulaka nokusabela okuphambanisayo nakho kungenzeka.