Yini i-microcytosis nezimbangela eziyinhloko

-Delile

• Izimbangela eziyinhloko zeMicrocytosis
• 1. Thalassemia
• 2. I-spherocytosis eyifa
• 3. Izifo
• 4. Ukushoda kwe-iron anemia
• 5. I-Chronic Disease Anemia

I-Microcytosis yigama elingatholakala kumbiko we-hemogram okhombisa ukuthi ama-erythrocyte mancane kunokujwayelekile, futhi ukutholakala kwama-microcytic erythrocytes nakho kungakhonjiswa ku-hemogram. I-Microcytosis ihlolwa kusetshenziswa inkomba ye-VCM noma i-Average Corpuscular Volume, ekhombisa usayizi omaphakathi wamaseli abomvu egazi, ngenani lesethenjwa eliphakathi kuka-80.0 no-100.0 fL, kepha leli nani lingahluka ngokuya kwelabhorethri.

Ukuze i-microcytosis ibaluleke emtholampilo, kunconywa ukuthi imiphumela ye-VCM ihunyushwe kanye namanye ama-indices alinganiswe ukubalwa kwegazi, njenge-Average Corpuscular Hemoglobin (HCM), inani le-hemoglobin, i-Average Corpuscular Hemoglobin Concentration (CHCM) ne-RDW, okuyi inkomba ekhombisa ukuhluka kosayizi phakathi kwamaseli abomvu egazi. Funda kabanzi nge-VCM.

Izimbangela eziyinhloko zeMicrocytosis

Lapho ukubalwa kwegazi kukhombisa ukuthi i-VCM kuphela eshintshiwe futhi inani liseduze nenani lesethenjwa, imvamisa alinikezwa ukubaluleka, ukukwazi ukumela kuphela isimo sesikhashana nokubizwa nge-discrete microcytosis. Kodwa-ke, lapho amanani ephansi kakhulu kubalulekile ukubheka ukuthi ngabe iyiphi enye inkomba ishintshiwe. Uma amanye ama-indices ahlolwe kusibalo segazi ejwayelekile, kunconywa ukuphinda ukubalwa kwegazi.

Imvamisa, i-microcytosis ihlobene nezinguquko zokudla okunempilo noma ihlobene nokwakheka kwe-hemoglobin. Ngakho-ke, izimbangela eziyinhloko ze-microcytosis yilezi:

1. Thalassemia

I-Thalassemia yisifo sofuzo esibonakala ngezinguquko kwinqubo ye-hemoglobin synthesis, lapho kukhona ukuguquka kokukodwa noma ngaphezulu kwamaketanga e-globin, okuholela ekushintsheni okusebenzayo kumaseli abomvu egazi. Ngaphezu kwe-VCM eshintshiwe, kungenzeka ukuthi amanye ama-indices nawo aguquliwe, njenge-HCM, i-CHCM, i-RDW ne-hemoglobin.

Njengoba kunoshintsho enqubeni yokwakheka kwe-hemoglobin, ukuhanjiswa komoya-mpilo ezicutshini nakho kuyashintshwa, ngoba i-hemoglobin ibhekele le nqubo. Ngakho-ke, ezinye izimpawu ze-thalassemia ziyavela, njengokukhathala, ukucasulwa, ukubola kanye nokuguqulwa enkambisweni yokuphefumula. Funda ukubona izimpawu nezimpawu ze-thalassemia.

2. I-spherocytosis eyifa

I-spherocytosis eyifa noma yokuzalwa yisifo esibonakala ngokushintshwa kolwelwesi lwamangqamuzana abomvu egazi, okwenza abe mancane futhi amelane kancane, ngezinga eliphakeme lokubhujiswa kwamaseli abomvu egazi. Ngakho-ke, kulesi sifo, ngaphezu kwezinye izinguquko, amaseli abomvu amancane ne-CMV encishisiwe angaqinisekiswa.

Njengoba igama layo lisho, i-spherocytosis ifa, okungukuthi, idlula isuka kwesinye isizukulwane iye kwesinye futhi umuntu uzalwa nalolu shintsho. Kodwa-ke, ubucayi besifo bungahluka kuye ngomuntu nomuntu, futhi kubalulekile ukuqala ukwelashwa ngemuva nje kokuzalwa ngokuya ngokuqondiswa kwe-hematologist.

3. Izifo

Ukutheleleka okungamahlalakhona nakho kungaholela kumaseli abomvu amancane we-microcytic, ngoba unomphela womenzeli obhekene nokutheleleka emzimbeni kungaholela ekushodeni kokudla okunempilo kanye nezinguquko kumasosha omzimba, kungashintshi izinkomba ze-hematological kuphela kepha neminye imingcele yelabhorethri.

Ukuqinisekisa ukutheleleka, kubalulekile ukuthi udokotela ayale futhi ahlole okunye ukuhlolwa kwelabhorethri, njengokulinganisa kwe-C-Reactive Protein (CRP), ukuhlolwa komchamo kanye nokuhlolwa kwe-microbiological. Isibalo segazi singaphakamisa ukutheleleka, kepha kudingeka ukuhlolwa okwengeziwe ukuqinisekisa ukuxilongwa nokuqala ukwelashwa okufanele.

4. Ukushoda kwe-iron anemia

Ukushoda kwe-iron anemia, okubizwa nangokuthi i-iron defence anemia, ibonakala ngamanani aphansi ensimbi ajikeleza egazini ngenxa yokungadli kahle i-ayoni noma ngenxa yokopha noma ukuya esikhathini okunzima, isibonelo.

Ukwehla kwenani lensimbi kuphazamisa ngqo inani le-hemoglobin, ngoba kubalulekile ekwenzeni i-hemoglobin. Ngakho-ke, lapho i-iron ingekho, kuncipha inani le-hemoglobin, okuholela ekubonakaleni kwezimpawu nezimpawu ezithile, njengobuthakathaka, ukukhathala njalo, ukuzwa ukuquleka, ukulahleka kwezinwele, ukwenza buthakathaka kwezipikili nokungabi nesifiso sokudla, Ngokwesibonelo.

Izimo eziningi zokushoda kwe-iron anemia zenzeka ngenxa yokushoda kokudla okunempilo. Ngakho-ke, isixazululo ukuguqula imikhuba yokudla, ukwenyusa ukusetshenziswa kokudla okunothe ngensimbi, njengesipinashi, ubhontshisi nenyama. Bona ukuthi ukwelashwa kokushoda kwe-iron anemia kufanele kube kanjani.

5. I-Chronic Disease Anemia

I-anemia yesifo esingelapheki uhlobo olujwayelekile lwe-anemia olwenzeka ezigulini ezilaliswe ezibhedlela, ngezinguquko hhayi kuphela kunani le-CMV, kepha nase-HCM, CHCM, RDW kanye ne-hemoglobin. Lolu hlobo lwe-anemia luvame kakhulu kwiziguli ezinezifo ezingalapheki, izifo zokuvuvukala kanye nama-neoplasms.

Njengoba lolu hlobo lwe-anemia luvame ukwenzeka ngesikhathi sokwelashwa, ukuxilongwa nokwelashwa kusungulwa ngokushesha ukuvimbela ezinye izinkinga zesiguli. Funda kabanzi nge-anemia yezifo ezingamahlalakhona.