I-Myoglobin: iyini, isebenza nokuthi isho ukuthini uma iphakeme

-Delile

• Imisebenzi ye-Myoglobin
• Kwenziwa kanjani ukuhlolwa
• Kusho ukuthini i-myoglobin ephezulu

Ukuhlolwa kwe-myoglobin kwenziwa ukubheka inani lale phrotheyini egazini ukuze kutholakale ukulimala kwemisipha nenhliziyo. Le phrotheni ikhona emisipheni yenhliziyo nakweminye imisipha emzimbeni, inikeze umoya-mpilo odingekayo ekunciphiseni kwemisipha.

Ngakho-ke, i-myoglobin ngokuvamile ayitholakali egazini, ikhishwa kuphela lapho kunokulimala kwemisipha ngemuva kokulimala kwezemidlalo, ngokwesibonelo, noma ngesikhathi sokuhlaselwa yinhliziyo, lapho amazinga ale phrotheni aqala ukwanda egazini Ihora elingu-1 kuya kwele-3 ngemuva kwe-infarction, lifinyelela phakathi kwamahora ayisithupha kuya kwangu-7 bese libuyela kokujwayelekile ngemuva kwamahora angama-24.

Ngakho-ke, kubantu abaphilile, ukuhlolwa kwe-myoglobin akulungile, kuba nokuhle kuphela uma kunenkinga nganoma yisiphi isicubu somzimba.

Imisebenzi ye-Myoglobin

I-Myoglobin ikhona emisipheni futhi inesibopho sokubopha umoya-mpilo nokuyigcina kuze kudingeke. Ngakho-ke, ngesikhathi sokuvivinya umzimba, ngokwesibonelo, umoya-mpilo ogcinwe yi-myoglobin ukhishwa ukuze ukhiqize amandla. Kodwa-ke, lapho kukhona noma isiphi isimo esibeka engcupheni imisipha, i-myoglobin namanye amaprotheni angakhishelwa ekusakazweni.

I-Myoglobin ikhona kuyo yonke imisipha yomzimba, kuhlanganise nemisipha yenhliziyo, ngakho-ke iyasetshenziswa futhi njengophawu lokulimala kwenhliziyo. Ngakho-ke, isilinganiso se-myoglobin egazini siyacelwa lapho kukhona ukusola kokulimala kwemisipha okubangelwa:

• Ukuqina kwemisipha;
• Ukushaya ngamandla emisipheni;
• Ukuvuvukala kwemisipha;
• IRhabdomyolysis;
• Ukudlikizela;
• Isifo senhliziyo.

Yize ingasetshenziswa lapho kusolwa ukuhlaselwa yinhliziyo, isivivinyo okwamanje esisetshenziswa kakhulu ukuqinisekisa ukuxilongwa wukuhlolwa kwe-troponin, okulinganisa ubukhona beprotheni ethile ekhona enhliziyweni kuphela futhi engathonyelwa okunye ukulimala kwemisipha. Funda kabanzi mayelana nokuhlolwa kwe-troponin.

Ngaphezu kwalokho, uma ukutholakala kwe-myoglobin egazini kuqinisekisiwe futhi kunamanani aphezulu kakhulu, ukuhlolwa komchamo kungenziwa futhi ukuhlola impilo yezinso, ngoba amazinga aphezulu kakhulu e-myoglobin angadala ukulimala kwezinso, kuphazamise ukusebenza kwawo.

Kwenziwa kanjani ukuhlolwa

Indlela eyinhloko yokwenza ukuhlolwa kwe-myoglobin ukuqoqa isampula segazi, noma kunjalo, ezimweni eziningi, udokotela angacela nesampula yomchamo, njengoba i-myoglobin ihlungwa futhi isuswe izinso.

Kunoma yikuphi ukuhlolwa, akudingekile ukwenza noma yiluphi uhlobo lokulungiselela, njengokuzila.

Kusho ukuthini i-myoglobin ephezulu

Umphumela ojwayelekile wokuhlolwa kwe-myoglobin awuhle noma ungaphansi kuka-0.15 mcg / dL, ngoba ezimweni ezijwayelekile i-myoglobin ayitholakali egazini, kuphela emisipheni.

Kodwa-ke, lapho amanani angaphezulu kuka-0.15 mcg / dL eqinisekiswa, kukhonjiswa esivivinyweni sokuthi i-myoglobin iphezulu, okuvame ukukhombisa inkinga enhliziyweni noma eminye imisipha emzimbeni, ngakho-ke udokotela anga-oda ezinye izivivinyo .njenge-electrocardiogram noma izimpawu zenhliziyo ukuze zifike ekuxilongweni okuthile.

Izinga eliphakeme le-myoglobin lingaba futhi uphawu lwezinye izinkinga ezingahlobene nemisipha, njengokuphuza ngokweqile noma izinkinga zezinso, ngakho-ke umphumela kufanele uhlale uhlolwe nodokotela ngokuya ngomlando womuntu ngamunye.