Ama-monocyte: ayini kanye nenani lesethenjwa

-Delile

• Ama-monocyte aphezulu
• Ama-monocyte aphansi
• Amanani ayizethenjwa

Ama-monocyte ayiqembu lamaseli omzimba womzimba anomsebenzi wokuvikela umzimba emizimbeni yangaphandle, njengamagciwane namagciwane. Zingabalwa ngokuhlolwa kwegazi okuthiwa yi-leukogram noma ukubalwa okuphelele kwegazi, okuletha inani lamaseli wokuzivikela emzimbeni.

Ama-monocyte akhiqizwa emnkantsheni we-bone futhi ajikeleze amahora ambalwa ekusakazeni, bese edlulela kwezinye izicubu, lapho enza inqubo yokuhlukanisa, ethola igama le-macrophage, elinamagama ahlukene ngokusho kwezicubu atholakala kulo: Amaseli we-Kupffer, esibindi, i-microglia, ohlelweni lwezinzwa, kanye namaseli eLangerhans ku-epidermis.

Ama-monocyte aphezulu

Ukwanda kwenani lama-monocyte, okubizwa nangokuthi i-monocytosis, kuvame ukukhombisa ukutheleleka okungamahlalakhona, njengesifo sofuba, isibonelo. Ngaphezu kwalokho, kungahle kube nokwanda kwenani lama-monocyte ngenxa yesifo sezilonda emathunjini, ukutheleleka kweprotozoal, isifo sikaHodgkin, i-myelomonocytic leukemia, izifo eziningi ze-myeloma kanye nezifo ezizimele njenge-lupus ne-rheumatoid arthritis.

Ukwanda kwama-monocyte akuvamisile ukudala izimpawu, kuqashelwa kuphela ngokuhlolwa kwegazi, inani eliphelele legazi. Kodwa-ke, kungahle kube nezimpawu ezihlobene nembangela ye-monocytosis, futhi kufanele ziphenywe futhi ziphathwe ngokwencomo kadokotela. Qonda ukuthi isibalo segazi siyini nokuthi senzelani.

Ama-monocyte aphansi

Lapho amanani we-monocyte ephansi, isimo esibizwa nge-monocytopenia, kuvame ukuthi kusho ukuthi amasosha omzimba ayantengantenga, njengasesimweni sokutheleleka ngegazi, ukwelashwa ngamakhemikhali kanye nezinkinga zomnkantsha, njenge-aplastic anemia kanye neleukemia. Ngaphezu kwalokho, amacala okutheleleka kwesikhumba, ukusetshenziswa kwama-corticosteroids kanye ne-HPV kungadala nokwehla kwenani lama-monocyte.

Ukubukeka kwamanani asondele ku-0 wama-monocyte egazini akuvamile futhi, lapho kwenzeka, kungasho ukuba khona kwe-MonoMAC Syndrome, okuyisifo sofuzo esibonakala ngokungabikho kwama-monocyte ngomnkantsha, kungaholela ekutheleleni, ikakhulukazi esikhunjeni. Kulezi zimo, ukwelashwa kwenziwa ngemithi yokulwa nokutheleleka, njengama-antibiotic, futhi kungadingeka ukuthi kwenziwe ukufakelwa umnkantsha ukuze kulashwe inkinga yofuzo.

Amanani ayizethenjwa

Amanani esithenjwa angahluka ngokuya kwelabhorethri, kepha imvamisa ilingana no-2 kuya ku-10% wamasokocyte aphelele noma phakathi kwama-monocyte angama-300 kuya kwangu-900 nge-mm³ yegazi.

Ngokuvamile, izinguquko enanini lala maseli azizibangeli izimpawu esigulini, esizizwa kuphela izimpawu zesifo esibangela ukwanda noma ukwehla kwama-monocyte. Ngaphezu kwalokho, kwezinye izimo isiguli sithola kuphela ukuthi kunoshintsho oluthile lapho kwenziwa ukuhlolwa kwegazi okujwayelekile.