Okufanele Ukwenze Uma Ukwelashwa Kwakho Kwe-HCC Kwamanje Kungasebenzi

-Delile

• Sibutsetelo sokwelashwa
• Izindlela zokwelashwa ezihlosiwe
• Izilingo zezidakamizwa
• Izindlela zokwelapha ezi-palliative kanye nezinye

Akuwona wonke umuntu ophendula ekwelashweni kwe-hepatocellular carcinoma (HCC) ngendlela efanayo. Uma ukwelashwa kwakho kungakwenzi lokho okufanele ukwenze, uzofuna ukuba nombono wokuthi yini ezolandela ngokulandelayo.

Thola ulwazi ngezindlela zokwelashwa zakamuva, izivivinyo zezidakamizwa, nokuthi yini ongayibuza udokotela wakho lapha.

Sibutsetelo sokwelashwa

Udokotela wakho uzokwakha uhlelo lwakho lokuqala lokwelashwa ngokuya ngezici ezinjenge:

• isigaba somdlavuza lapho uxilongwa
• ngabe umdlavuza usukhule waba yimithambo yegazi noma cha
• iminyaka yakho nempilo ejwayelekile
• uma ukuvuselelwa kokuhlinzwa noma ukufakelwa kwesibindi kungenzeka
• sisebenza kahle kanjani isibindi sakho

Esikhathini sokuqala somdlavuza wesibindi, ukuhlinzwa ukuze ususe isimila nengxenye encane yesibindi sakho kungaba yikho konke okudingayo. Uma umdlavuza ungakagcini, ungahle ufaneleke ukufakelwa isibindi. Uma ukuhlinzekwa kungeyona inketho, amasu ahlukahlukene okukhipha isisu angabhubhisa izicubu ezincane esibindini ngaphandle kokuzisusa.

Ungadinga futhi ezinye izindlela zokwelashwa eziqhubekayo ezifana nemisebe noma i-chemotherapy. Noma ngabe yiziphi izindlela zokwelashwa ogcina uzikhethile, iqembu lakho lokunakekelwa kwezempilo lizolandela ukuze libone ukuthi lisebenza kahle kangakanani. Udokotela wakho angalungisa uhlelo lwakho lwezokwelapha njengoba kudingeka.

Okulandelayo ngezinye izinto ezimbalwa okufanele uzikhumbule lapho ukwelashwa kungasebenzi.

Izindlela zokwelashwa ezihlosiwe

I-HCC ingelashwa ngemithi ekhomba izinguquko ezithile kumaseli adala umdlavuza. Kanye egazini lakho, le mithi ingafuna amangqamuzana omdlavuza noma yikuphi emzimbeni wakho. Yingakho zingasetshenziselwa umdlavuza osakazeke ngaphandle kwesibindi.

Ngomdlavuza wesibindi, i-sorafenib (Nexavar) ingaba isidakamizwa sokuqala udokotela wakho azozama. Amaseli womdlavuza aqukethe amaprotheni awakhuthazayo ukuba akhule, futhi lo muthi ukhomba lawo maprotheni. Izicubu nazo zidinga ukwakha imithambo yegazi emisha ukuze ikhule, futhi i-sorafenib ivimba lesi senzo. Ngokuvamile kunemiphumela emibi embalwa kunaleyo obuyoba nayo ngekhemotherapy. Ngoba itholakala kwifomu lephilisi, futhi kulula ukuthatha.

Uma i-sorafenib ingasebenzi, udokotela wakho angancoma i-regorafenib (Stivarga). Isebenza ngokufanayo, kepha igcinelwe labo asebephathwe nge-sorafenib.

Ukwelashwa okusha okubhekiswe komdlavuza wesibindi osezingeni eliphakeme yi-nivolumab (Opdivo), enikezwa ngomjovo. INivolumab inikezwe imvume esheshayo kubantu abane-HCC abaphathwe nge-sorafenib. Izifundo zokuqala kubantu abanomdlavuza wesibindi esithuthukile zikhombisa imiphumela ekhuthazayo.

Uma udokotela wakho encoma ukwelashwa nge-sorafenib, buza:

• Yikuphi ukuhlolwa kokulandelela okuzosetshenziselwa ukuthola ukuthi kuyasebenza yini?
• Kukusiphi isikhathi lapho sizokwazi khona ngokuqinisekile ukuthi sekuyisikhathi sokwenza ushintsho?

Uma i-sorafenib ingasebenzi, noma njengoba iyekile ukusebenza:

• Ingabe isinyathelo esilandelayo regorafenib noma i-nivolumab?
• Iyiphi inketho engcono kimi futhi ngani?
• Sizokwazi kanjani ukuthi iyasebenza?
• Uma kungasebenzi, yiziphi izinyathelo ezilandelayo?

Izilingo zezidakamizwa

Inqubo esukela ocwaningweni yokuthola umuthi ovunyelwe ukwelashwa yinde. Ukuhlolwa kwemitholampilo kuphakathi kwezinyathelo zokugcina kuleyo nqubo. Lezi zivivinyo zincike kubantu abavolontiya ekwelashweni kokuhlola. Kuwe, kusho ukufinyelela kuzindlela zokwelapha ezintsha ezingakavunyelwa ukusetshenziswa ngokujwayelekile.

Izilingo eziqhubekayo zokwelashwa kwe-HCC zifaka izindlela zokwelapha ezahlukahlukene ezisebenzisa amasosha omzimba ukulwa nomdlavuza. Le mithi ifaka ama-immune checkpoint inhibitors, ama-antibody monoclonal, ukwelashwa kwamaseli okutholwa, kanye nokwelashwa kwamagciwane e-oncolytic.

Ukuthola eminye imininingwane ngokuhlolwa komdlavuza wesibindi, vakashela i-American Cancer Society's Clinical Trial Matching Service noma iCancer Research Institute's Clinical Trial Finder.

Udokotela wakho angakusiza ukukuqondisa endaweni efanele. Nayi imibuzo embalwa ongayibuza:

• Ngikufanele yini ukuhlolwa kwasemtholampilo?
• Uyini umgomo wecala?
• Kube yini okuhlangenwe nakho kokwelapha okusha kuze kube manje?
• Izokwenziwa kanjani futhi yini ezocelwa kimi?
• Yiziphi izingozi ezingaba khona?

Izindlela zokwelapha ezi-palliative kanye nezinye

Ngenkathi iqembu lakho le-oncology liphatha umdlavuza, ungathola nokwelashwa kokuphathwa kwezimpawu. Ukunakekelwa okusekelayo kwaziwa nangokuthi ukunakekelwa okunciphisayo.

Ochwepheshe bokunakekelwa kwe-Palliative abawelaphi umdlavuza uqobo ngalunye. Baqeqeshelwe ukugxila ebuhlungwini nakwezinye izimpawu zomdlavuza nokwelashwa kwawo. Inhloso yabo ukwenza ngcono impilo yakho. Bazoxhumana nabanye odokotela bakho ukuze baqiniseke ukuthi izindlela zakho zokwelapha zisebenza kahle ngokubambisana nokugwema ukuhlangana kwezidakamizwa okubi.

Ungabheka futhi ekwelashweni okuhambisanayo nokunye. Lokhu kungafaka ukwelashwa ngokutholwa, ukubhucungwa, nezindlela zokuphumula. Qiniseka ukuthi uthintana nodokotela wakho ukuze uqiniseke ukuthi izindlela zokwelashwa ezintsha ziphephile kuwe nokuthi usebenzisa ochwepheshe abaqeqeshiwe.

Ngaphambi kokuthatha izithako ezintsha zemithi noma yokudla, buza odokotela bakho ukuthi bazophazamisa yini eminye imithi.

Ukwelapha umdlavuza wesibindi kuvame ukufaka iqembu elandisiwe. Odokotela nabanye ochwepheshe bezokunakekelwa kwezempilo badinga ukusebenzisana ukuze banikeze ukunakekelwa komuntu siqu.