Kusetshenziswe

-Delile

• Izinkomba ze-Probenecida
• Ungayisebenzisa kanjani i-Probenecada
• Imiphumela emibi ye-Probenecida
• Ukuphikisana kweProbenecida

I-Probenecid ikhambi lokuvikela ukuhlaselwa yi-gout, ngoba kusiza ukuqeda i-uric acid eyeqile emchameni.

Ngaphezu kwalokho, i-probenecid nayo isetshenziswa ngokuhlangana namanye ama-antibiotic, ikakhulukazi ekilasini le-penicillin, ukwandisa isikhathi sakho emzimbeni.

Izinkomba ze-Probenecida

I-Probenecida ikhonjisiwe ekuvimbeleni izingqinamba ze-gout, njengoba kusiza ukujwayelekile amazinga e-uric acid egazini. Ngaphezu kwalokho, kukhonjiswa ukuthi kukhulisa isikhathi semithi elwa namagciwane, ikakhulukazi isigaba sepenicillin, emzimbeni.

Ungayisebenzisa kanjani i-Probenecada

Ungayisebenzisa kanjani i-Probenecida kufaka phakathi:

• Beka: ithebhulethi eyodwa engama-250 mg kabili ngosuku isonto elilodwa. Ngemuva kwalokho, shintshela kumathebulethi angu-500 mg kabili ngosuku isikhathi esiyizinsuku ezi-3;
• Ihambisana namanye ama-antibiotic:
  • Abantu abadala nezingane ezingaphezu kweminyaka engu-14 noma abanesisindo esingaphezu kwama-50 kg: ithebhulethi engu-500 mg izikhathi ezine ngosuku;
  • Izingane ezineminyaka engu-2 kuya kwengu-14 noma ezinesisindo esingaphansi kwama-50 kg: qala ngo-25 mg ngekhilogremu ngayinye, ngemithamo ehlukanisiwe, njalo emahoreni ayisithupha. Bese udlulela ku-40 mg ngekhilogremu yesisindo, ngemithamo ehlukanisiwe, njalo emahoreni ayisithupha.

Imiphumela emibi ye-Probenecida

Imiphumela emibi ye-Probenecida ifaka ukungabi nesifiso sokudla, isicanucanu, ukuhlanza, i-erythema, ukulunywa okujwayelekile, ukuqubuka kwesikhumba kanye ne-renal colic.

Ukuphikisana kweProbenecida

I-Probenecida iyaphikiswa ekunceliseni ibele, ezigulini ezinamatshe ezinso, ezinganeni ezineminyaka engaphansi kwemibili ubudala, ukuphatha inkinga ebucayi ye-gout, ezigulini ezinokungezwani komzimba ne-probenecid noma ezigulini ezinoshintsho kumaseli egazi.

Ukusetshenziswa kwe-Probenecida kwabesifazane abakhulelwe, ezigulini ezinokukhubazeka kwezinso, ezigulini ezine-peptic ulcer noma i-porphyria kufanele kwenziwe kuphela ngaphansi kokuqondiswa nokwelashwa.