Okufanele Ukwazi Ngokushoda Kwamaprotheni C

-Delile

• Ziyini izimpawu zokushoda kwamaprotheni C?
• Yini ebangela ukuntuleka kwamaprotheni C?
• Kutholakala kanjani?
• Ukushoda kwamaprotheni C nokukhulelwa
• Ungakulapha kanjani ukushoda kwamaprotheni C?
• Uyini umbono?
• Amathiphu okuvimbela

Kuyini ukushoda kwamaprotheni C?

Amaprotheni C yiprotheni ekhiqizwa isibindi. Kutholakala ekugxileni okuphansi ekusakazweni kwegazi. Akusebenzi kuze kusebenze uvithamini K.

Amaprotheni C enza imisebenzi ehlukahlukene. Umsebenzi wawo omkhulu ukuvimbela igazi ekunqandeni. Uma untula amaprotheni C, igazi lakho kungenzeka likwazi ukujiya kunomuntu onamazinga ajwayelekile. Izinga eliphakeme kunelejwayelekile lamaprotheni C alihlotshaniswa nanoma yiziphi izingqinamba zezempilo ezaziwayo. Kepha kungakhuphula ukopha.

Ukushoda kwamaphrotheni C kutholakala kumazinga afanayo kwabesilisa nabesifazane, naphakathi kwezinhlanga ezahlukahlukene.

Ziyini izimpawu zokushoda kwamaprotheni C?

Kwezinye izimo, umuntu onamaphutha we-protein C kungenzeka angakhombisi izingqinamba zokuvala noma ezinye izimpawu. Ngezinye izikhathi, ukuntuleka kweprotheni C kungaholela emazingeni aphezulu wokujiya kwegazi.

Ukujiya kwegazi kungaxhunyaniswa nezimo ezahlukahlukene:

• I-vein thrombosis ejulile (i-DVT): Amahlule emithanjeni yemilenze angadala ubuhlungu, ukuvuvukala, ukushintsha kombala kanye nokuthamba. Ubukhali ngokuvamile buxhomeke kubukhulu behlwili. Uma i-DVT ingekho emlenzeni, ungahle ungabi nazimpawu ezibonakalayo.
• I-pulmonary embolism (PE): I-PE ingaholela ezinhlungwini zesifuba, umkhuhlane, isiyezi, ukukhwehlela nokuphefumula okuncane.
• I-Neuratal purpura: Lesi simo siyabonakala ezinganeni ezisanda kuzalwa. Izimpawu zivela kungakapheli amahora ayi-12 ngemuva kokuzalwa futhi zifaka phakathi izilonda zesikhumba eziqala zibe bomvu bumnyama bese iba nsomi ngokubomvu.
• I-thrombophlebitis: Lesi simo sidala ukuvuvukala nokubomvu engxenyeni ethintekile yomthambo.

Ngayinye yalezi zimo inezimpawu zayo ezihlukile.

Abantu abanokushoda kwamaprotheni C banengozi eyengeziwe ye-DVT ne-PE.

Yini ebangela ukuntuleka kwamaprotheni C?

Ukushoda kwamaphrotheni C kungazuzwa njengefa, kutholakale, noma kuthuthuke ngokuhamba kwesikhathi njengomphumela wezinye izimo.

Ukushoda kwamaprotheni C kubangelwa ufuzo, noma ukuzuzwa njengefa. Lokho kusho ukuthi kungenzeka ukuthi uyithuthukise uma unomlando womndeni wokuntuleka kwamaprotheni C. Unethuba elingamaphesenti angama-50 lokulithuthukisa uma omunye wabazali bakho enesifo samaprotheni C. Cishe umuntu oyedwa kwabangama-500, noma amaphesenti ayi-0.2 eningi labantu anephutha le-protein C.

Futhi ungakhulisa ukushoda kweprotheni C ngaphandle kwesixhumanisi sezakhi zofuzo. Izimo ezingaholela ekushodeni kweprotheni C zifaka:

• ukuntuleka kukavithamini K
• ukusetshenziswa kwe-thinner yegazi efana ne-warfarin (Coumadin, Jantoven)
• ukwehluleka kwesibindi
• izimila zemetastatic ezisabalele
• ukugula okunzima, kubandakanya ukutheleleka
• kusatshalaliswa i-coagulation ye-intravascular

Ukwehla okutholakele kwamazinga wamaprotheni C akubalulekile emtholampilo ngendlela okuzuze ngayo ukuntuleka kweprotheni C.

Kutholakala kanjani?

Ukuhlolelwa amaprotheni C kuyashesha futhi kulula. Udokotela wakho uzothatha ukudonsa okulula kwegazi bese enza isivivinyo ukuthola izinga leprotheyini C egazini lakho. Udokotela kufanele enze ukuhlolwa emasontweni ambalwa ngemuva kwesiqephu se-clot yegazi, futhi ngemuva kokuyeka ukuthatha imithi ethile yokunciphisa igazi, njenge-warfarin (i-Coumadin, i-Jantoven).

Udokotela wakho angenza ukuhlolwa kwegazi ngoba kuvame ukwenziwa ngamanga.

Ukushoda kwamaprotheni C nokukhulelwa

Abesifazane abanokushoda kwamaprotheni C basengozini enkulu yokuba namahlule phakathi nangemva kokukhulelwa. Lokho kungenxa yokuthi ukukhulelwa kuyingcuphe yokuthuthukisa amahlule egazi.

Abaphenyi bakholelwa ukuthi ukuntuleka kwamaprotheni C kungakhuphula ubungozi bokukhulelwa yizisu ekuqaleni nangesikhathi sokukhulelwa. Khuluma nodokotela wakho uma ucabanga ukuthi usengozini yokushoda kwamaprotheni C. Ngokubambisana ningeza nohlelo lokukhulelwa okuphephile nokubeletha.

Ungakulapha kanjani ukushoda kwamaprotheni C?

Imithi ezinciphisa igazi, eyaziwa nangokuthi ama-anticoagulants, ingaphatha ukuntuleka kwamaprotheni C. Le mithi inciphisa ingozi yokwakheka kwegazi ngokuvimbela igazi ekunqandeni emithanjeni yegazi. Imithi ngeke ivumele amahlule ukuba akhule, futhi ngeke ihlukanise amahlule asevele akha.

Ama-thinner egazi afaka i-heparin (Hep-Lock U / P, Monoject Prefill Advanced Heparin Lock Flush), ejojowe, ne-warfarin (i-Coumadin, i-Jantoven), i-anticoagulants yomlomo eqondile ethathwe ngomlomo. Uhlelo lokwelashwa lungahlanganisa ukujova i-heparin esikhunjeni sakho isonto lokuqala, bese uthatha umuthi womlomo ngemuva kwesonto lokuqala.

Uyini umbono?

Ukushoda kwamaphrotheni C akuvamile. Uma ushoda, umbono wakho muhle. Abantu abaningi abanamaprotheni C abanayo imiphumela emibi ebonakalayo. Uma ukujiya kuyinkinga, kunezindlela eziningi zokuphatha nokukuvimbela ngokwenza okulandelayo:

• ukuthatha imithi efanele
• ukugcina impilo enempilo
• ukwenza okuthile ngesimo sakho

Amathiphu okuvimbela

Ungahle ungakwazi ukuvimbela ukuntuleka kweprotheni C, kepha ungathatha izinyathelo zokunciphisa ubungozi bamahlule egazi:

• Vocavoca umzimba njalo.
• Thatha yonke imithi enikezwe udokotela wakho.
• Gqoka amasokisi abizwa nge- “compression stockings” uma udokotela wakho ekuyala.
• Gwema ukuma noma ukuhlala isikhathi eside.
• Hlala u-hydrated. Phuza amanzi amaningi usuku lonke.

Futhi, uma unomlando womndeni wokuntuleka kwamaprotheni C noma ukuvala igazi, khuluma nodokotela wakho ngohlelo lokuvimbela. Ukusebenza kuqala kuyisinyathelo sakho esihle sokuvimbela.